Researchers from the University of Kentucky and the University of Missouri - Columbia have teamed up on a pioneering cardiovascular study titled “Dual Filament Control of Myocardial Power and Hemodynamics.” The UK team is led by cardiovascular medicine’s Thomas Kampourakis, Diplom, PhD, and Kenneth Campbell, PhD, associate vice chair of translational science. Alongside the University of Missouri team, they have been awarded a multi–Principal Investigator (multi-PI) R01 grant from the National Heart, Lung, and Blood Institute (NHLBI).

The funding will support innovative research to "identify high-value therapeutic targets to optimize ventricular performance in heart failure patients." The project emphasizes interprofessional collaborations between scientists, clinicians, and computational modeling to advance understanding of the mechanisms that regulate myocardial contractility.

The project not only reinforces the University of Kentucky’s commitment to impactful, translational science but also underscores the role of inter-institutional partnerships in addressing some of the most urgent challenges in cardiovascular medicine.

Research reported in this publication was supported by the National Heart, Lung, and Blood Institute of the National Institutes of Health under Award Numbers R01HL149164 and R01HL148785. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.