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About the UK Sanders-Brown Center on Aging

The Sanders-Brown Center on Aging at the University of Kentucky is a nationally-recognized leader in brain aging research and clinical care. As home to one of the world's premier brain banks, we investigate the causes of Alzheimer’s disease and related dementias, advance early detection tools and personalized treatments, and train future scientists.

Research & Training Highlights

With more than four decades of NIH support, Sanders-Brown drives groundbreaking studies in neuroinflammation, TDP-43 pathology, LATE, and vascular contributions to cognitive impairment (VCID). 

Our center offers unique opportunities for research collaboration, clinical training, and data sharing through longitudinal cohort studies, autopsy programs, and translational trial initiatives.

Featured Research Programs

• Alzheimer’s Disease Research Center (ADRC) 

• Brain Aging and Neurodegeneration Studies 

• TRIAD T32 Training Program 

• Clinical Trials in Alzheimer’s and Dementia

Explore Our Research

Drug studied at UK is first disease-modifying therapy in U.S. approved to treat Alzheimer’s

In 2023, the FDA fully approved Leqembi (lecanemab) for Alzheimer’s treatment. UK’s Sanders-Brown Center on Aging has studied this and similar drugs for over a decade.

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Verda Davis

40 Years of NIH Alzheimer's Disease Research Center Designation

Sanders-Brown Center on Aging celebrates 40 years as one of the original 10 NIH Alzheimer’s Disease Research Centers. Our history of discovery and clinical leadership continues to shape the future of cognitive aging science in Kentucky and beyond.