A picture of a white brain, with the hands of a clock overlapping it. The background is evenly split between stars at night and clouds in the day.

Scientists have long recognized the brain’s need for energy, but groundbreaking research from the University of Kentucky’s Sanders-Brown Center on Aging has now illuminated how the brain’s energy utilization significantly influences our sleep patterns. 

Ryan Shahidehpour

My name is Ryan Shahidehpour, and as a postdoctoral researcher in lab of Pete Nelson, MD, PhD, in the Sanders-Brown Center on Aging, I investigate pathological changes that drive neurodegenerative diseases associated with aging in the human brain.

silly socks

Down syndrome is the most commonly diagnosed chromosomal condition in the United States. Each year, approximately 6,000 babies are born with Down syndrome, meaning it affects about one in every 700 births. This genetic condition results from the presence of an extra copy of chromosome 21, known as trisomy 21, which impacts physical and cognitive development to varying degrees.

Linda Van Eldik sitting in a computer lab, leaning against a table.

The University of Kentucky Alzheimer’s Disease Research Center at the Sanders-Brown Center on Aging is celebrating 40 years of groundbreaking research in the fight against dementia.

Elika Moallem

My name is Elika Moallem, and I am a third-year graduate student in the department of neuroscience, working under the mentorship of Adam Bachstetter, PhD. My research focuses on the interrelationship between traumatic brain injury (TBI) and Alzheimer’s disease (AD), particularly how metabolic dysfunction after TBI contributes to neurodegeneration.

Behind the blue logo, a microphone seeming to wear a set of headphones, beside the text "behind the blue" University of Kentucky

The University of Kentucky Alzheimer’s Disease Research Center at the Sanders-Brown Center on Aging is celebrating 40 years of research and community impact. The center is world-renowned for its significant contributions to the field through the decades.

Kentucky Edition
Shannon, Kristen, and Lance

The University of Kentucky College of Medicine continues to solidify its reputation as a hub for groundbreaking biomedical research. In December, the UK CNS-Met (central nervous system-metabolism) Center of Biomedical Research Excellence (COBRE), a program funded by the National Institutes of Health (NIH), hosted its inaugural research symposium. 

Pete Nelson and Greg Jicha

Researchers at the University of Kentucky’s Sanders-Brown Center on Aging are at the forefront of advancing dementia research with groundbreaking work on a condition known as LATE, or “limbic predominant age-related TDP-43 encephalopathy.” 

Greg Jicha, MD, PhD, director of clinical trials at UK’s Sanders-Brown Center on Aging, conducts an exam.

Researchers at the University of Kentucky (UK) are part of a groundbreaking clinical trial exploring the use of medical marijuana in managing symptoms of late-stage dementia.

Dr. Greg Jicha and Dr. Pinar Coskun conduct an exam on February 15, 2024.

As Kentucky prepares for its launch of legalized medical marijuana, work is already underway inside the University of Kentucky’s Sander-Brown Center on Aging, where doctors and researchers are working to gauge the benefit of marijuana on advanced stages of dementia with agitation. Six months into their clinical trial, they’re seeing promising data.

Photo of people walking

The University of Kentucky Public Relations & Strategic Communications Office provides a weekly health column available for use and reprint by news media.

Several healthy foods layered together in the shape of the human brain.

Researchers at the University of Kentucky have found that incorporating specific nutrients into a regular diet may reduce iron buildup in the brain — a factor associated with cognitive decline in normal aging.

A doctor referencing a patient's brain scans.

With age comes disease. Cancer and Alzheimer’s dementia are among the commonest and most feared health conditions – particularly in countries with ageing populations such as the UK.

Photo of Caregiver

This article appeared in the Lane Report.

While some Americans in their 60s and older may have a vague memory of doctors making house calls with their black medical bag, home healthcare in the 2020s is starkly different than that slice of Americana from the 1950s.

Atcharaporn Ontawong

My name is Atcharaporn Ontawong, and I am a second-year postdoctoral scholar at the Sanders-Brown Center on Aging under the mentorship of Anika Hartz, PhD.  My journey with the Hartz lab began in 2018 when, as a PhD student from Thailand, I joined the group through a scholarship from Thailand's Research and Researcher for Industry program.

Elaf Ghoneim working in a UK laboratory under a hood ventilator.

Recent University of Kentucky graduate Elaf Ghoneim was born and raised in Lexington, Kentucky. Her family, originally from Libya, established a tight-knit, community-oriented home that emphasized the importance of service and advocacy.

Linda J. Van Eldik working in her laboratory

The University of Kentucky Sanders-Brown Center on Aging Director Linda Van Eldik, PhD, hopes to shed light on how specific brain cells may contribute to the progression of Alzheimer’s disease, paving the way for potential new therapeutic approaches.

Bob Sompol, Yang Jiang, & Chris Norris

Reyna Katko

LOUISVILLE, Ky. (WDRB) -- University of Kentucky researchers made a major breakthrough in understanding long COVID: it could lead to Alzheimer’s-like brain changes.

"I was shocked how people will find COVID in their brain," Dr. Yang Jiang said.

Blaine Weiss

My name is Blaine Weiss, and I am a graduate student in the department of pharmacology and nutritional sciences in the lab of Christopher Norris, PhD. Our group studies the role of astrocyte reactivity in contributing to the progression of Alzheimer’s disease.