News

Scientists have long recognized the brain’s need for energy, but groundbreaking research from the University of Kentucky’s Sanders-Brown Center on Aging has now illuminated how the brain’s energy utilization significantly influences our sleep patterns.

My name is Ryan Shahidehpour, and as a postdoctoral researcher in lab of Pete Nelson, MD, PhD, in the Sanders-Brown Center on Aging, I investigate pathological changes that drive neurodegenerative diseases associated with aging in the human brain.

Down syndrome is the most commonly diagnosed chromosomal condition in the United States. Each year, approximately 6,000 babies are born with Down syndrome, meaning it affects about one in every 700 births. This genetic condition results from the presence of an extra copy of chromosome 21, known as trisomy 21, which impacts physical and cognitive development to varying degrees.
The University of Kentucky Alzheimer’s Disease Research Center at the Sanders-Brown Center on Aging is celebrating 40 years of groundbreaking research in the fight against dementia.

My name is Elika Moallem, and I am a third-year graduate student in the department of neuroscience, working under the mentorship of Adam Bachstetter, PhD. My research focuses on the interrelationship between traumatic brain injury (TBI) and Alzheimer’s disease (AD), particularly how metabolic dysfunction after TBI contributes to neurodegeneration.

The University of Kentucky Alzheimer’s Disease Research Center at the Sanders-Brown Center on Aging is celebrating 40 years of research and community impact. The center is world-renowned for its significant contributions to the field through the decades.

January 23, 2025

The University of Kentucky College of Medicine continues to solidify its reputation as a hub for groundbreaking biomedical research. In December, the UK CNS-Met (central nervous system-metabolism) Center of Biomedical Research Excellence (COBRE), a program funded by the National Institutes of Health (NIH), hosted its inaugural research symposium.

Researchers at the University of Kentucky’s Sanders-Brown Center on Aging are at the forefront of advancing dementia research with groundbreaking work on a condition known as LATE, or “limbic predominant age-related TDP-43 encephalopathy.”

Researchers at the University of Kentucky (UK) are part of a groundbreaking clinical trial exploring the use of medical marijuana in managing symptoms of late-stage dementia.

As Kentucky prepares for its launch of legalized medical marijuana, work is already underway inside the University of Kentucky’s Sander-Brown Center on Aging, where doctors and researchers are working to gauge the benefit of marijuana on advanced stages of dementia with agitation. Six months into their clinical trial, they’re seeing promising data.

The University of Kentucky Public Relations & Strategic Communications Office provides a weekly health column available for use and reprint by news media.

Researchers at the University of Kentucky have found that incorporating specific nutrients into a regular diet may reduce iron buildup in the brain — a factor associated with cognitive decline in normal aging.

With age comes disease. Cancer and Alzheimer’s dementia are among the commonest and most feared health conditions – particularly in countries with ageing populations such as the UK.

This article appeared in the Lane Report.
While some Americans in their 60s and older may have a vague memory of doctors making house calls with their black medical bag, home healthcare in the 2020s is starkly different than that slice of Americana from the 1950s.

My name is Atcharaporn Ontawong, and I am a second-year postdoctoral scholar at the Sanders-Brown Center on Aging under the mentorship of Anika Hartz, PhD. My journey with the Hartz lab began in 2018 when, as a PhD student from Thailand, I joined the group through a scholarship from Thailand's Research and Researcher for Industry program.

Recent University of Kentucky graduate Elaf Ghoneim was born and raised in Lexington, Kentucky. Her family, originally from Libya, established a tight-knit, community-oriented home that emphasized the importance of service and advocacy.
The University of Kentucky Sanders-Brown Center on Aging Director Linda Van Eldik, PhD, hopes to shed light on how specific brain cells may contribute to the progression of Alzheimer’s disease, paving the way for potential new therapeutic approaches.

Reyna Katko
LOUISVILLE, Ky. (WDRB) -- University of Kentucky researchers made a major breakthrough in understanding long COVID: it could lead to Alzheimer’s-like brain changes.
"I was shocked how people will find COVID in their brain," Dr. Yang Jiang said.

My name is Blaine Weiss, and I am a graduate student in the department of pharmacology and nutritional sciences in the lab of Christopher Norris, PhD. Our group studies the role of astrocyte reactivity in contributing to the progression of Alzheimer’s disease.