A PAINFUL ADDICTION

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The bodies of mammals, including humans, respond to injury by releasing endogenous opioids — compounds that mitigate acute pain. A team of researchers, led by those at the University of Kentucky, has uncovered groundbreaking new information about how the body responds to traumatic injury with the development of a surprisingly long-lasting opioid mechanism of natural chronic pain control. Remarkably, the body develops both physical and physiological dependence on this opioid system, just as it does on opiate narcotic drugs.
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Welcome to the UK Physiology website. You’ll find that our department is a large, diverse community. We have 32 primary faculty, 50 trainees, and almost a hundred laboratory and administrative staff. Our scientific expertise ranges from neurophysiology to cardiovascular biology, from reproductive endocrinology to muscle biology. With $6.8M in extramural support this year, our award-winning investigators are making major advances in biomedical research. Our training programs are preparing scientists for successful careers in academia, industry, and government.