Grants in Progress (GiPs)

2017 Grants in Progress

  • Brian Delisle, PhD

    "A gene-first approach for the early diagnosis of long QT syndrome type 2"
    Wednesday, Feb 15, 2017

  • Drs. Gregory Frolenkov and Kathy Saatman 

    "Stereocilia Actin Core Repair in Noise-Induced Hearing Loss"
    Wednesday, March 22, 2017

  • Melinda Wilson, PhD

    "Managing neonatal abstinence syndrome"
    Wednesday, April 26, 2017

  • Lance Johnson, PhD

    "APOE and the Pentose Phosphate Pathway:  Linking Glucose Metabolism and Cell Survival in Age-Related Disorders​​​​​​​"
    Wednesday, May 10, 2017

  • Cata Velez-Ortega, PhD

    "Activity-dependent Plasticity of the Stereocilia Cytoskeleton in Cochlear Hair Cells"
    Wednesday, May 24, 2017

  • Tim McClintock, PhD

    "In Vivo Human Odorant Receptor Responses​​​​​​​"
    Wednesday, May 31, 2017

  • Steve Estus, PhD

    "Translating Alzheimer's genetic findings with SHIP1 to generate a novel Alzheimer’s pharmacologic agent​​​​​​​"
    Wednesday, August 30, 2017

  • Stefka Spassieva, PhD

    "Deoxysphingolipids as intermediates of taxane-induced peripheral neuropathy"
    Wednesday, September 6, 2017

  • Venkat Subramanian, PhD

    "Role of Calpain in Abdominal Aortic Aneurysms​​​​​​​"
    Wednesday, September 13, 2017

  • Suzanne Doolen, PhD

    "Spinal neuroimmune receptor C3aR and neuropathic pain​​​​​​​"
    Wednesday, September 20, 2017

2016 Grants in Progress

  • Mariana Nikolova-Karakashian, PhD

    Exploring IL-1B- glucocorticoid connections in liver and brain
    Wednesday, June 29, 2016

  • Ken Campbell, PhD

    "Potential new R21: Thick filament regulation of cardiac contractility"
    Wednesday, August 10, 2016

  • Joe Abisambra, PhD

    "Identification of the molecular mechanisms linking Alzheimer's disease, PERK, and mild repetitive head injury"
     Wednesday, September 28, 2016

2015 Grants in Progress

  • Brian Delisle, PhD

    "Circadian Rhythms and Arrhythmia Syndromes: Light and Reviewer 1 are Killers"
    Wednesday, December 16, 2015

  • Tim McClintock, PhD

    "Lhx2 Determines Odorant Receptor Expression Frequency in Mature Olfactory Sensory Neurons"
    Friday, December 11, 2015

  • Mariana  Nikolova-Karakashian, PhD

    "Mechanisms of cellular senescence in hepatocytes"
    Wednesday, October 7, 2015

  • Brad Taylor, PhD

     "Understanding the neural mechanisms by which Neuropeptide Y inhibits pain: Strategic response to study section review of R01 renewal for Years 11-15 with a score at the 27th percentile"
    Wednesday, September 16, 2015

  • Mariana Nikolova-Karakashian, PhD

    "Sphingolipids and impaired wound healing in diabetes"
    Wednesday, January 7, 2015

  • Brian Delisle, PhD

    "Cardiac circadian rhythms and cardiac arrhythmias"
    Wednesday, January 14, 2015

  • Samir Patel, PhD

    "Treatment of spinal cord injury with alternative biofuels as energy sources"
    Wednesday, January 21, 2015

  • Steve Estus, PhD

    "Exploring the jungle within - does your gut microbiome alter Alzheimer's disease risk?"
    Wednesday, April 1, 2015

  • Brian Delisle, PhD

     "Transcriptional regulation of Scn5a by the Molecular Clock, Or: Chronic jet lag can kill"
    Wednesday, June 10, 2015

2014 Grants in Progress

  • Sasha Rabchevsky, PhD

    "Gabapentin Management of Autonomic Dysreflexia after Spinal Cord Injury: Influences on Peripheral and Central Inflammation"
    Wednesday, January 15, 2014

  • Joe Abisambra, PhD

    "Manipulating ER Stress Pathways to Treat Tauopathies"
    Friday, January 22, 2014

  • Steve Estus, PhD

    "Human Genetics to Establish Research Significance / Genetics of Inflammation in Alzheimers"
    Wednesday, January 29, 2014

  • Gregory Frolenkov, PhD

     "Repair of the hair cell bundle"
    Wednesday, February 5, 2014

  • Melinda Wilson, PhD

    "DNA methylation in the aging brain: use it to lose it!"
    Wednesday, February 12, 2014

  • Joe Abisambra, PhD

    "The impact of the Tau-rpS6 association in the pathogenesis of Alzheimer’s disease"
    Wednesday, March 5, 2014

  • Gregory Frolenkov, PhD

    "Stereocilia bundle repair"
    Wednesday, March 12, 2014

  • John Gensel, PhD

     "The effect of age on spinal cord injury and neuroinflammation"
    Wednesday, April 9, 2014

  • Mariana Nikolova-Karakashian, PhD

    "The Biolipidome of Aging"
    Wednesday, April 16, 2014

  •  John Gensel, PhD

    "The role of macrophages in spinal cord injury...Round 3"
    Wednesday, May 7, 2014

  • Karin High, PhD

    "Neurogenic Amplification of Alcoholic Pancreatitis Pain"
    Wednesday, May 14, 2014

  • Ken Campbell, PhD

    "Human Heart Failure"
    Wednesday, July 9, 2014

  •  Moriel Vandsburger, PhD

    "Discussion of specific aims for non-contrast fibrosis imaging R01 proposal"
    Wednesday, July 16, 2014

  • Gregory Frolenkov, PhD

    "Nano-physiology of hair cell mechanotransduction. Part II"
    Wednesday, September 17, 2014

  • Tim McClinktock, PhD

    "Pharmacology of Receptors for Health-related Odorant-ligands"
    Wednesday, November 12, 2014

  • Joe Abisambra, PhD

    "The impact of the PERK pathway on tau-mediated toxicity: dealing with summary statements without harming your computer."
    Wednesday, December 3, 2014

  • Melinda Wilson, PhD

    "Altering gene expression in the aging brain"
    Wednesday, December 10, 2014

  • John Gensel, PhD

    "R01 resubmission plans: The role of macrophages and age in spinal cord injury"
    Wednesday, December 17, 2014

2013 Grants in Progress (GiPs)

  • Paco Andrade, PhD

    "Loss of eye muscle-specific myosin impacts extra-ocular muscle structure and function"
    Wednesday, October 23, 2013

  • Gregory Frolenkov, PhD

    "Nano-physiology of hair cell mechanotransduction"
    Wednesday, March 20, 2013

  • Jon Satin, PhD

    "I wanted to talk about our yellow fluorescent protein fused to L-type calcium channel knockin mice but they are taking too $%# long to breed & so I will discuss calmodulin mutations in infants with epilepsy &/or sudden cardiac arrest & how this new, exciting WiP has something to do with L-type Ca channels & you all can tell me which one of the other 999 binding partners of calmodulin might create areas of mutual benefit for potential funding"
    Wednesday, November 6, 2013

  • Tim McClintock, PhD

    "Mechanisms of Odorant Discrimination"
    Wednesday, November 20, 2013

  • John Gensel, PhD

    "Vacillating Macrophages and the Enigmatic SCI Environment"
    Wednesday, December 4, 2013

  • Moriel Vandsburger, PhD

    "Completely non-invasive imaging of myocardial fibrosis with MRI"
    Wednesday, December 11, 2013

  • Karyn Esser, PhD

    "Why does muscle weakness predict mortality?  A systems physiology question"
    Wednesday, December 18, 2013

Date Event Title
05/22/2024 Cancelled - Please Attend Barnstable Brown Diabetes Research Day
05/08/2024 Neurotoxicity of sphingoid bases
04/24/2024 De Novo Elastic Fiber Synthesis by Smooth Muscle Cells Differentiated from Sca1+ Progenitor Cells Following Aortic Dissection
04/10/2024 MyoAAV to the rescue: Our foray into new viral vectors & serotypes for doing really rad science
02/28/2024 Macrophage immunometabolism as a therapeutic target for TBI
02/21/2024 Identification of SR-BI as a scavenger of heme
02/14/2024 Neutral sphingomyelinase-2 in the steatotic liver: A novel role in regulating lipid droplet:mitochondria interaction and LD expansion.
02/07/2024 Digital PCR Machine Presentation
01/31/2024 What I did last summer: Antagonists for cigarette smoke odor
01/17/2024 Using the gut microbiome to treat skeletal muscle atrophy
01/10/2024 cGAS-STING Signaling in Macrophage Lipid Metabolism and Atherogenesis
12/06/2023 Nanophysiology of mechanotransduction in mammalian auditory hair cells
11/15/2023 Cell-specific allelic 'switching': APOE4,3,2, which 1 is best?
11/08/2023 Sildenafil to target brain capillary-specific mitochondrial function following mild blast traumatic brain injury
10/25/2023 Mitochondrial metabolism as a novel regulator of atherogenic lipoproteins
10/11/2023 Functional Interactions Between Lipoproteins and Protease Inhibitors in Atherosclerosis
09/27/2023 Antidiabetic GLP-1RA Exenatide: a potential chronotherapy for Alzheimer's disease in mice with diabetes?
09/13/2023 Exploring chromosomal vs. hormonal sex differences in spinal cord injury
08/30/2023 Cancelled
08/16/2023 Unlocking genetics to identify T cell regulators for Alzheimer's Disease
08/02/2023 Regeneration of elastic fibers in chronic Stanford type B aortic dissection
07/19/2023 Grant Outline: Circadian Regulation of Cardiac Electrophysiology
07/05/2023 Time-of-day specificity of anticancer drugs may be mediated by circadian regulation of the cell cycle
06/21/2023 Disruption of cerebral hemodynamics and brain connectome after mild traumatic brain injury
06/07/2023 The sphingosine-1-phosphate receptor 1 antagonist Ponesimod reduces TLR4-induced neuroinflammation and increases Aβ clearance
04/19/2023 Available
04/05/2023 Cancelled - No Speaker
03/29/2023 Cancelled - No Speaker
03/22/2023 WIPS, Predictors of cardiac growth
03/15/2023 Cancelled - No Speaker
03/08/2023 Cancelled - No Speaker
03/01/2023 Cancelled - No Speaker
02/22/2023 Axon growth in chronic spinal cord injury repair: Long-term effects of sustaining growth on functional recovery, regeneration, and neuronal health
02/15/2023 Enhanced formation and activation of the ABCG5 ABCG8 sterol transporter in the treatment of Sitosterolemia and hypercholesterolemia
02/08/2023 Cancelled - No Speaker