Mice with RAI have impaired phagocytic ability of phagocytes in sepsis. SR-BIfl/fl mice and SF1creSR-BIfl/fl mice were treated with CLP (25G, full ligation) for 17 h and then injected with 109 CFU/ml BODIPY-conjugated E. coli via i.p. After 1 hour, the mean fluorescence intensity (MFI) of E. coli in CD11b+ cells (A), macrophages (B) and neutrophils (C) in peritoneal fluids was analyzed with flow cytometry. n = 2-4. Data are means ± SE. Control represents mice without CLP and E. coli treatment.
Dr. Cheavar Blair in a lab

Cheavar Blair, PhD, completed his doctorate at the University of Kentucky College of Medicine in 2015. During his graduate training, he was impressed by UK’s supportive environment and attentive faculty – qualities that enticed him to return when a faculty position recently became available.

 

Gurpreet Dhaliwal

The UK College of Medicine is excited to welcome Gurpreet Dhaliwal, MD, as the visiting professor delivering this year’s Alpha Omega Alpha (AOA) Humanities Lecture. 

UK undergraduates on the steps

The 21st annual Posters-at-the-Capitol on March 2, 2023, will feature 14 University of Kentucky undergraduate students whose research addresses topics with important implications for issues in Kentucky, including community health, agricultural sustainability, renewable energy and public health and safety.

woman holding her hands up making a heart shape

The University of Kentucky’s ninth annual Healthy Hearts for Women Symposium will bring in nationally recognized experts to raise awareness about the dangers of heart disease and educate attendees on prevention techniques.

Dr. Susan Smyth pictured in pedway leading to BBSRB

The University of Kentucky College of Medicine lost an icon in the field of cardiovascular medicine, translational research, and medical education. Susan Smyth, MD, PhD, died of cancer on Dec. 31, 2022, at the age of 57.

Authors Martha Sim and Jeremy Wood presenting findings at ASH

Originally published September 25, 2022 at www.sciencedirect.com

By Martha M S Sim, Jeremy P Wood

Analia Loria Kinsey

Analia Loria Kinsey, PhD, is an associate professor in the UK College of Medicine Department of Pharmacology and Nutritional Sciences. She studies cardiovascular disease and strives to raise awareness about preventative measures and treatments by helping organize the college’s annual Healthy Hearts for Women Symposium.

College of medicine logo over white background

Our College of Medicine community,

Honoring Indigenous Peoples' Month

During Indigenous Peoples’ Month, the UK College of Medicine is highlighting historical figures who paved the way for an equitable future in medicine.
 

Alan Daugherty, PhD, DSc speaking at podium

A University of Kentucky researcher has received a prestigious honor recognizing his decades of work in cardiovascular health.

Alan Daugherty, PhD, DSc, was named the 2022 George Lyman Duff Memorial Lecturer at the American Heart Association’s (AHA) Scientific Sessions.

Scott Camerson, Jason Gill, and Greg Graf

Hundreds of researchers, students and guests attended the 24th University of Kentucky Cardiovascular Research Day at the Central Bank Center, an annual event that celebrates innovative research in cardiovascular health.

Donna Wilcock, PhD on Sept, 22, 2022.

Donna Wilcock, PhD, of the University of Kentucky’s Sanders-Brown Center on Aging (SBCoA) was awarded a $1.7 million National Institutes of Health grant for her lab’s exploration of adverse effects of two new Alzheimer’s disease drugs — aducanumab and lecanemab —​ which have been shown to slow the progression of cognitive decline.

Scott Gordon lab member photo
Abstract

Dennd5b plays a pivotal role in intestinal absorption of dietary lipids and is associated with body mass index in humans. This study examined the impact of whole-body Dennd5b deletion on plasma lipid concentrations, atherosclerosis, and hepatic lipid metabolism.

The renin angiotensin system and its therapeutic targets. ACE indicates angiotensin-converting enzyme; ACEi, ACE inhibitor; ARBs, angiotensin II type 1 receptor blockers; ARNI, angiotensin receptor neprilysin inhibitor; ASO, antisense oligonucleotides; AT1R, angiotensin II type 1 receptor; DRI=direct renin inhibitor and siRNA, small interfering RNA.

Originally Posted July 29, 2022: https://www.ahajournals.org/doi/10.1161/HYPERTENSIONAHA.122.18731

Gaurang Vaidya

When he was a cardiology fellow, Gaurang Vaidya, MD, faced a persistent question while providing care for heart failure patients – how much extra water is in the patient’s body?

Stained aortic tissue and sections of cell walls

Embryonic Heterogeneity of Smooth Muscle Cells in the Complex Mechanisms of Thoracic Aortic Aneurysms

Edaravone Attenuated Angiotensin II-Induced Atherosclerosis and Abdominal Aortic Aneurysms in Apolipoprotein E-Deficient Mice

Students in the inaugural cohort of UK's Undergraduate Summer Training in Cardiovascular Research program.

LEXINGTON, Ky. (July 21, 2021) — A new immersive summer research program at the University of Kentucky is helping to prepare the next generation of biomedical researchers.

Swimming is Alayna Benningfield's passion, but heart failure kept her out of the pool. After recovering her heart function with an LVAD, she is back in action.

LEXINGTON, Ky. (June 8, 2022) — In 2019, Alayna Benningfield was living her dream.