Cardiovascular Journal Club Archive of Previous Meetings

Date	Event Title	Speaker
12/06/2023	The Histone Methyltransferase SETDB2 Modulates Tissue Inhibitors of Metalloproteinase–Matrix Metalloproteinase Activity During Abdominal Aortic Aneurysm Development	Julianne Sharpe
11/29/2023	Directed evolution of a family of AAV capsid variants enabling potent muscle-directed gene delivery across species	Cheavar Blair
11/22/2023	Thanksgiving Break
11/15/2023	Single-Molecule Spatial Transcriptomics of Human Thoracic Aortic Aneurysms Uncovers Calcification-Related CARTPT-Expressing Smooth Muscle Cells	Sohei Ito
11/08/2023	Prolonged QT intervals in mice with cardiomyocyte-specific deficiency of the molecular clock	Brian Delisle
11/01/2023	Cell-autonomous regulation of complement C3 by factor H limits macrophage efferocytosis and exacerbates atherosclerosis	Shu Liu
10/25/2023	Resveratrol intervention attenuates chylomicron secretion via repressing intestinal FXR-induced expression of scavenger receptor SR-B1	Olivia Hage
10/18/2023	Hepatic SREBP signaling requires SPRING to govern systemic lipid metabolism in mice and humans	Anna Mead
10/11/2023	A HIF independent oxygen-sensitive pathway for controlling cholesterol synthesis	Gregory Graf
10/04/2023	Pharmacological treatment with FGF21 strongly improves plasma cholesterol metabolism to reduce atherosclerosis	Zachary Kipp
09/27/2023	The DWORF micropeptide enhances contractility and prevents heart failure in a mouse model of dilated cardiomyopathy	Garrett Elmore
09/20/2023	Intracellular tPA–PAI-1 interaction determines VLDL assembly in hepatocytes	Alex Pettey
09/13/2023	Hepatic nonvesicular cholesterol transport is critical for systemic lipid homeostasis	Preetha Shridas
09/06/2023	Severe hypertriglyceridemia caused by Gpihbp1 deficiency facilitates vascular remodeling through increasing endothelial activation and oxidative stress	Ryan Temel
08/30/2023	Platelets exacerbate cardiovascular inflammation in a murine model of Kawasaki disease vasculitis	Shayan Mohammadmoradi
08/30/2023	Blair Lab	TBD
08/23/2023	Extracellular vesicle-based interorgan transport of mitochondria from energetically stressed adipocytes	Congqing Wu
08/23/2023	Alsiraj Lab	TBD
04/25/2023	Sustained alternate-day fasting potentiates doxorubicin cardiotoxicity	Cheavar Blair
04/18/2023	STING activation in platelets aggravates septic thrombosis by enhancing platelet activation and granule secretion	Jian Cui, PhD
04/11/2023	Atherosclerosis Regression and Cholesterol Efflux in Hypertriglyceridemic Mice	Lei Cai
04/04/2023	Endothelial HDAC1-ZEB2-NuRD Complex Drives Aortic Aneurysm and Dissection Through Regulation of Protein S-Sulfhydration	Sohei Ito
03/28/2023	Ablation of CaMKIId oxidation by CRISPR-Cas9 base editing as a therapy for cardiac disease	Nicholas McVay
03/21/2023	CCN2 deficiency in smooth muscle cells triggers cell reprogramming and aggravates aneurysm development	Naofumi Amioka
03/14/2023	No Meeting, Spring Break
03/07/2023	Inhibition of ATG3 ameliorates liver steatosis by increasing mitochondrial function	Mikala Zelows
02/28/2023	Light modulates glucose metabolism by a retina-hypothalamus-brown adipose tissue axis	Mina Lin
02/21/2023	MGAT2 inhibitor decreases liver fibrosis and inflammation in murine NASH models and reduces body weight in human adults with obesity	Gregory Graf
02/14/2023	A hepatokine derived from the ER protein CREBH promotes triglyceride metabolism by stimulating lipoprotein lipase activity	Raj Neupane
02/07/2023	Platelet olfactory receptor activation limits platelet reactivity and growth of aortic aneurysms	Shu Liu
01/31/2023	Slowing Heart Rate Protects Against Pathological Cardiac Hypertrophy	Brian Delisle
01/24/2023	Drug Targeting of Plasminogen Activator Inhibitor-1 Inhibits Metabolic Dysfunction and Atherosclerosis in a Murine Model of Metabolic Syndrome	Alex Pettey
01/17/2023	ILRUN Promotes Atherosclerosis Through LipidDependent and Lipid-Independent Factors	Gregory Graf
11/29/2022	Dietary lipids inhibit mitochondria transfer to macrophages to divert adipocyte-derived mitochondria into the blood
11/22/2022	Nonmyocyte ERK1/2 signaling contributes to load-induced cardiomyopathy in Marfan mice	Bryana Levitan