Date Event Title Speaker
10/13/2015 "Sympathetic Neuro-adipose Connections Mediate Leptin-Driven Lipolysis" Gregory Graf, PhD
10/06/2015 "New CETP inhibitor K-312 reduces PCSK9 expression: a potentional effect on LDL cholesterol metabolism" Reiya Hayden
09/29/2015 "Perhexiline activates KLF14 and reduces atherosclerosis by modulating ApoA-I production" Jing Liu
09/22/2015 "The Bile Acid Chenodeoxycholic Acid Increases Human Brown Adipose Tissue Activity" Heather Norman
09/15/2015 "The adipokine Retnla modulates cholesterol homeostasis in hyperlipidemic mice" Nate Helsley
09/08/2015 "Development and rescue of human familial hypercholesterolaemia in a xenograt mouse model" Joe Layne, PhD
09/08/2015 Weekly CVRC Journal Club Begins
04/28/2015 "Fibroblast Growth Factor 21 Prevents Atherosclerosis by Suppression of Hepatic Sterol Regulatory Element-Binding Protein-2 and Induction of Adiponectin in Mice" Heather Norman
04/21/2015 "Interplay between FGF21 and insulin action in the liver regulates metabolism" Yuhuan Wang
04/14/2015 "Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance" Sonja Pijut
04/07/2015 "Intestinal farnesoid X receptor signaling promotes nonalcoholic fatty liver disease" Jianing Li
03/31/2015 "Dimorphic Effects of Transforming Growth Factor-β Signaling During Aortic Aneurysm Progression in Mice Suggest a Combinatorial Therapy for Marfan Syndrome" Alan Daugherty, PhD, DSc
03/24/2015 "Cholesterol-lowering drugs cause dissolution of cholesterol crystals and disperse Kupffer cell crown-like structures during resolution of NASH." Gregory Graf, PhD
03/17/2015 UK Spring Break No Journal Club
03/03/2015 "NF-kB Directs Dynamic Super Enhancer Formation in Inflammation and Atherogenesis" Sangderk Lee, PhD
02/24/2015 "MAFG Is a Transcriptional Repressor of Bile Acid Synthesis and Metabolism" Nate Helsley
02/17/2015 Cancelled due to weather
02/10/2015 "Alginic acid cell entrapment: a novel method for measuring in vivo macrophage cholesterol homeostasis" Joe Layne, PhD
02/03/2015 "The TMAO-Generating Enzyme Flavin Monooxygenase 3 Is a Central Regulator of Cholesterol Balance" Gregory Graf, PhD
01/27/2015 "Angiotensin II Mobilizes Spleen Monocytes to Promote the Development of Abdominal Aortic Aneurysm in Apoe−/− Mice" Sean Thatcher, PhD
12/09/2014 New Therapy via Targeting Androgen Receptor in Monocytes/Macrophages to Battle Atherosclerosis Yasir Al-Siraj
12/02/2014 No Journal Club
11/25/2014 Discovery of a Class of Endogenous Mammalian Lipids with Anti-Diabetic and Anti-inflammatory Effects Heather Norman
11/18/2014 Adenosine Activates Brown Adipose Tissue and Recruits Beige Adipocytes via A2A Receptors Margaret Murphy
11/11/2014 Induction of Atherosclerosis in Mice and Hamsters Without Germline Genetic Engineering Ryan Temel
11/04/2014 Metabolic Dysfunction Drives a Mechanistically Distinct Proinflammatory Phenotype in Adipose Tissue Macrophages Yu Wang
10/28/2014 Retinoic Acid-related Orphan Receptor α Regulates Diurnal Rhythm and Fasting Induction of Sterol 12α-Hydroxylase in Bile Acid Synthesis Sonja Pijut
10/21/2014 Proposed Principles and Guidelines for Reporting Preclinical Research Alan Daugherty
10/14/2014 SUMOylation-Dependent LRH-1/PROX1 Interaction Promotes Atherosclerosis by Decreasing Hepatic Reverse Cholesterol Transport Gregory Graf
10/07/2014 Adipocyte Inflammation Is Essential for Healthy Adipose Tissue Expansion and Remodeling Nate Helsley
09/30/2014 Obesity activates a program of lysosomal-dependent lipid metabolism in adipose tissue macrophages independently of classic activation Jianing Li
09/23/2014 Aldosterone Promotes Vascular Remodeling by Direct Effects on Smooth Muscle Cell MIneralocorticoid Receptors Robin Shoemaker
09/16/2014 Intestine specific MTP deficiency with global ACAT2 gene ablation lowers acute cholesterol absorption with chylomicrons and high density lipoproteins Joseph Layne
05/06/2014 TBD Sean Thatcher
04/29/2014 TBD Sonja Pujit