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Abstract 

Heparin-binding EGF-like growth factor (HB-EGF) is a representative EGF family member that interacts with EGFR under diverse stress environment. Previously, we reported that the HB-EGF-targeting using antisense oligonucleotide (ASO) effectively suppressed an aortic aneurysm in the vessel wall and circulatory lipid levels. In this study, we further examined the effects of the HB-EGF ASO administration on the development of hyperlipidemia-associated atherosclerosis using an atherogenic mouse model.

METHODS AND RESULTS:

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J Clin Invest. 2019 Feb 1;129(2):496-498. doi: 10.1172/JCI125958.
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The 5th Annual Healthy Hearts for Women Symposium will take place this Friday, February 1st. This year's symposium features four distinguished faculty from across the nation and Canada. The event begins at 8:30 am with registration and breakfast in Pavilion A Auditorium in the University of Kentucky Medical Center.

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The University of Kentucky Saha Cardiovascular Research Center is pleased to announce that applications are being accepted for the Saha Awards. The Saha Awards are given to encourage and support staff and students with an interest in and dedication to cardiovascular medicine. Each award includes an unrestricted $1000 prize, a certificate and recognition at the University of Kentucky Gill Heart Institute Cardiovascular Research Day held on September 20, 2019 at the Gatton Student Center.

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2018 Saha Awards

2018 Winners:
Eastern Kentucky Nursing Student Award – Nikita Tamara Watts
University of Kentucky Nursing Student Award – Jessica Harman
Medical Student Award – Rahul Annabathula

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Applications are now being accepted for the 2019 Saha Awards.

 The Saha Awards are given to encourage and support staff and students with an interest in and dedication to cardiovascular medicine. Each award includes an unrestricted $1000 prize, a certificate and recognition at the University of Kentucky Gill Heart Institute Cardiovascular Research Day held on September 20, 2019 at the Gatton Student Center.

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The 11th Annual Hardin Award was presented to Andrew Hernandez, an administrative staff member in the Department of Physiology, on December 14, 2018 during the Physiology Holiday Party at Kroger Field's Woodford Reserve Club.

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Moua Yang, Andaleb Kholmukhamedov, Marie L. Schulte, Brian C. Cooley, Na’il O. Scoggins, Jeremy P. Wood*, Scott J. Cameron, Craig N. Morrell, Shawn M. Jobe, and Roy L. Silverstein 

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As a child, Chris Waters was always curious about how things worked. His inquiring mind led him on a path from chemical engineering to biomedical engineering to his current work on a dangerous condition called acute respiratory distress syndrome (ARDS).

The mortality rate for this acute lung injury is high — almost 40 percent of ARDS patients die. Appropriate mechanical ventilation makes a huge difference in their prognosis. 

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November 28, 2018 - Friends, family, and colleagues joined together to honor three retiring, esteemed UK faculty members. A retirement celebration was held on November 28 at the Hillary J. Boone Center to honor the careers and celebrate the retirement of Drs. Marcielle De Beer, Sandy Legan, and David Randall.

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Please join us for a retirement celebration on Wednesday, November 28, for three exceptional UK, College of Medicine faculty members. All are invited to this event, which will celebrate and recognize the years of service for Drs. Marcielle De Beer, Sandy Legan, and David Randall. This event will be held at the Hillary J. Boone Center on the main campus beginning at 3:00 p.m., no RSVP required.

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Janet R. Manning, Lakshman Chelvarajan**, Bryana M. Levitan, Catherine N. Withers, Prabhakara R. Nagareddy, Christopher M. Haggerty, Brandon K. Fornwalt, Erhe Gao, Himi Tripathi**, Ahmed Abdel-Latif*, Douglas A. Andres, Jonathan Satin

Abstract

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November 19, 2018 - The University of Kentucky has been awarded grants totaling over $160,000 by the American Heart Association.

These pre-doctoral grants will fund research into cardiovascular disease and health. Three graduate students have been awarded $26,844 per year for the next two years.

The grants have been awarded to:

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 Graduate students at the University of Kentucky have been awarded research grants totaling over $80,000 by the American Heart Association.

These grants will fund three graduate student researchers within the Department of Physiology and Saha Cardiovascular Research Center in studying apporaches to cardiovascular dieseases and health.

The grants are:

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Dr. Tannock joined UK in 2004 and is now the chief of endocrinology in the Department of Internal Medicine as well as the associate director of the Barnstable Brown Diabetes Center. Endocrinologists study and treat hormone-related diseases, such as diabetes and thyroid disease. Some of Dr. Tannock's clinical interests include diabetes and insulin resistance, cholesterol disorders and transgender medicine. Barnstable Brown is one of the few centers in Kentucky to offer hormonal management therapies to transgender individuals.