Vice Chair for Research: Derek B. Allison, MD

Derek Allison, MD

Positions Held:
  • Associate Professor
  • Vice Chair for Research
  • Assistant Director & Quality Officer, Biospecimen Procurement & Translational Pathology (BPTP) Shared Resource Facility

Vice Chair for Basic Science Research: Peter Nelson, MD, PhD

Peter Nelson, MD, PhD

Positions Held:
  • Professor
  • Director - Neuropathology
  • Vice Chair for Basic Science Research

Second Annual Department Research Day

Research Day Awards:


Excellence in Clinical Research Award: Faisal Hassan

Follicular (FLCN) Alterations in Thyroid Carcinoma: Incidence, Significance, and Extraordinary Role as a Driver Gene in an Aggressive Mixed Papillary and Oncocytic Thyroid Carcinoma

Faisal A Hassan MD, Robert James McDonald DO, Julie Dueber MD, Therese J Bocklage, MD, Derek B Allison MD


Excellence in Research Presentation Award: Hafsa Nebbache

Novel, Adult-Learning-Based Pathology Core Curriculum (PCC): Components, Correlations and Critiques of a Program Now in Place 4.5 Years

Hafsa Nebbache, Aaron Daniel Shmookler, Justin Rueckert, Sahar Nozad, Derek B Allison, Robert J Macdonald, Leanna Brignola, Therese Bocklage, Janna Neltner


Congratulations to all!

USCAP 2024 Presenters

CAP 2023 Presenters

Recent Publication Selections

2024 Publications

Section 1

Bachert SE, Di J, Zhang S, Short HE, Piecoro DW, McDonald RJ, Myint ZW, Hensley PJ, Allison DB. TRPS1 expression in primary and metastatic prostatic adenocarcinoma, muscle invasive bladder urothelial carcinoma, and breast carcinoma: Is TRPS1 truly specific and sensitive for a breast primary? Hum Pathol. 2024 Jan;143:42-49. doi: 10.1016/j.humpath.2023.11.012. Epub 2023 Dec 3. PMID: 38052269; PMCID: PMC10842859.

Kapoor AK, Ellis CS, Pandey D, Allison DB, Myint ZW. Case report: Enfortumab vedotin induced refractory DKA and multi organ failure - a rare fatal adverse event. Front Oncol. 2024 Feb 15;14:1332478. doi: 10.3389/fonc.2024.1332478. PMID: 38425338; PMCID: PMC10902430.

Do J, Arshad T, Ferreira JE, Yenwongfai LN, Nebbache H, Allison DB, Piecoro DW, Kesler MV. An isolated sacral promyelocytic sarcoma in a child: A rare case report with emphasis on cytomorphology. Diagn Cytopathol. 2024 Mar 17. doi: 10.1002/dc.25304. Epub ahead of print. PMID: 38494827.

Arshia A, Hassan FA, Hensley PJ, Allison DB. Urinary tract cytology showing variant morphology and divergent differentiation. Cytopathology. 2024 Mar;35(2):199-212. doi: 10.1111/cyt.13322. Epub 2023 Nov 2. PMID: 37919868.

Hutchcraft ML, Zhang S, Lin N, Pickarski JC, Belcher EA, Wei S, Bocklage T, Miller RW, Villano JL, Cavnar MJ, Kim J, Arnold SM, Ueland FR, Kolesar JM. Feasibility and Clinical Utility of Reporting Hereditary Cancer Predisposition Pathogenic Variants Identified in Research Germline Sequencing: A Prospective Interventional Study. JCO Precis Oncol. 2024 Jan;8:e2300266. doi: 10.1200/PO.23.00266. PMID: 38295319; PMCID: PMC10843325.

Bocklage T, Cornea V, Hickey C, Miller J, Moss J, Chambers M, Bachert SE. Ki-67 Testing in Breast Cancer: Assessing Variability With Scoring Methods and Specimen Types and the Potential Subsequent Impact on Therapy Eligibility. Appl Immunohistochem Mol Morphol. 2024 Mar 1;32(3):119-124. doi: 10.1097/PAI.0000000000001188. Epub 2024 Mar 7. PMID: 38450704.

Di J, Hickey C, Bumgardner C, Yousif M, Zapata M, Bocklage T, Balzer B, Bui MM, Gardner JM, Pantanowitz L, Qasem SA. Utility of artificial intelligence in a binary classification of soft tissue tumors. J Pathol Inform. 2024 Feb 15;15:100368. doi: 10.1016/j.jpi.2024.100368. PMID: 38496781; PMCID: PMC10940995.

Brasher M, Virodov A, Raffay TM, Bada HS, Cunningham MD, Bumgardner C, Abu Jawdeh EG. Predicting Extubation Readiness in Preterm Infants Utilizing Machine Learning: A Diagnostic Utility Study. J Pediatr. 2024 Mar 30:114043. doi: 10.1016/j.jpeds.2024.114043. Epub ahead of print. PMID: 38561049.

Niedowicz DM, Gollihue JL, Weekman EM, Phe P, Wilcock DM, Norris CM, Nelson PT. Using digital pathology to analyze the murine cerebrovasculature. J Cereb Blood Flow Metab. 2024 Apr;44(4):595-610. doi: 10.1177/0271678X231216142. Epub 2023 Nov 21. PMID: 37988134; PMCID: PMC10981399.

Chung M, Carter EK, Veire AM, Dammer EB, Chang J, Duong DM, Raj N, Bassell GJ, Glass JD, Gendron TF, Nelson PT, Levey AI, Seyfried NT, McEachin ZT. Cryptic exon inclusion is a molecular signature of LATE-NC in aging brains. Acta Neuropathol. 2024 Feb 3;147(1):29. doi: 10.1007/s00401-023-02671-0. PMID: 38308693; PMCID: PMC10838224.

Foley KE, Winder Z, Sudduth TL, Martin BJ, Nelson PT, Jicha GA, Harp JP, Weekman EM, Wilcock DM. Alzheimer's disease and inflammatory biomarkers positively correlate in plasma in the UK-ADRC cohort. Alzheimers Dement. 2024 Feb;20(2):1374-1386. doi: 10.1002/alz.13485. Epub 2023 Nov 27. PMID: 38011580; PMCID: PMC10917006.

Nelson PT, Sziraki A, Cao J. Response letter: Complexities in pericyte markers. Neuropathol Appl Neurobiol. 2024 Apr;50(2):e12975. doi: 10.1111/nan.12975. PMID: 38566360.

Katsumata Y, Fardo DW, Shade LMP, Wu X, Karanth SD, Hohman TJ, Schneider JA, Bennett DA, Farfel JM, Gauthreaux K, Mock C, Kukull WA, Abner EL, Nelson PT; Alzheimer's Disease Neuroimaging Initiative; National Alzheimer's Coordinating Center. Genetic associations with dementia-related proteinopathy: Application of item response theory. Alzheimers Dement. 2024 Mar 9. doi: 10.1002/alz.13741. Epub ahead of print. PMID: 38460116.

Katsumata Y, Wu X, Aung KZ, Gauthreaux K, Mock C, Forrest SL, Kovacs GG, Nelson PT. Pathologic correlates of aging-related tau astrogliopathy: ARTAG is associated with LATE-NC and cerebrovascular pathologies, but not with ADNC. Neurobiol Dis. 2024 Feb;191:106412. doi: 10.1016/j.nbd.2024.106412. Epub 2024 Jan 19. PMID: 38244935; PMCID: PMC10892903.

Geleta U, Prajapati P, Bachstetter A, Nelson PT, Wang WX. Sex-Biased Expression and Response of microRNAs in Neurological Diseases and Neurotrauma. Int J Mol Sci. 2024 Feb 24;25(5):2648. doi: 10.3390/ijms25052648. PMID: 38473893; PMCID: PMC10931569.

Kraner SD, Sompol P, Prateeptrang S, Promkan M, Hongthong S, Thongsopha N, Nelson PT, Norris CM. Development of a monoclonal antibody specific for a calpain-generated ∆48 kDa calcineurin fragment, a marker of distressed astrocytes. J Neurosci Methods. 2024 Feb;402:110012. doi: 10.1016/j.jneumeth.2023.110012. Epub 2023 Nov 19. PMID: 37984591; PMCID: PMC10841921.

Gauthreaux K, Kukull WA, Nelson KB, Mock C, Chen YC, Chan KCG, Fardo DW, Katsumata Y, Abner EL, Nelson PT. Different cohort, disparate results: Selection bias is a key factor in autopsy cohorts. Alzheimers Dement. 2024 Jan;20(1):266-277. doi: 10.1002/alz.13422. Epub 2023 Aug 17. PMID: 37592813; PMCID: PMC10843760.

Bao WD, Pang P, Zhou XT, Hu F, Xiong W, Chen K, Wang J, Wang F, Xie D, Hu YZ, Han ZT, Zhang HH, Wang WX, Nelson PT, Chen JG, Lu Y, Man HY, Liu D, Zhu LQ. Correction: Loss of ferroportin induces memory impairment by promoting ferroptosis in Alzheimer's disease. Cell Death Differ. 2024 Apr 4. doi: 10.1038/s41418-024-01290-w. Epub ahead of print. Erratum for: Cell Death Differ. 2021 May;28(5):1548-1562. PMID: 38575681.

Nelson PT, Fardo DW, Wu X, Aung KZ, Cykowski MD, Katsumata Y. Limbic-predominant age-related TDP-43 encephalopathy (LATE-NC): Co-pathologies and genetic risk factors provide clues about pathogenesis. J Neuropathol Exp Neurol. 2024 Apr 13:nlae032. doi: 10.1093/jnen/nlae032. Epub ahead of print. PMID: 38613823.

Schilling J, Rudy M, Lima F, Richards D, Sawaya P, Rao M. Chronic Shoulder Pain in a Patient Receiving Maintenance Dialysis: A Quiz. Am J Kidney Dis. 2024 Apr;83(4):A13-A16. doi: 10.1053/j.ajkd.2023.09.022. PMID: 38519245.

2023 Publications

Section 1

Conroy LR, Clarke HA, Allison DB, Valenca SS, Sun Q, Hawkinson TR, Young LEA, Ferreira JE, Hammonds AV, Dunne JB, McDonald RJ, Absher KJ, Dong BE, Bruntz RC, Markussen KH, Juras JA, Alilain WJ, Liu J, Gentry MS, Angel PM, Waters CM, Sun RC. Spatial metabolomics reveals glycogen as an actionable target for pulmonary fibrosis. Nat Commun. 2023 May 13;14(1):2759. doi: 10.1038/s41467-023-38437-1. PMID: 37179348; PMCID: PMC10182559.

Castle JT, Levy BE, Allison DB, Rodeberg DA, Rellinger EJ. Pediatric Rhabdomyosarcomas of the Genitourinary Tract. Cancers (Basel). 2023 May 22;15(10):2864. doi: 10.3390/cancers15102864. PMID: 37345202; PMCID: PMC10216134.

Liu J, Zhao Y, He D, Jones KM, Tang S, Allison DB, Zhang Y, Chen J, Zhang Q, Wang X, Li C, Wang C, Li L, Liu X. A kinome-wide CRISPR screen identifies CK1α as a target to overcome enzalutamide resistance of prostate cancer. Cell Rep Med. 2023 Apr 18;4(4):101015. doi: 10.1016/j.xcrm.2023.101015. PMID: 37075701; PMCID: PMC10140619.

Li C, Allison DB, He D, Mao F, Wang X, Rychahou P, Imam IA, Kong Y, Zhang Q, Zhang Y, Liu J, Wang R, Rao X, Wu S, Evers BM, Shao Q, Wang C, Li Z, Liu X. Phosphorylation of AHR by PLK1 promotes metastasis of LUAD via DIO2-TH signaling. PLoS Genet. 2023 Nov 21;19(11):e1011017. doi: 10.1371/journal.pgen.1011017. PMID: 37988371; PMCID: PMC10662729.

Myint ZW, Chahine Z, Jayswal R, Bachert E, McDonald RJ, Strup SE, James AC, Hensley PJ, Allison DB. Association of CD47 Expression with Clinicopathologic Characteristics and Survival Outcomes in Muscle Invasive Bladder Cancer. J Pers Med. 2023 May 24;13(6):885. doi: 10.3390/jpm13060885. PMID: 37373873; PMCID: PMC10301952.

Cavanaugh AM, Raparti L, Bhurgri M, Herrington A, Holladay C, Arora V, Spicer KB, Thoroughman DA, Winter K. Characteristics of Decedents With COVID-19-Related Mortality in Kentucky, July 1-August 13, 2021. Public Health Rep. 2023 May-Jun;138(3):526-534. doi: 10.1177/00333549231155867. Epub 2023 Mar 16. PMID: 36927290; PMCID: PMC10020852.

Bachert SE, Cornea V, Bocklage T. Adenosquamous proliferation in radial sclerosing lesions: Histologic spectrum and key features in systematic review of 247 lesions. Breast. 2023 Oct;71:99-105. doi: 10.1016/j.breast.2023.08.002. Epub 2023 Aug 7. PMID: 37566996; PMCID: PMC10432801.

Levy BE, Castle JT, Virodov A, Wilt WS, Bumgardner C, Brim T, McAtee E, Schellenberg M, Inaba K, Warriner ZD. Artificial intelligence evaluation of focused assessment with sonography in trauma. J Trauma Acute Care Surg. 2023 Nov 1;95(5):706-712. doi: 10.1097/TA.0000000000004021. Epub 2023 May 11. PMID: 37165477.

Tolan NV, Krasowski MD, Mathias PC, Wiencek JR, Babic N, Chai PR, Chambliss AB, Choucair I, Demetriou CA, Erickson TB, Feldhammer M, French D, Hayes BD, Kang P, El-Khoury JM, Knezevic CE, Monte A, Nerenz RD, Okorodudu AO, Roper SM, Saitman A, Thiriveedhi V, Uljon SN, Vest A, Woodworth A, Yu M, Melanson SEF. Cannabis positivity rates in 17 emergency departments across the United States with varying degrees of marijuana legalization. Clin Toxicol (Phila). 2023 Apr;61(4):248-259. doi: 10.1080/15563650.2023.2177552. PMID: 37129223; PMCID: PMC10793079.

Gal J, Vary C, Gartner CA, Jicha GA, Abner EL, Ortega YS, Choucair I, Wilcock DM, Nelson R, Nelson P. Exploratory mass spectrometry of cerebrospinal fluid from persons with autopsy-confirmed LATE-NC. Res Sq [Preprint]. 2023 Aug doi: 10.21203/ PMID: 37674727; PMCID: PMC10479397.

Bruno MEC, Mukherjee S, Sturgill JL, Cornea V, Yeh P, Hawk GS, Saito H, Starr ME. PAI-1 as a critical factor in the resolution of sepsis and acute kidney injury in old age. Front Cell Dev Biol. 2024 Jan 18;11:1330433. doi: 10.3389/fcell.2023.1330433. PMID: 38304613; PMCID: PMC10830627.

Chung R, Garratt J, Remer EM, Navin P, Blake MA, Taffel MT, Hackett CE, Sharbidre KG, Tu W, Low G, Bara M, Carney BW, Corwin MT, Campbell MJ, Lee JT, Lee CY, Dueber JC, Shehata MA, Caoili EM, Schieda N, Elsayes KM. Adrenal Neoplasms: Lessons from Adrenal Multidisciplinary Tumor Boards. Radiographics. 2023 Jul;43(7):e220191. doi: 10.1148/rg.220191. PMID: 37347698.

Palaniyandi S, Kumari R, Strattan E, Huang T, Kohler K, Du J, Jabbour N, Kesler M, Hildebrandt GC. Role of Defibrotide in the Prevention of Murine Model Graft-versus-Host Disease after Allogeneic Hematopoietic Cell Transplantation. Transplant Cell Ther. 2023 Oct;29(10):608.e1-608.e9. doi: 10.1016/j.jtct.2023.07.023. Epub 2023 Jul 28. PMID: 37517613.

Palaniyandi S, Strattan E, Kumari R, Mysinger M, Hakim N, Kesler MV, Apatira M, Bittencourt F, Wang L, Jia Z, Gururaja TL, Hill RJ, Hildebrandt GC. Combinatorial inhibition of Tec kinases BTK and ITK is beneficial in ameliorating murine sclerodermatous chronic graft versus host disease. Bone Marrow Transplant. 2023 Aug;58(8):924-935. doi: 10.1038/s41409-023-02001-8. Epub 2023 May 9. PMID: 37160943.

Hiemenz MC, Kaur J, Kuang Z, Huang RSP, Harries L, Metzger D, Schiavone K, Millis SZ, Lin DI, Lechpammer M, Decker B, Mata DA, Reddy A, Parke M, Lee EY, Cui X, Iwenofu OH, Buehler D, Henderson L, Baldwin EM, Boikos SA, Ramkissoon SH, Smith SC. POU2AF3-rearranged sarcomas: A novel tumor defined by fusions of EWSR1 or FUS to a gene formerly designated COLCA2. Genes Chromosomes Cancer. 2023 Aug;62(8):460-470. doi: 10.1002/gcc.23136. Epub 2023 Mar 31. PMID: 36862145.

Thapa P, Jiang H, Ding N, Hao Y, Alshahrani A, Lee EY, Fujii J, Wei Q. Loss of Peroxiredoxin IV Protects Mice from Azoxymethane/Dextran Sulfate Sodium-Induced Colorectal Cancer Development. Antioxidants (Basel). 2023 Mar 9;12(3):677. doi: 10.3390/antiox12030677. PMID: 36978925; PMCID: PMC10045277.

Ferreira JE, Mbagwu E, Lee EY, Shelman NR, Allison DB. Cytopathological features of gastroesophageal junction adenocarcinoma with enteroblastic differentiation and histopathological correlation. Cytopathology. 2023 May;34(3):250-253. doi: 10.1111/cyt.13198. Epub 2022 Dec 24. PMID: 36524296.

Reed RG, Presnell SR, Al-Attar A, Lutz CT, Segerstrom SC. Life stressors and immune aging: Protective effects of cognitive reappraisal. Brain Behav Immun. 2023 May;110:212-221. doi: 10.1016/j.bbi.2023.02.018. Epub 2023 Mar 8. PMID: 36893924; PMCID: PMC10106412.

Reed RG, Hillmann AR, Presnell SR, Al-Attar A, Lutz CT, Segerstrom SC. Lifespan socioeconomic context is associated with cytomegalovirus and late-differentiated CD8+ T and NK cells: Initial results in older adults. Psychosom Med. 2023 Nov 16. doi: 10.1097/PSY.0000000000001267. Epub ahead of print. PMID: 37982534.

Section 2

Lu Z, Zhang M, Lee J, Sziraki A, Anderson S, Zhang Z, Xu Z, Jiang W, Ge S, Nelson PT, Zhou W, Cao J. Tracking cell-type-specific temporal dynamics in human and mouse brains. Cell. 2023 Sep 28;186(20):4345-4364.e24. doi: 10.1016/j.cell.2023.08.042. PMID: 37774676; PMCID: PMC10545416.

Nelson PT, Schneider JA, Jicha GA, Duong MT, Wolk DA. When Alzheimer's is LATE: Why Does it Matter? Ann Neurol. 2023 Aug;94(2):211-222. doi: 10.1002/ana.26711. Epub 2023 Jun 12. PMID: 37245084; PMCID: PMC10516307.

Katsumata Y, Fardo DW, Shade LMP; Alzheimer’s Disease Genetics Consortium; Nelson PT. LATE-NC risk alleles (in TMEM106B, GRN, and ABCC9 genes) among persons with African ancestry. J Neuropathol Exp Neurol. 2023 Aug 21;82(9):760-768. doi: 10.1093/jnen/nlad059. PMID: 37528055; PMCID: PMC10440720.

Nelson PT, Lee EB, Cykowski MD, Alafuzoff I, Arfanakis K, Attems J, Brayne C, Corrada MM, Dugger BN, Flanagan ME, Ghetti B, Grinberg LT, Grossman M, Grothe MJ, Halliday GM, Hasegawa M, Hokkanen SRK, Hunter S, Jellinger K, Kawas CH, Keene CD, Kouri N, Kovacs GG, Leverenz JB, Latimer CS, Mackenzie IR, Mao Q, McAleese KE, Merrick R, Montine TJ, Murray ME, Myllykangas L, Nag S, Neltner JH, Newell KL, Rissman RA, Saito Y, Sajjadi SA, Schwetye KE, Teich AF, Thal DR, Tomé SO, Troncoso JC, Wang SJ, White CL 3rd, Wisniewski T, Yang HS, Schneider JA, Dickson DW, Neumann M. LATE-NC staging in routine neuropathologic diagnosis: an update. Acta Neuropathol. 2023 Feb;145(2):159-173. doi: 10.1007/s00401-022-02524-2. Epub 2022 Dec 13. PMID: 36512061; PMCID: PMC9849315.

Nelson RS, Abner EL, Jicha GA, Schmitt FA, Di J, Wilcock DM, Barber JM, Van Eldik LJ, Katsumata Y, Fardo DW, Nelson PT. Neurodegenerative pathologies associated with behavioral and psychological symptoms of dementia in a community-based autopsy cohort. Acta Neuropathol Commun. 2023 Jun 2;11(1):89. doi: 10.1186/s40478-023-01576-z. PMID: 37269007; PMCID: PMC10236713.

Kloske CM, Gearon MD, Weekman EM, Rogers C, Patel E, Bachstetter A, Nelson PT, Wilcock DM. Association between APOE genotype and microglial cell morphology. J Neuropathol Exp Neurol. 2023 Jun 20;82(7):620-630. doi: 10.1093/jnen/nlad031. PMID: 37087107; PMCID: PMC10280358.

Ighodaro ET, Shahidehpour RK, Bachstetter AD, Abner EL, Nelson RS, Fardo DW, Shih AY, Grant RI, Neltner JH, Schmitt FA, Jicha GA, Kryscio RJ, Wilcock DM, Van Eldik LJ, Nelson PT. A neuropathologic feature of brain aging: multi-lumen vascular profiles. Acta Neuropathol Commun. 2023 Aug 28;11(1):138. doi: 10.1186/s40478-023-01638-2. PMID: 37641147; PMCID: PMC10464008.

Corriveau-Lecavalier N, Botha H, Graff-Radford J, Switzer AR, Przybelski SA, Wiste HJ, Murray ME, Reichard RR, Dickson DW, Nguyen AT, Ramanan VK, McCarter SJ, Boeve BF, Machulda MM, Fields JA, Stricker NH, Nelson PT, Grothe MJ, Knopman DS, Lowe VJ, Petersen RC, Jack CR Jr, Jones DT. A limbic-predominant amnestic neurodegenerative syndrome associated with TDP-43 pathology. medRxiv [Preprint]. 2023 Nov 20:2023.11.19.23298314. doi: 10.1101/2023.11.19.23298314. PMID: 38045300; PMCID: PMC10690340.

Winder Z, Sudduth TL, Anderson S, Patel E, Neltner J, Martin BJ, Snyder KE, Abner EL, Jicha GA, Nelson PT, Wilcock DM. Examining the association between blood-based biomarkers and human post mortem neuropathology in the University of Kentucky Alzheimer's Disease Research Center autopsy cohort. Alzheimers Dement. 2023 Jan;19(1):67-78. doi: 10.1002/alz.12639. Epub 2022 Mar 10. PMID: 35266629; PMCID: PMC9463400.

Bauer CE, Zachariou V, Sudduth TL, Van Eldik LJ, Jicha GA, Nelson PT, Wilcock DM, Gold BT. Plasma TDP-43 levels are associated with neuroimaging measures of brain structure in limbic regions. Alzheimers Dement (Amst). 2023 May 31;15(2):e12437. doi: 10.1002/dad2.12437. PMID: 37266411; PMCID: PMC10230689.

Afroz T, Chevalier E, Audrain M, Dumayne C, Ziehm T, Moser R, Egesipe AL, Mottier L, Ratnam M, Neumann M, Havas D, Ollier R, Piorkowska K, Chauhan M, Silva AB, Thapa S, Stöhr J, Bavdek A, Eligert V, Adolfsson O, Nelson PT, Porta S, Lee VM, Pfeifer A, Kosco-Vilbois M, Seredenina T. Immunotherapy targeting the C-terminal domain of TDP-43 decreases neuropathology and confers neuroprotection in mouse models of ALS/FTD. Neurobiol Dis. 2023 Apr;179:106050. doi: 10.1016/j.nbd.2023.106050. Epub 2023 Feb 20. PMID: 36809847.

Shahidehpour RK, Nelson AS, Sanders LG, Embry CR, Nelson PT, Bachstetter AD. The localization of molecularly distinct microglia populations to Alzheimer's disease pathologies using QUIVER. Acta Neuropathol Commun. 2023 Mar 18;11(1):45. doi: 10.1186/s40478-023-01541-w. PMID: 36934255; PMCID: PMC10024857.

Sziraki A, Zhong Y, Neltner AM, Niedowicz DM, Rogers CB, Wilcock DM, Nehra G, Neltner JH, Smith RR, Hartz AM, Cao J, Nelson PT. A high-throughput single-cell RNA expression profiling method identifies human pericyte markers. Neuropathol Appl Neurobiol. 2023 Dec;49(6):e12942. doi: 10.1111/nan.12942. PMID: 37812061; PMCID: PMC10842535.

Grothe MJ, Moscoso A, Silva-Rodríguez J, Lange C, Nho K, Saykin AJ, Nelson PT, Schöll M, Buchert R, Teipel S; Alzheimer's Disease Neuroimaging Initiative. Differential diagnosis of amnestic dementia patients based on an FDG-PET signature of autopsy-confirmed LATE-NC. Alzheimers Dement. 2023 Apr;19(4):1234-1244. doi: 10.1002/alz.12763. Epub 2022 Aug 15. PMID: 35971593; PMCID: PMC9929029.

Nelson PT, Jicha GA. Surprising Synergy Between Cerebrovascular and Lewy Body Disease in Parkinsonism. Neurology. 2023 Aug 15;101(7):290-292. doi: 10.1212/WNL.0000000000207572. Epub 2023 Jun 21. PMID: 37344229.

Verma N, Velmurugan GV, Winford E, Coburn H, Kotiya D, Leibold N, Radulescu L, Despa S, Chen KC, Van Eldik LJ, Nelson PT, Wilcock DM, Jicha GA, Stowe AM, Goldstein LB, Powel DK, Walton JH, Navedo MF, Nystoriak MA, Murray AJ, Biessels GJ, Troakes C, Zetterberg H, Hardy J, Lashley T, Despa F. Aβ efflux impairment and inflammation linked to cerebrovascular accumulation of amyloid-forming amylin secreted from pancreas. Commun Biol. 2023 Jan 3;6(1):2. doi: 10.1038/s42003-022-04398-2. PMID: 36596993; PMCID: PMC9810597.

Maioli H, Mittenzwei R, Shofer JB, Scherpelz KP, Marshall D, Nolan AL, Nelson PT, Keene CD, Latimer CS. Performance of a condensed protocol to assess limbic-predominant age-related TDP-43 encephalopathy neuropathologic change. J Neuropathol Exp Neurol. 2023 Jun 20;82(7):611-619. doi: 10.1093/jnen/nlad035. PMID: 37195467; PMCID: PMC10280345.

Sompol P, Gollihue JL, Weiss BE, Lin RL, Case SL, Kraner SD, Weekman EM, Gant JC, Rogers CB, Niedowicz DM, Sudduth TL, Powell DK, Lin AL, Nelson PT, Thibault O, Wilcock DM, Norris CM. Targeting Astrocyte Signaling Alleviates Cerebrovascular and Synaptic Function Deficits in a Diet-Based Mouse Model of Small Cerebral Vessel Disease. J Neurosci. 2023 Mar 8;43(10):1797-1813. doi: 10.1523/JNEUROSCI.1333-22.2023. Epub 2023 Feb 6. PMID: 36746627; PMCID: PMC10010459.

Section 3

Heberle BA, Brandon JA, Page ML, Nations KA, Dikobe KI, White BJ, Gordon LA, Fox GA, Wadsworth ME, Doyle PH, Williams BA, Fox EJ, Shantaraman A, Ryten M, Goodwin S, Ghiban E, Wappel R, Mavruk-Eskipehlivan S, Miller JB, Seyfried NT, Nelson PT, Fryer JD, Ebbert MTW. Using deep long-read RNAseq in Alzheimer's disease brain to assess medical relevance of RNA isoform diversity. bioRxiv [Preprint]. 2023 Dec 11:2023.08.06.552162. doi: 10.1101/2023.08.06.552162. PMID: 37609156; PMCID: PMC10441303.

Scalco R, Hamsafar Y, White CL, Schneider JA, Reichard RR, Prokop S, Perrin RJ, Nelson PT, Mooney S, Lieberman AP, Kukull WA, Kofler J, Keene CD, Kapasi A, Irwin DJ, Gutman DA, Flanagan ME, Crary JF, Chan KC, Murray ME, Dugger BN. The status of digital pathology and associated infrastructure within Alzheimer's Disease Centers. J Neuropathol Exp Neurol. 2023 Feb 21;82(3):202-211. doi: 10.1093/jnen/nlac127. PMID: 36692179; PMCID: PMC9941826.

Nelson PT, Jicha GA. Early Hippocampal Atrophy Is an Important Signal for Clinicians but Not Necessarily a Harbinger of Alzheimer Disease. Neurology. 2023 Dec 12;101(24):1087-1088. doi: 10.1212/WNL.0000000000208071. Epub 2023 Nov 8. PMID: 37968129.

Min Y, Wang X, İş Ö, Patel TA, Gao J, Reddy JS, Quicksall ZS, Nguyen T, Lin S, Tutor-New FQ, Chalk JL, Mitchell AO, Crook JE, Nelson PT, Van Eldik LJ, Golde TE, Carrasquillo MM, Dickson DW, Zhang K, Allen M, Ertekin-Taner N. Cross species systems biology discovers glial DDR2, STOM, and KANK2 as therapeutic targets in progressive supranuclear palsy. Nat Commun. 2023 Nov 2;14(1):6801. doi: 10.1038/s41467-023-42626-3. PMID: 37919278; PMCID: PMC10622416.

Niedowicz DM, Katsumata Y, Nelson PT. In severe ADNC, hippocampi with comorbid LATE-NC and hippocampal sclerosis have substantially more astrocytosis than those with LATE-NC or hippocampal sclerosis alone. J Neuropathol Exp Neurol. 2023 Nov 20;82(12):987-994. doi: 10.1093/jnen/nlad085. PMID: 37935530; PMCID: PMC10658353.

Sziraki A, Lu Z, Lee J, Banyai G, Anderson S, Abdulraouf A, Metzner E, Liao A, Banfelder J, Epstein A, Schaefer C, Xu Z, Zhang Z, Gan L, Nelson PT, Zhou W, Cao J. A global view of aging and Alzheimer's pathogenesis-associated cell population dynamics and molecular signatures in human and mouse brains. Nat Genet. 2023 Dec;55(12):2104-2116. doi: 10.1038/s41588-023-01572-y. Epub 2023 Nov 30. PMID: 38036784; PMCID: PMC10703679.

Arizaca Maquera KA, Welden JR, Margvelani G, Miranda Sardón SC, Hart S, Robil N, Hernandez AG, de la Grange P, Nelson PT, Stamm S. Alzheimer's disease pathogenetic progression is associated with changes in regulated retained introns and editing of circular RNAs. Front Mol Neurosci. 2023 May 5;16:1141079. doi: 10.3389/fnmol.2023.1141079. PMID: 37266374; PMCID: PMC10231643.

Di J, Nelson RS, Jicha GA, Moga DC, Barber JM, Cykowski MD, Fardo DW, Abner EL, Nelson PT. Urinary Incontinence in a Community-Based Autopsy Cohort Is Associated with Limbic Predominant Age-Related TDP-43 Encephalopathy Neuropathologic Changes. J Alzheimers Dis. 2023;94(1):333-346. doi: 10.3233/JAD-230425. PMID: 37248909; PMCID: PMC10618953.

Niedowicz DM, Wang WX, Price DA, Xie K, Patel E, Nelson PT. Impact of thyroid hormone perturbations in adult mice: brain weight and blood vessel changes, gene expression variation, and neurobehavioral outcomes. Neurobiol Aging. 2023 Aug;128:74-84. doi: 10.1016/j.neurobiolaging.2023.04.012. Epub 2023 Apr 29. PMID: 37229849; PMCID: PMC10247485.

Guney E, Lucas CG, Singh K, Pekmezci M, Fernandez-Pol S, Mirchia K, Toland A, Vogel H, Bannykh S, Schafernak KT, Alexandrescu S, Mobley BC, Powell S, Davidson CJ, Neltner J, Boué DR, Hattab E, Ferris SP, Ohgami RS, Rubenstein JL, Bollen AW, Tihan T, Perry A, Solomon DA, Wen KW. Molecular profiling identifies at least 3 distinct types of posttransplant lymphoproliferative disorder involving the CNS. Blood Adv. 2023 Jul 11;7(13):3307-3311. doi: 10.1182/bloodadvances.2022009521. PMID: 36897259; PMCID: PMC10336256.

Ene A, Di J, Neltner JH, Pittman T, Arnold SM, Kolesar JM, Villano JL, Bachert SE, Allison DB. Case report: A unique presentation of a high-grade neuroepithelial tumor with EWSR1::PATZ1 fusion with diagnostic, molecular, and therapeutic insights. Front Oncol. 2023 Jan 31;13:1094274. doi: 10.3389/fonc.2023.1094274. PMID: 36816978; PMCID: PMC9928596.

Section 4

Curry LD, Munker R, Li N, Yan D, Pryor P, Nozad S, Keller P, Monohan GP, Iragavarapu C, Krem MM. Performance status, comorbidities, and cycles of methotrexate exert the greatest influence on outcomes of primary and secondary CNS lymphomas: the Lexington experience. Ann Hematol. 2023 Jan;102(1):141-154. doi: 10.1007/s00277-022-05018-z. Epub 2022 Nov 11. PMID: 36367559.

Ballout JA, Arshia A, Palm DS, Reda HK, London TE, O'Connor W, Gupta VA. Multimodal Imaging and Management of a Metastatic Cardiac Intimal Sarcoma. CASE (Phila). 2023 Mar 31;7(5):163-167. doi: 10.1016/ PMID: 37325462; PMCID: PMC10264199.

Kunos CA, Fabian D, Piecoro DW, Napier D, Miller RW, Ueland FR. Human epidermal growth factor receptor 2 expression in women with uterine cervix adenocarcinoma from Appalachian Kentucky. Front Oncol. 2023 Jan 24;13:948348. doi: 10.3389/fonc.2023.948348. PMID: 36761943; PMCID: PMC9902924.

McDonald HG, Harper MM, Hill K, Gao A, Solomon AL, Bailey CJ, Lin M, Barry-Hundeyin M, Cavnar MJ, Mardini SH, Pandalai PJ, Patel RA, Kolesar JM, Rueckert JA, Hookey L, Ropeleski M, Merchant SJ, Kim J, Gao M. Creation of EGD-Derived Gastric Cancer Organoids to Predict Treatment Responses. Cancers (Basel). 2023 Jun 2;15(11):3036. doi: 10.3390/cancers15113036. PMID: 37296998; PMCID: PMC10252567.

Zelows MM, Cady C, Dharanipragada N, Mead AE, Kipp ZA, Bates EA, Varadharajan V, Banerjee R, Park SH, Shelman NR, Clarke HA, Hawkinson TR, Medina T, Sun RC, Lydic TA, Hinds TD Jr, Brown JM, Softic S, Graf GA, Helsley RN. Loss of carnitine palmitoyltransferase 1a reduces docosahexaenoic acid-containing phospholipids and drives sexually dimorphic liver disease in mice. Mol Metab. 2023 Dec;78:101815. doi: 10.1016/j.molmet.2023.101815. Epub 2023 Oct 4. PMID: 37797918; PMCID: PMC10568566.

Prajapati P, Wang WX, Pesina SA, Geleta U, Springer JE. Sex-Specific Alterations in Inflammatory MicroRNAs in Mouse Brain and Bone Marrow CD11b+ Cells Following Traumatic Brain Injury. Cell Mol Neurobiol. 2023 Jan;43(1):423-429. doi: 10.1007/s10571-021-01164-6. Epub 2021 Nov 10. PMID: 34761332.

Luo X, Maciaszek JL, Thompson BA, Leong HS, Dixon K, Sousa S, Anderson M, Roberts ME, Lee K, Spurdle AB, Mensenkamp AR, Brannan T, Pardo C, Zhang L, Pesaran T, Wei S, Fasaye GA, Kesserwan C, Shirts BH, Davis JL, Oliveira C, Plon SE, Schrader KA, Karam R; ClinGen CDH1 Variant Curation Expert Panel. Optimising clinical care through CDH1-specific germline variant curation: improvement of clinical assertions and updated curation guidelines. J Med Genet. 2023 Jun;60(6):568-575. doi: 10.1136/jmg-2022-108807. Epub 2022 Dec 7. PMID: 36600593; PMCID: PMC10202836.

Di J, Yenwongfai L, Rieger HT, Zhang S, Wei S. Familial 4p Interstitial Deletion Provides New Insights and Candidate Genes Underlying This Rare Condition. Genes (Basel). 2023 Mar 3;14(3):635. doi: 10.3390/genes14030635. PMID: 36980907; PMCID: PMC10048360.

Zhang Z, Chen X, Zhang W, Liu J, Xie Y, Zhang S, Stromberg AJ, Watt DS, Liu X, Wang C, Liu C. Genomic screening methodology not requiring barcoding: Single nucleotide polymorphism-based, mixed-cell screening (SMICS). Genomics. 2023 Sep;115(5):110666. doi: 10.1016/j.ygeno.2023.110666. Epub 2023 Jun 12. PMID: 37315874; PMCID: PMC10551848.

2022 Publications

Section 1

Zhang Z, Cheng L, Li J, Qiao Q, Karki A, Allison DB, Shaker N, Li K, Utturkar SM, Atallah Lanman NM, Rao X, Rychahou P, He D, Konieczny SF, Wang C, Shao Q, Evers BM, Liu X. Targeting Plk1 Sensitizes Pancreatic Cancer to Immune Checkpoint Therapy. Cancer Res. 2022 Oct 4;82(19):3532-3548. doi: 10.1158/0008-5472.CAN-22-0018. PMID: 35950917; PMCID: PMC9532376.

Jacob A, Raj R, Allison DB, Soares HP, Chauhan A. An Update on the Management of Mixed Neuroendocrine-Non-neuroendocrine Neoplasms (MiNEN). Curr Treat Options Oncol. 2022 May;23(5):721-735. doi: 10.1007/s11864-022-00968-y. Epub 2022 Mar 26. PMID: 35347561.

Allison DB, Zhang ML, Vohra P, VandenBussche CJ. The Diagnostic Dilemma of Urothelial Tissue Fragments in Urinary Tract Cytology Specimens. Diagnostics (Basel). 2022 Apr 8;12(4):931. doi: 10.3390/diagnostics12040931. PMID: 35453979; PMCID: PMC9025489.

Allison DB, Kates M, VandenBussche CJ. Indeterminate atypia in urinary tract cytology: Does it really matter? Diagn Cytopathol. 2022 Apr;50(4):176-183. doi: 10.1002/dc.24912. Epub 2021 Dec 6. PMID: 34870896.

Harbin LM, Gallion HH, Allison DB, Kolesar JM. Next Generation Sequencing and Molecular Biomarkers in Ovarian Cancer-An Opportunity for Targeted Therapy. Diagnostics (Basel). 2022 Mar 29;12(4):842. doi: 10.3390/diagnostics12040842. PMID: 35453890; PMCID: PMC9030726.

Kong Y, Allison DB, Zhang Q, He D, Li Y, Mao F, Li C, Li Z, Zhang Y, Wang J, Wang C, Brainson CF, Liu X. The kinase PLK1 promotes the development of Kras/Tp53-mutant lung adenocarcinoma through transcriptional activation of the receptor RET. Sci Signal. 2022 Oct 4;15(754):eabj4009. doi: 10.1126/scisignal.abj4009. Epub 2022 Oct 4. PMID: 36194647; PMCID: PMC9737055.

Priyadarshini S, Allison DB, Chauhan A. Comprehensive Assessment of Somatostatin Receptors in Various Neoplasms: A Systematic Review. Pharmaceutics. 2022 Jul 1;14(7):1394. doi: 10.3390/pharmaceutics14071394. PMID: 35890290; PMCID: PMC9325105.

Hawkinson TR, Clarke HA, Young LEA, Conroy LR, Markussen KH, Kerch KM, Johnson LA, Nelson PT, Wang C, Allison DB, Gentry MS, Sun RC. In situ spatial glycomic imaging of mouse and human Alzheimer's disease brains. Alzheimers Dement. 2022 Oct;18(10):1721-1735. doi: 10.1002/alz.12523. Epub 2021 Dec 15. PMID: 34908231; PMCID: PMC9198106.

Jassim TK, Ferreira JE, Murphy MB, Piecoro DW, Allison DB. The use of diagnostic patterns for interventional cytopathology during rapid on-site evaluation and final classification. Semin Diagn Pathol. 2022 Nov;39(6):394-404. doi: 10.1053/j.semdp.2022.06.014. Epub 2022 Jun 14. PMID: 35725678.

Conroy LR, Chang JE, Sun Q, Clarke HA, Buoncristiani MD, Young LEA, McDonald RJ, Liu J, Gentry MS, Allison DB, Sun RC. High-dimensionality reduction clustering of complex carbohydrates to study lung cancer metabolic heterogeneity. Adv Cancer Res. 2022;154:227-251. doi: 10.1016/bs.acr.2022.02.005. Epub 2022 Mar 18. PMID: 35459471; PMCID: PMC9273336.

Maleki Z, Saoud C, Viswanathan K, Kilic I, Tommola E, Griffin DT, Heider A, Petrone G, Jo VY, Centeno BA, Saieg M, Mikou P, Fadda G, Ali SZ, Kholová I, Wojcik EM, Barkan GA, Eisele DW, Bellevicine C, Vigliar E, Wiles AB, Al-Ibraheemi A, Allison DB, Dixon GR, Chandra A, Walsh JM, Baloch ZW, Faquin WC, Krane JF, Rossi ED, Pantanowitz L, Troncone G, Callegari FM, Klijanienko J. Application of the Milan System for Reporting Salivary Gland Cytopathology in pediatric patients: An international, multi-institutional study. Cancer Cytopathol. 2022 May;130(5):370-380. doi: 10.1002/cncy.22556. Epub 2022 Jan 26. PMID: 35081269.

Hang JF, Lee JJL, Nga ME, Higuchi K, Hirata Y, Wu HH, Allison DB, Gilbert JD, Lin O, Saieg M, de Arruda AF, Chen YA, Huang EC, Manucha V. Multi-institutional validation of a modified scheme for subcategorizing salivary gland neoplasm of uncertain malignant potential (SUMP). Cancer Cytopathol. 2022 Jul;130(7):511-522. doi: 10.1002/cncy.22593. Epub 2022 May 30. PMID: 35637575.

Gunawardane SP, Kramer ME, Bearden JM, Resar JR, Lawton JS, Allison DB, Becker RM, Zhang WW, Premaratne S. Chronic migraine with aura as a neurologic manifestation of an atrial myxoma - A case report. Int J Surg Case Rep. 2022 Mar;92:106894. doi: 10.1016/j.ijscr.2022.106894. Epub 2022 Mar 7. PMID: 35278985; PMCID: PMC8914198.

Jones VM, Wangsiricharoen S, Cornea V, Bocklage TJ, Ali SZ, Allison DB. Cytopathological characteristics of solitary fibrous tumour involving the pancreas by fine needle aspiration: Making an accurate preoperative diagnosis in an uncommon location. Cytopathology. 2022 Mar;33(2):222-229. doi: 10.1111/cyt.13061. Epub 2021 Oct 3. PMID: 34551176.

Allison DB, Rueckert J, Cornea V, Lee CY, Dueber J, Bocklage T. Thyroid Carcinoma with NSD3::NUTM1 Fusion: a Case with Thyrocyte Differentiation and Colloid Production. Endocr Pathol. 2022 Jun;33(2):315-326. doi: 10.1007/s12022-021-09700-2. Epub 2022 Jan 8. PMID: 34997561; PMCID: PMC9135820.

Miller RW, Hutchcraft ML, Weiss HL, Wu J, Wang C, Liu J, Jayswal R, Buchanan M, Anderson A, Allison DB, El Khouli RH, Patel RA, Villano JL, Arnold SM, Kolesar JM. Molecular Tumor Board-Assisted Care in an Advanced Cancer Population: Results of a Phase II Clinical Trial. JCO Precis Oncol. 2022 Aug;6:e2100524. doi: 10.1200/PO.21.00524. PMID: 36103643; PMCID: PMC9489195.

Section 2

Young LEA, Conroy LR, Clarke HA, Hawkinson TR, Bolton KE, Sanders WC, Chang JE, Webb MB, Alilain WJ, Vander Kooi CW, Drake RR, Andres DA, Badgett TC, Wagner LM, Allison DB, Sun RC, Gentry MS. In situ mass spectrometry imaging reveals heterogeneous glycogen stores in human normal and cancerous tissues. EMBO Mol Med. 2022 Nov 8;14(11):e16029. doi: 10.15252/emmm.202216029. Epub 2022 Sep 5. PMID: 36059248; PMCID: PMC9641418.

Al-Qurayshi Z, Sullivan CB, Allison DB, Buchakjian MR. Presentation and outcomes of patients with clinically T1-2, N0 parotid mucoepidermoid carcinoma: The roles of elective neck dissection and adjuvant radiotherapy. Head Neck. 2022 Oct;44(10):2151-2161. doi: 10.1002/hed.27128. Epub 2022 Jun 22. PMID: 35731030; PMCID: PMC9544346.

Wahlstedt ER, Allison DB, Bell JR. Adult granulosa cell tumour of the testis: an uncommon tumour. BMJ Case Rep. 2022 Dec 26;15(12):e253063. doi: 10.1136/bcr-2022-253063. PMID: 36572453; PMCID: PMC9806054.

Smith T, Holm RH, Yeager R, Moore JB 4th, Rouchka EC, Sokoloski KJ, Elliott EM, Talley D, Arora V, Moyer S, Bhatnagar A. Combining Community Wastewater Genomic Surveillance with State Clinical Surveillance: A Framework for SARS-CoV-2 Public Health Practice. Food Environ Virol. 2022 Dec;14(4):410-416. doi: 10.1007/s12560-022-09531-2. Epub 2022 Aug 18. PMID: 35982363; PMCID: PMC9387882.

Shaheen MF, Tse JY, Sokol ES, Masterson M, Bansal P, Rabinowitz I, Tarleton CA, Dobroff AS, Smith TL, Bocklage TJ, Mannakee BK, Gutenkunst RN, Bischoff J, Ness SA, Riedlinger GM, Groisberg R, Pasqualini R, Ganesan S, Arap W. Genomic landscape of lymphatic malformations: a case series and response to the PI3Kα inhibitor alpelisib in an N-of-1 clinical trial. Elife. 2022 Jul 5;11:e74510. doi: 10.7554/eLife.74510. PMID: 35787784; PMCID: PMC9255965.

Jones VM, Wangsiricharoen S, Cornea V, Bocklage TJ, Ali SZ, Allison DB. Cytopathological characteristics of solitary fibrous tumour involving the pancreas by fine needle aspiration: Making an accurate preoperative diagnosis in an uncommon location. Cytopathology. 2022 Mar;33(2):222-229. doi: 10.1111/cyt.13061. Epub 2021 Oct 3. PMID: 34551176.

Riggs MJ, Huang B, Chen Q, Bocklage T, Schuh MR, Poi M, Villano JL, Cavnar MJ, Arnold SM, Miller RW, Ueland FR, Kolesar JM. Factors Predicting Participation in the Prospective Genomic Sequencing Study, Total Cancer Care (TCC), in Kentucky. J Rural Health. 2022 Jan;38(1):5-13. doi: 10.1111/jrh.12492. Epub 2020 Jul 6. PMID: 32633045; PMCID: PMC8111685.

Gedaly R, Cornea V, Turcios L, Edmisson JS, Harris DD, Watt DS, Chapelin F, Khurana A, Mei X, Liu C, Taylor I, Gonzalez-Valdivieso J, Mitchel H, Ruffing A, Chishti A, Orozco G, Zwischenberger J, Evers BM, Marti F. Anti-neoplastic sulfonamides alter the metabolic homeostasis and disrupt the suppressor activity of regulatory T cells. Sci Rep. 2022 Nov 9;12(1):19112. doi: 10.1038/s41598-022-23601-2. PMID: 36352020; PMCID: PMC9646802.

Josephson L, Cornea V, Stoner BJ, El-Dalati S. Cryoglobulinemic vasculitis in two patients with infective endocarditis: a case series. Ther Adv Infect Dis. 2022 Aug 3;9:20499361221113464. doi: 10.1177/20499361221113464. PMID: 35937927; PMCID: PMC9354131.

Ibrahim W, McCoy MH. A 62-Year-Old Male Presenting with Hemarthrosis and Isolated Prolongation of aPTT. Clin Chem. 2022 Jul 3;68(7):992-993. doi: 10.1093/clinchem/hvac057. PMID: 36103324.

Shaw BC, Maglinger GB, Ujas T, Rupareliya C, Fraser JF, Grupke S, Kesler M, Gelderblom M, Pennypacker KR, Turchan-Cholewo J, Stowe AM. Isolation and identification of leukocyte populations in intracranial blood collected during mechanical thrombectomy. J Cereb Blood Flow Metab. 2022 Feb;42(2):280-291. doi: 10.1177/0271678X211028496. Epub 2021 Jul 11. PMID: 34250820; PMCID: PMC8795221.

Drury J, Rychahou PG, Kelson CO, Geisen ME, Wu Y, He D, Wang C, Lee EY, Evers BM, Zaytseva YY. Upregulation of CD36, a Fatty Acid Translocase, Promotes Colorectal Cancer Metastasis by Increasing MMP28 and Decreasing E-Cadherin Expression. Cancers (Basel). 2022 Jan 5;14(1):252. doi: 10.3390/cancers14010252. PMID: 35008415; PMCID: PMC8750155.

Jiang J, Turpin C, Qiu GS, Xu M, Lee E, Hinds TD Jr, Peterson ML, Spear BT. Zinc fingers and homeoboxes 2 is required for diethylnitrosamine-induced liver tumor formation in C57BL/6 mice. Hepatol Commun. 2022 Dec;6(12):3550-3562. doi: 10.1002/hep4.2106. Epub 2022 Oct 4. PMID: 36194180; PMCID: PMC9701486.

Lennerz JK, Pantanowitz L, Amin MB, Eltoum IE, Hameed MR, Kalof AN, Khanafshar E, Kunju LP, Lazenby AJ, Montone KT, Otis CN, Reid MD, Staats PN, Whitney-Miller CL, Abendroth CS, Aron M, Birdsong GG, Bleiweiss IJ, Bronner MP, Chapman J, Cipriani NA, de la Roza G, Esposito MJ, Fadare O, Ferrer K, Fletcher CD, Frishberg DP, Garcia FU, Geldenhuys L, Gill RM, Gui D, Halat S, Hameed O, Hornick JL, Huber AR, Jain D, Jhala N, Jorda M, Jorns JM, Kaplan J, Khalifa MA, Khan A, Kim GE, Lee EY, LiVolsi VA, Longacre T, Magi-Galluzzi C, McCall SJ, McPhaul L, Mehta V, Merzianu M, Miller SB, Molberg KH, Moreira AL, Naini BV, Nosé V, O'Toole K, Picken M, Prieto VG, Pullman JM, Quick CM, Reynolds JP, Rosenberg AE, Schnitt SJ, Schwartz MR, Sekosan M, Smith MT, Sohani A, Stowman A, Vanguri VK, Wang B, Watts JC, Wei S, Whitney K, Younes M, Zee S, Bracamonte ER. Ensuring remote diagnostics for pathologists: an open letter to the US Congress. Nat Med. 2022 Dec;28(12):2453-2455. doi: 10.1038/s41591-022-02040-6. PMID: 36266514.

Section 3

Teerlink CC, Miller JB, Vance EL, Staley LA, Stevens J, Tavana JP, Cloward ME, Page ML, Dayton L; Alzheimer's Disease Genetics Consortium; Cannon-Albright LA, Kauwe JSK. Analysis of high-risk pedigrees identifies 11 candidate variants for Alzheimer's disease. Alzheimers Dement. 2022 Feb;18(2):307-317. doi: 10.1002/alz.12397. Epub 2021 Jun 20. PMID: 34151536; PMCID: PMC9291865.

Miller JB, Meurs TE, Hodgman MW, Song B, Miller KN, Ebbert MTW, Kauwe JSK, Ridge PG. The Ramp Atlas: facilitating tissue and cell-specific ramp sequence analyses through an intuitive web interface. NAR Genom Bioinform. 2022 May 30;4(2):lqac039. doi: 10.1093/nargab/lqac039. PMID: 35664804; PMCID: PMC9155233.

Ward KM, Pickett BD, Ebbert MTW, Kauwe JSK, Miller JB. Web-Based Protein Interactions Calculator Identifies Likely Proteome Coevolution with Alzheimer's Disease-Associated Proteins. Genes (Basel). 2022 Jul 27;13(8):1346. doi: 10.3390/genes13081346. PMID: 36011253; PMCID: PMC9407263.

Welden JR, Margvelani G, Arizaca Maquera KA, Gudlavalleti B, Miranda Sardón SC, Campos AR, Robil N, Lee DC, Hernandez AG, Wang WX, Di J, de la Grange P, Nelson PT, Stamm S. RNA editing of microtubule-associated protein tau circular RNAs promotes their translation and tau tangle formation. Nucleic Acids Res. 2022 Dec 9;50(22):12979-12996. doi: 10.1093/nar/gkac1129. PMID: 36533443; PMCID: PMC9825173.

Shade LM, Katsumata Y, Hohman TJ, Nho K, Saykin AJ, Mukherjee S, Boehme KL, Kauwe JS, Farrer LA, Schellenberg GD, Haines JL, Mayeux RP, Schneider JA, Nelson PT, Fardo DW. Genome-wide association study of brain arteriolosclerosis. J Cereb Blood Flow Metab. 2022 Aug;42(8):1437-1450. doi: 10.1177/0271678X211066299. Epub 2022 Feb 14. PMID: 35156446; PMCID: PMC9274864.

Farrell K, Kim S, Han N, Iida MA, Gonzalez EM, Otero-Garcia M, Walker JM, Richardson TE, Renton AE, Andrews SJ, Fulton-Howard B, Humphrey J, Vialle RA, Bowles KR, de Paiva Lopes K, Whitney K, Dangoor DK, Walsh H, Marcora E, Hefti MM, Casella A, Sissoko CT, Kapoor M, Novikova G, Udine E, Wong G, Tang W, Bhangale T, Hunkapiller J, Ayalon G, Graham RR, Cherry JD, Cortes EP, Borukov VY, McKee AC, Stein TD, Vonsattel JP, Teich AF, Gearing M, Glass J, Troncoso JC, Frosch MP, Hyman BT, Dickson DW, Murray ME, Attems J, Flanagan ME, Mao Q, Mesulam MM, Weintraub S, Woltjer RL, Pham T, Kofler J, Schneider JA, Yu L, Purohit DP, Haroutunian V, Hof PR, Gandy S, Sano M, Beach TG, Poon W, Kawas CH, Corrada MM, Rissman RA, Metcalf J, Shuldberg S, Salehi B, Nelson PT, Trojanowski JQ, Lee EB, Wolk DA, McMillan CT, Keene CD, Latimer CS, Montine TJ, Kovacs GG, Lutz MI, Fischer P, Perrin RJ, Cairns NJ, Franklin EE, Cohen HT, Raj T, Cobos I, Frost B, Goate A, White Iii CL, Crary JF. Genome-wide association study and functional validation implicates JADE1 in tauopathy. Acta Neuropathol. 2022 Jan;143(1):33-53. doi: 10.1007/s00401-021-02379-z. Epub 2021 Nov 1. PMID: 34719765; PMCID: PMC8786260.

Nelson PT, Brayne C, Flanagan ME, Abner EL, Agrawal S, Attems J, Castellani RJ, Corrada MM, Cykowski MD, Di J, Dickson DW, Dugger BN, Ervin JF, Fleming J, Graff-Radford J, Grinberg LT, Hokkanen SRK, Hunter S, Kapasi A, Kawas CH, Keage HAD, Keene CD, Kero M, Knopman DS, Kouri N, Kovacs GG, Labuzan SA, Larson EB, Latimer CS, Leite REP, Matchett BJ, Matthews FE, Merrick R, Montine TJ, Murray ME, Myllykangas L, Nag S, Nelson RS, Neltner JH, Nguyen AT, Petersen RC, Polvikoski T, Reichard RR, Rodriguez RD, Suemoto CK, Wang SJ, Wharton SB, White L, Schneider JA. Frequency of LATE neuropathologic change across the spectrum of Alzheimer's disease neuropathology: combined data from 13 community-based or population-based autopsy cohorts. Acta Neuropathol. 2022 Jul;144(1):27-44. doi: 10.1007/s00401-022-02444-1. Epub 2022 Jun 13. PMID: 35697880; PMCID: PMC9552938.

Wu X, Peng C, Nelson PT, Cheng Q. Machine Learning Approach Predicts Probability of Time to Stage-Specific Conversion of Alzheimer's Disease. J Alzheimers Dis. 2022;90(2):891-903. doi: 10.3233/JAD-220590. PMID: 36189595; PMCID: PMC9840816.

Weekman EM, Winder Z, Rogers CB, Abner EL, Sudduth TL, Patel E, Dugan AJ, Fister SX, Wasek B, Nelson PT, Jicha GA, Bottiglieri T, Fardo DW, Wilcock DM. Genetic expression changes and pathologic findings associated with hyperhomocysteinemia in human autopsy brain tissue. Alzheimers Dement (N Y). 2022 Dec 8;8(1):e12368. doi: 10.1002/trc2.12368. PMID: 36514441; PMCID: PMC9732462.

Srinivasan S, Gal J, Bachstetter A, Nelson PT. Alpha adaptins show isoform-specific association with neurofibrillary tangles in Alzheimer's disease. Neuropathol Appl Neurobiol. 2022 Feb;48(2):e12776. doi: 10.1111/nan.12776. Epub 2021 Dec 7. PMID: 34820873; PMCID: PMC8810620.

Section 4

Gauthreaux KM, Teylan MA, Katsumata Y, Mock C, Culhane JE, Chen YC, Chan KCG, Fardo DW, Dugan AJ, Cykowski MD, Jicha GA, Kukull WA, Nelson PT. Limbic-Predominant Age-Related TDP-43 Encephalopathy: Medical and Pathologic Factors Associated With Comorbid Hippocampal Sclerosis. Neurology. 2022 Apr 5;98(14):e1422-e1433. doi: 10.1212/WNL.0000000000200001. Epub 2022 Feb 4. PMID: 35121671; PMCID: PMC8992604.

Dugan AJ, Nelson PT, Katsumata Y, Shade LMP, Teylan MA, Boehme KL, Mukherjee S, Kauwe JSK, Hohman TJ, Schneider JA, Fardo DW; Alzheimer's Disease Genetics Consortium. Association between WWOX/MAF variants and dementia-related neuropathologic endophenotypes. Neurobiol Aging. 2022 Mar;111:95-106. doi: 10.1016/j.neurobiolaging.2021.10.011. Epub 2021 Oct 29. PMID: 34852950; PMCID: PMC8761217.

Gal J, Katsumata Y, Zhu H, Srinivasan S, Chen J, Johnson LA, Wang WX, Golden LR, Wilcock DM, Jicha GA, Cykowski MD, Nelson PT. Apolipoprotein E Proteinopathy Is a Major Dementia-Associated Pathologic Biomarker in Individuals with or without the APOE Epsilon 4 Allele. Am J Pathol. 2022 Mar;192(3):564-578. doi: 10.1016/j.ajpath.2021.11.013. Epub 2021 Dec 24. PMID: 34954207; PMCID: PMC8895423.

Rhodus EK, Barber J, Kryscio RJ, Abner EL, Bahrani AA, Lewis KES, Carey B, Nelson PT, Van Eldik LJ, Jicha GA. Frontotemporal neurofibrillary tangles and cerebrovascular lesions are associated with autism spectrum behaviors in late-life dementia. J Neurol. 2022 Sep;269(9):5105-5113. doi: 10.1007/s00415-022-11167-y. Epub 2022 May 21. PMID: 35596794; PMCID: PMC9644295.

Gauthreaux K, Mock C, Teylan MA, Culhane JE, Chen YC, Chan KCG, Katsumata Y, Nelson PT, Kukull WA. Symptomatic Profile and Cognitive Performance in Autopsy-Confirmed Limbic-Predominant Age-Related TDP-43 Encephalopathy With Comorbid Alzheimer Disease. J Neuropathol Exp Neurol. 2022 Nov 16;81(12):975-987. doi: 10.1093/jnen/nlac093. PMID: 36264254; PMCID: PMC9677237.

Wang R, Chopra N, Nho K, Maloney B, Obukhov AG, Nelson PT, Counts SE, Lahiri DK. Human microRNA (miR-20b-5p) modulates Alzheimer's disease pathways and neuronal function, and a specific polymorphism close to the MIR20B gene influences Alzheimer's biomarkers. Mol Psychiatry. 2022 Feb;27(2):1256-1273. doi: 10.1038/s41380-021-01351-3. Epub 2022 Jan 27. PMID: 35087196; PMCID: PMC9054681.

Cykowski MD, Arumanayagam AS, Powell SZ, Rivera AL, Abner EL, Roman GC, Masdeu JC, Nelson PT. Patterns of amygdala region pathology in LATE-NC: subtypes that differ with regard to TDP-43 histopathology, genetic risk factors, and comorbid pathologies. Acta Neuropathol. 2022 May;143(5):531-545. doi: 10.1007/s00401-022-02416-5. Epub 2022 Apr 2. PMID: 35366087; PMCID: PMC9038848.

Wu X, Peng C, Nelson PT, Cheng Q. Deep learning algorithm reveals probabilities of stage-specific time to conversion in individuals with neurodegenerative disease LATE. Alzheimers Dement (N Y). 2022 Nov 3;8(1):e12363. doi: 10.1002/trc2.12363. PMID: 36348767; PMCID: PMC9632667.

Ionel DL, Odago FO, Ene AN, Lee JD, O'Connor WN, Goldstein LB, Pettigrew LC. Paradoxical Cerebral Air Embolism after Cardiac Ablation in Williams-Beuren Syndrome: A Clinico-Pathological Correlation. J Stroke Cerebrovasc Dis. 2022 Apr;31(4):106317. doi: 10.1016/j.jstrokecerebrovasdis.2022.106317. Epub 2022 Feb 2. PMID: 35123277.

Villacorta Cari E, Leedy N, Ribes JA, Soria J, Myint T. Risk factors of severe blastomycosis and comparison of diagnosis and outcomes between immunocompetent and immunocompromised patients. Mycoses. 2022 Feb;65(2):239-246. doi: 10.1111/myc.13409. Epub 2021 Dec 29. PMID: 34874582.

Hutchcraft ML, Zhang S, Lin N, Gottschalk GL, Keck JW, Belcher EA, Sears C, Wang C, Liu K, Dietz LE, Pickarski JC, Wei S, Cardarelli R, DiPaola RS, Kolesar JM. Real-World Evaluation of a Population Germline Genetic Screening Initiative for Family Medicine Patients. J Pers Med. 2022 Aug 8;12(8):1297. doi: 10.3390/jpm12081297. PMID: 36013246; PMCID: PMC9410316.

Wei R, Zhou Y, Li C, Rychahou P, Zhang S, Titlow WB, Bauman G, Wu Y, Liu J, Wang C, Weiss HL, Evers BM, Wang Q. Ketogenesis Attenuates KLF5-Dependent Production of CXCL12 to Overcome the Immunosuppressive Tumor Microenvironment in Colorectal Cancer. Cancer Res. 2022 Apr 15;82(8):1575-1588. doi: 10.1158/0008-5472.CAN-21-2778. PMID: 35247887; PMCID: PMC9018557.

2021 Publications

Section 1

Allison, DB. Spotlight: Rising Stars in Cytology.  Cancer Cytopathology (Online Pre-print May 12, 2021).

Allison, DB. Challenges in Recognizing Urothelial Carcinoma in situ with Plasmacytoid Features by Urinary Cytology. Cancer Cytopathology. 2021 Oct;129(10):772-773. doi:10.1002/cncy.22446. (Online Pre-print April 26, 2021).

Moore RF, Zhang XR, Allison DB, Rooper LM, Campbell AA, Eberhard CG. High-Risk Human Papillomavirus and ZEB1 in Ocular Adnexal Sebaceous Carcinoma. Journal of Cutaneous Pathology. 2021; 1-7.

Jones VM, Wangsiricharoen S, Cornea VBocklage TJ, Ali SZ, Allison DB, Jones VM, et al. Among authors: Bocklage TJ. Cytopathological characteristics of solitary fibrous tumour involving the pancreas by fine needle aspiration: Making an accurate preoperative diagnosis in an uncommon location.  Cytopathology. 2021 Sep 22. doi: 10.1111/cyt.13061. Online ahead of print. Cytopathology. 2021. PMID: 34551176.

Myint ZW, Sun RC, Hensley PJ, James AC, Wang P, Strup SE, McDonald RJ, Yan D, St. Clair WH, Allison DB. Evaluation of Glutaminase Expression in Prostate Adenocarcinoma and Correlation with Clinicopathologic Parameters. Cancers. 2021; 13(9):2157.

Stanback AE, Conroy LR, Young LEA, Markussen KH, Hawkinson TR, Clark HA, Allison DB, Sun RC. Regional N-Glycan and Lipid Analysis from Tissues Using MALDI-Mass Spectrometry Imaging. STAR Protocols. 2021;2(1):100304.

Smith AP, Dueber JCAllison DB. A Diagnostic Review of Carcinomas and Sarcomas of the Mediastinum: Making the diagnosis on fine-needle aspiration and core needle biopsy specimens. Semin Diagn Pathol. 2020;37(4):187-198.

Allison DB, Smith AP, An D, et al. Assessing the diagnostic accuracy for pleomorphic adenoma and warthin tumor by employing the Milan System for Reporting Salivary Gland Cytopathology: An international, multi-institutional study. [published online ahead of print, Aug 7, 2020]. Cancer Cytopathol. 2021;129(1):43-52.29)

Zahra M, Allison DB, Hill M, Satomi K, David E, Pantanowitz L. Application of The Milan System for Reporting Salivary Gland Cytopathology to Cystic Salivary Gland Lesions. Cancer Cytopathol.2021;129:214-25.30)

Allison DB, Wiles A, Maleki Z. Reply to Assessing the diagnostic accuracy for pleomorphic adenoma and Warthin tumor by employing the Milan System for Reporting Salivary Gland Cytopathology: An international, multi-institutional study. Cancer Cytopathol 2021;129:406-7.

Stanback AE, Conroy LR, Young LEA, Markussen KH, Hawkinson TR, Clark HA, Allison DB, Sun RC. Regional N-Glycan and Lipid Analysis from Tissues Using MALDI-Mass Spectrometry Imaging. STAR Protocols. 2021;2(1):100304.

Moore RF, Zhang XR, Allison DB, Rooper LM, Campbell AA, Eberhard CG. High-Risk Human Papillomavirus and ZEB1 in Ocular Adnexal Sebaceous Carcinoma. Journal of Cutaneous Pathology. 2021; 1– 7.

Allison DB. Challenges in Recognizing Urothelial Carcinoma in situ with Plasmacytoid Features by Urinary Cytology. Cancer Cytopathology. 2021;129:772-3.

Myint ZW, Sun RC, Hensley PJ, James AC, Wang P, Strup SE, McDonald RJ, Yan D, St. Clair WH, Allison DB. Evaluation of Glutaminase Expression in Prostate Adenocarcinoma and Correlation with Clinicopathologic Parameters. Cancers. 2021;13: 2157.

Allison DB. Spotlight: Rising Stars in Cytology. Cancer Cytopathology. 2021;129:499-500.

Conroy LR, Stanback AE, Young LEA, Clarke HA, Austin GL, Liu J, Allison DB, Sun RC. In situ analysis of N-linked Glycans as Potential Biomarkers of Clinical Course in Human Prostate Cancer. Molecular Cancer Research 2021;19:1727-38.

Wake LM, Allison DB, Ware AD, et al. Pathology Residency Program Special Expertise Tracks Meet the Needs of an Evolving Field. Academic Pathology. 2021;8.

Myint ZW, Allison DB, Ellis CS. A Case Report of Metastatic Castration-Resistant Prostate Cancer Harboring a PTEN Loss. Frontiers in Oncology. 2021;11:731002.

Section 2

Huang B, Chen Q, Allison DB, El Khouli R, Peh KH, Mobley J, et al. Molecular Tumor Board Review and Improved Overall Survival in Non–Small-Cell Lung Cancer. JCO Precision Oncology. 2021:1530-9.

Jacob A, Raj R, Allison DB, Myint ZW. Androgen Receptor Signaling in Prostate Cancer and Therapeutic Strategies. Cancers. 2021; 13(21):5417.

Hawkinson TR, Clarke HA, Young LEA, Conroy LR, Markussen KH, Kerch KM, Johnson LA, Nelson PT, Wang C, Allison DB, Gentry MS, Sun RC. In situ spatial glycomic imaging of mouse and human Alzheimer's disease brains. Alzheimer's & Dementia. 2021, Pre-print online.

Bhatt, M; JZ Porterfireld; JA Ribes, V Arora; T Myint.  Changing Demographics and Risk Factors for Cryptococcosis: A 12 Year Review at a Tertiary Care Center.  Accepted for Publication May 18, 2021 in Mycoses DOI: 10.1111/myc.13323.

Cavanaugh AM, Fortier S, Lewis P, Arora V, et al. COVID-19 Outbreak Associated with a SARS-CoV-2 R.1 Lineage Variant in a Skilled Nursing Facility After Vaccination Program-Kentucky, March 2021. MMWR Morb Mortal Wkly Rep 2021; 70:639-643. DOI:

Rowe AD, Stoway SD, Ahlman H, Arora V, Caggana M, Fornari A, Hagar A, Hall PL, Marquardt GC, Miller BJ, Nixon C, Norgan AP, Orsini JJ, Pettersen RD, Piaza AL, Schubauer NR, Smith AC, Tang H, Tavakoli NP, Wei S, Zetterstrom RH, Currier RJ, Morkrid L, Rinaldo P.  A Novel Approach to Improve Newborn Screening for Congenital Hypothyroidism by Integrating Tools.  International Journal of Neonatal Screening. 2021; 7(2):23.

Rowe AD, Stoway SD, Ahlman H, Arora V, Caggana, Fornari A, Hall PL, Marquardt GC, Miller BJ, Nixon C, Norgan AP, Orsini JJ, Pettersen RD, Piazza AL, Schubauer NR, Smith AC, Tang H, Tavakoli N, Wei S, Zetterstrom RH, Currier RJ, Morkrid L, and Rinaldo P. Enhanced performance of newborn screening for congenital hypothyroidism by integrating covariate-adjusted results of different tests into CLIR customized interpretive tools Int J Neonatal Screen 2021;7(2):23.

Fan TW, Higashi RM, Song H, Daneshmandi S, Mahan AL, Purdom MS, Bocklage TJ, Pittman TA, He D, Wang C, Lane AN, Fan TW, et al. Innate immune activation by checkpoint inhibition in human patient-derived lung cancer tissues. Among authors: Bocklage TJ. Elife. 2021 Aug 18; 10:e69578. doi: 10.7554/eLife.69578.Elife. 2021. PMID: 34406120.

Neltner JBocklage T. Levering adult learning principles into a residency core curriculum.  Cancer Cytopathol. 2021 Jul;129(7):501-505. doi:10.1002/cncy.22418. Epub 2021 Mar 19. PMID: 33739608.

Gan T, Schaberg KB, He D, Mansour A, Kapoor H, Wang C, Evers BM, Bocklage TJ.  Association Between Obesity and Histological Tumor Budding in Patients With Nonmetastatic Colon Cancer. JAMA Netw Open. 2021 Apr 1;4(4):e213897.doi:10.1001/jamanetworkopen. 2021.3897.  PMID: 33792733; PMCID:  PMC8017472.

Brainson CF, Huang B, Chen Q, McLouth LE, He C, HAE Z, Arnold SM, Zinner RG, Mullett TW, Bocklage TJ, Orren DK, Villano JL, Drubin EB. Description of a Lung Cancer Hotspot: Disparities in Lung Cancer Histology, Incidence, and Survival in Kentucky and Appalachian Kentucky. Clin Lung Cancer. 2021 Mar 26:S1525-7304(21)00061-9. doi: 10.1016/j.cllc.2021.03.007. Epub ahead of print. PMID: 33958300.

Corey B Hughes, George M Mussman, Phil Ray, Robert C Bunn, Virgilius Cornea, Kathryn M Thraikill, John L Fowlkes, luliana Popescu, Impact of an SGLT2-loss of function mutation on renal architecture, histology, and glucose homeostasis, Cell and Tissue Research, 384, pages 527-543 (2021).

Bachert SE, Baldwin LA, Dueber JCWest-Piecoro D. Ovarian Primitive Neuroectodermal Tumor: Are you central or peripheral? Int J Gynecol Pathol. 2021 Apr 12;. doi: 10.1097/PGP.0000000000000789. [Epub ahead of print] PubMed PMID: 33852507.

Gwag T, Mooli RG, Li D, Lee S, Lee EY, Wang S. Macrophage-derived thromboplastin 1 promotes obesity-associated non-alcoholic fatty liver disease.  JHEP Rep.2021 Feb:3(1): 100193.

Johnson J, Chow Z, Lee EY, Weiss HL, Evers BM, Rychahou P. Role of Akt and AMPk in triple negative breast cancer lung metastasis. Neoplasia. 23(4): 429-438, 2021.

Kim JT, Napier DL, Kim J, Li C, Lee EY, Weiss HL, Wang Q, Evers BM. Ketogenesis alleviates TNF a-induced apoptosis and inflammatory responses in intestinal cells. Free Radical Biology. 172:90-100, 2021.

Schinstock CA, Askar M, Bagnasco SM, Batal I, Bow L, Budde K, Campbell P, Carroll R, Clahsen-van Groningen MC, Cooper M, Cornell LD, Cozzi E, Dadhania D, Diekmann F, Hesselink DA, Jackson AM, Kikic Z, Lower F, Naesens M, Roelofs JJ, Sapir-Pichhadze R, Kraus ES: A 2020 Banff antibody-mediated injury working group examination of international practices for diagnosing antibody-mediated rejection in kidney transplantation- a cohort study. Transplant International 34:488, 2021.

Karanth SD, Schmitt FA, Nelson PT, Katsumata Y, Kryscio RJ, Fardo DW, Harp JP, Abner EL. Four Common Late-Life Cognitive Trajectories Patterns Associated with Replicable Underlying Neuropathologies.  J Alzheimers Dis. 2021 May 28. doi: 10.3233/JAD-210293. PMID: 34057090

Section 3

Heindl S, Ricci A, Carofiglio O, Zhou Q, Arzberger T, Lenart N, Franzmeier N, Hortobagyi T, Nelson PT, Stowe AM, Denes A, Edbauer D, Liesz A. Chronic T cell proliferation in brains after stroke could interfere with the efficacy of immunotherapies.  J Exp Med. 2021 Aug 2;218(8);e20202411.doi: 10.1084/jem.20202411. PMID: 34037669

Bachstetter AD, Garrett FG, Jicha GA, Nelson PT. Space-occupying brain lesions, trauma-related tau astrogliopathy, and ARTAG: a report of two cases and a literature review. Acta Neuropathol Commun. 2021 Mar 23;9(1):49. doi: 10.1186/s40478-021-01152-3. PMID: 33757579

Kelly SC, Nelson PT, Counts SE. Pontine Arteriolosclerosis and Locus Coeruleus Oxidative Stress Differentiate Resilience from Mild Cognitive Impairment in a Clinical Pathologic Cohort. J Neuropathol Exp Neurol. 2021 Mar 22;80(4):325-335. doi:10.1093/jnen/nlab017. PMID: 33709107

Ly H, Verma N, Sharma S, Kotiya D, Despa S, Abner EL, Nelson PT, Jicha GA, Wilcock DM, Goldstein LB, Guerreiro R, Bras J, Hanson AJ, Craft S, Murray AJ, Biessels GJ, Troakes C, Zetterberg H, Hardy J, Lashley T, Aesg, Despa F. The association of circulating amylin with B-amyloid in familial Alzheimer's disease.  Alzheimers Dement (NY). 2021 Jan 20;7(1):e12130. doi: 10.1002/trc2.12130 PMID: 33521236

Shahidehpour RK, Higdon RE, Crawford NG, Neltner JH, Ighodaro ET, Patel E, Price D, Nelson PT, Bachstetter AD. Dystrophic microglia are associated with neurodegenerative disease and not healthy aging in the human brain. Neurobiol Aging. 2021 Jan 6;99:19-27. doi: 0.1016/j.neurobiolaging.2020.12.003. PMID: 33422891

Attems J, Toledo JB, Walker L, Gelpi E, Gentleman S, Halliday G, Hortobagyi T, Jellinger K, Kovacs GG, Lee EB, Love S, McAleese KE, Nelson PT, Neumann M, Parkkinen L, Polvikoski T, Sikorska B, Smith C, Grinberg LT, Thal DR, Trojanowski JQ, McKeith IG.Acta Neuropathol. Neuropathological consensus criteria for the evaluation of Lewy pathology in post-mortem brains: a multi-centre study. 2021 Jan 5. doi: 10.1007/s00401-020-02255-2. PMID: 33399945

Bao WD, Pang P, Zhou XT, Hu F, Xiong W, Chen K, Wang J, Wang F, Xie D, Hu YZ, Han ZT, Zhang HH, Wang WXNelson PT, Chen JG, Lu Y, Man HY, Liu D, Zhu LQ. Loss of ferroportin induces memory impairment by promoting ferroptosis in Alzheimer's disease. Cell Death Differ. 2021 Jan 4. doi: 10.1038/s41418-020-00685-9. PMID: 33398092 

Niedowicz DM, Wang-Xia Wang, Price DA, Nelson PT (2021) Modulating Thyroid Hormone Levels in Adult Mice: Impact on Behavior and Compensatory Brain Changes. J. Thyroid Res.

O'Connor W, Ferreira J (2021). Autopsy Proven T lymphocyte Mediated Myocarditis as a Complication of SARS-CoV-2 Infection. CAP21 September 25-28, 2021. Archives of Pathology & Laboratory Medicine;*

Babady NE, L Bourassa, C-AD Burnham, M Fisher, E McElvania, CR Polage, JA Ribes. 2021. Multicenter evaluation of processing and analysis of College of American Pathologists (CAP) proficiency testing samples by laboratory automation. J Clin Microbiol 59:e03233-20.

Al-Obaidy KI, Williamson SR, Shelman N, Idrees MT, Ulbright TM. Hepatoid Teratoma, Hepatoid Yolk Sac Tumor, and Hepatocellular Carcinoma: A Morphologic and Immunohistochemical Study of 30 Cases. Am J Surg Pathol. 2021 Jan;45(1):127-136.

Gatineau E, Arthur G, Poupeau A, Nichols K, Spear BT, Shelman NR, Graf GA, Temel RE, Yiannikouris FB. The prorenin receptor and its soluble form contribute to lipid homeostasis. Am J Physiol Endocrinol Metab. 2021 Mar 1;320(3):E609-E618.

O'Brien KJ, Parisi X, Shelman NR, Merideth MA, Introne WJ, Heller T, Gahl WA, Malicdan MCV, Gochuico BR. Inflammatory bowel disease in Hermansky-Pudlak syndrome: a retrospective single-centre cohort study. J Intern Med. 2021 Jul; 290(1):129-140.

Wang-Xia Wang, Prajapati P, Vekaria HJ, Spry M, Cloud AL, Sullivan PG, and Springer JE. (2021) Temporal changes in inflammatory mitochondria-enriched microRNAs following traumatic brain injury and effects of miR-146a nanoparticle delivery. Neural Regen Res. 2021 Mar;16(3):514-522. doi:10.4103/1673-5374.293149. PMID: 32985480 (Co-corresponding author). Cited by: 1 (source: Google Scholar)

Wang-Xia Wang, Springer JE, Xie K, Fardo DW, and Hatton KW (2021) A Highly Predictive MicroRNA Panel for Determining Delayed Cerebral Vasospasm Risk Following Aneurysmal Subarachnoid Hemorrhage. Front. Mol. Biosci. 8:657258. doi: 10.3389/fmolb.2021.657258 (Co-corresponding author) 

Asamoah A, Wei S, Jackson K, Hersh J and Levy H. Diagnosis of Classic Homocystinuria in 2 boys presenting with acute cerebral venous thrombosis and neurologic dysfunction after normal newborn screening Int J Neonatal Screen 2021 submitted. doi: 10.3390/ijns7030048. PMID: 34449521.