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In addition to providing high quality health care, the University of Kentucky is also committed to finding new treatments, tests, and cures for diseases. Now, patients at UK can contribute to that effort by agreeing to participate in the Research Registry and Specimen Bank, or the "biobank." When you have a medical procedure that involves, for example, drawing blood or sampling tissue, there is often material left over from the testing process that would otherwise be thrown away.
Nearly 700 researchers, students, policymakers and community members will gather at the Lexington Convention Center March 27 to share research, mentor junior faculty, and enhance collaborations in clinical and translational science, with special focus on addressing health disparities in Appalachia.
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University of Kentucky College of Medicine student Melanie Pleiss has received the PhRMA Foundation Pre-Doctoral Fellowship in Pharmacology/Toxicology. The fellowship is a two year award that provides recipients with an annual stipend of $20,000 to support the research activities of a doctoral program. "The application process is extremely competitive, with just one applicant per institution allowed to apply and only a certain number of awards given to U.S. schools of medicine, pharmacy, dentistry or veterinary medicine," said Dr.
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For junior faculty with clinical and/or teaching responsibilities, it's difficult to find enough time to prioritize their own research. On top of time constraints, junior faculty members often have limited experience in the precise art of writing successful federal grant applications and managing large grants. It takes time, training, and funding to accelerate a research career. The KL2 Career Development Program provides these resources to investigators to do just that.
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A new study led by University of Kentucky Markey Cancer Center researcher Peter Zhou shows that targeting Twist, a nuclear protein that is an accelerant of the epithelial-mesenchymal transition (EMT) program in human cells, may provide an effective approach for treating triple-negative breast cancer. Triple-negative breast cancer has an activated EMT program, which is a process that provides cells with the increased plasticity (or flexibility) to adapt to stressed environments during embryonic development, wound healing, tissue fibrosis and metastasis.
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A new study by University of Kentucky researchers shows that women who never or rarely screen for breast cancer are also unlikely to receive screening for cervical cancer. The study also identified four key barriers independently associated with the lack of these cancer screenings in Appalachian women. Published in Women & Health, the study focused on six rural counties in Appalachian Kentucky. Researchers conducted in-person interviews with 222 women to assess their adherence (or lack thereof) to cancer screening guidelines.
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There's a proverb in the business world that says, "If you don’t know, hire someone who does." In the world of translational research, the saying might go like something this: "If you don't have the expertise or resources, collaborate with someone who does." The nature of translational science -- the process of turning a basic science discovery into applications for human patients -- is inherently multidimensional.
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In a time when competition for federal research funding  is tougher than ever before, the University of Kentucky has been awarded one of the largest health grants ever made to the institution: an $11.3 million National Institutes of Health (NIH) grant  supporting research focusing on issues that plague the Commonwealth - the twin scourges of obesity and cardiovascular disease.

Everyone wants to be home for the holidays. Unfortunately, hospital patients don't have that luxury. For those who are unable to enjoy the comforts of a holiday at home, the UK Arts in Healthcare program has scheduled a series of events to help bring the holidays to the hospital. Carolers, pianists, harpists and more will bring holiday cheer to patients, visitors and staff in December. Of particular note: UK HealthCare's own Dr. Jay Zwischenberger will be performing at 1 p.m., Dec.
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A new clinical trial being conducted at the University of Kentucky Sanders-Brown Center on Aging (SBCoA) and the UK Alzheimer’s Disease Center (ADC) may signal new hope in the future for those who might be afflicted with the devastating disease. Taking laboratory research pioneered at SBCoA and the associated UK ADC into human trials, the federally-funded research project will examine the therapeutic potential of microRNAs to delay or prevent Alzheimer’s disease.

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Jayakrishna Ambati, professor and vice-chair in the Department of Ophthalmology and Visual Sciences, professor in the Department of Physiology, and the E. Vernon and Eloise C. Smith Endowed Chair in Macular Degeneration Research, at the University of Kentucky College of Medicine, recently received the 2013 William R. Willard Dean's Recognition Award.
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Singer, physician, athlete and inspirational speaker Dr. Ronan Tynan is no stranger to adversity. When Tynan was 20, his legs had to be amputated below the knee after an auto accident caused serious complications. Just weeks after the operation, he was climbing up the steps of his college dorm, and within a year, he was winning gold medals in the Paralympics as a multitalented athlete. Between 1981 and 1984, Tynan amassed 18 gold medals and 14 world records, of which he still holds nine.
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The University of Kentucky Center for Clinical and Translational Science will host the 2nd Annual UK Clinical Research Education Day on Friday, Oct. 25, from 9 a.m. to 3 p.m. in the UK Chandler Hospital, Pavilion H North Lobby (outside of the administration offices).
The University of Kentucky Center for Clinical and Translational Science (CCTS) Pilot Funding Program announces recipients of its most recent round of pilot funding in the Collaborative Category.
The "Triple Crown" is a term reserved for the greatest accomplishment in thoroughbred racing -- winning the Kentucky Derby, Preakness Stakes and Belmont Stakes.
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The University of Kentucky Gill Heart Institute and the UK Saha Cardiovascular Research Center will host the 16th Annual Gill Heart Cardiovascular Research Day, Oct. 11, at the Lexington Convention Center. Gill Heart Insitute Cardiovascular Research Day annually attracts preeminent speakers in the field of cardiology and cardiovascular research. It also features a symposium for trainee researchers, a scientific poster session, and the presentation of the annual Saha Awards for medical and nursing education. This year, speakers include Dr.

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You may not know the human metapneumovirus by name, but chances are that you have met somewhere before.

HMPV, as it's known to virologists, is a common respiratory virus that new studies suggest is second only to influenza in the number of viral pneumonia cases it causes worldwide every year. Especially dangerous for small children, the elderly, and anyone with a compromised immune system, the virus strikes almost 100 percent of people on Earth at some point in their lives.

What if we could pinpoint a hereditary cause for Alzheimer's, and intervene to reduce the risk of the disease? We may be closer to that goal, thanks to a team at the University of Kentucky. Researchers affiliated with the UK Sanders-Brown Center on Aging have completed new work in Alzheimer's genetics; the research is detailed in a paper published today in the Journal of Neuroscience. Emerging evidence indicates that, much like in the case of high cholesterol, some Alzheimer's disease risk is inherited while the remainder is environmental.
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As a native Kentuckian, the University of Kentucky Markey Cancer Center's Dr. Susanne Arnold understands many of the health issues our state faces — and focusing on the problems that hit hardest close to home has kept her motivated in her work.

"I got into research in Appalachia because I'm an eighth-generation Kentuckian, and my father, who was also a doctor and researcher, was a seventh-generation Kentuckian," Arnold said. "I learned a very valuable lesson from him — that we can't make progress in the treatment of diseases without being invested in the research that we do."

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The University of Kentucky Markey Cancer Center was joined by national, state and local leaders today to celebrate its designation as a National Cancer Institute cancer center. The UK Markey Cancer Center is the 68th medical center in the country to receive this prestigious designation, and is the only NCI-designated cancer center in the state of Kentucky. "Kentucky’s extraordinarily high cancer rates cause untold suffering within our families," said Kentucky Gov. Steve Beshear.