Profile picture for user cgva222

Craig van Horne, MD, PhD


800 Rose Street, Rm: MS103B, Lexington, KY


  • Professor of Neurosurgery
  • Chairman, Department of Neurosurgery
  • Co-Director, Brain Restoration Center
  • Virginia T. Barrow Endowed Chair
  • CAST Stereotactic and Functional Fellowship Director

College Unit(s)

Other Affiliation(s)
  • Neuroscience - Joint Faculty

Biography and Education


Dr. Craig van Horne is a nationally and internationally recognized expert in neurosurgery who specializes in the diagnosis and treatment of movement disorders. His research focuses on innovative surgical treatment strategies for Parkinson’s disease. Since his days as an undergraduate, van Horne has been interested in neuro-regeneration and the treatment of Parkinson’s disease. While working on his bachelor’s degree in biology at Williams College in Massachusetts, he completed an honors thesis in neurobiology, transplanting peripheral nerve tissue to the central nervous system in goldfish. During his MD-PhD studies at the University of Colorado, van Horne expanded his work on neuro-transplantation for his doctoral thesis, focusing on an animal model of Parkinson’s disease. Van Horne completed his residency in neurosurgery at Brigham and Women’s Hospital in Boston, where he later served on the neurosurgery faculty. After 20 years in Boston, he moved to Kentucky to join UK HealthCare, where he practices as a neurosurgeon and serves as co-director of the Brain Restoration Center (BRC), part of the Kentucky Neuroscience Institute. As a leader of the BRC, van Horne collaborates with a multidisciplinary team that is helping patients find relief from movement disorder symptoms while also pursuing innovative treatments in the fight against Parkinson’s. Van Horne is the Virginia T. Barrow Endowed Chair at UK and a professor of neurosurgery in the UK College of Medicine. He is currently leading a first-of-its-kind clinical study on “DBS+,” a novel approach to Parkinson’s treatment that involves transplanting peripheral nerve tissue into the brain during deep brain stimulation (DBS) surgery.


Dr. van Horne is a Professor in the Department of Neurosurgery at the University of Kentucky. He graduated from the University of Colorado School of Medicine with an MD as well as a PhD in treatment strategies for Parkinson's disease. He completed his residency training in Neurosurgery at Brigham and Women's Hospital in Boston, Massachusetts. Dr. van Horne is Board Certified by the American Board of Neurological Surgery and is nationally and internationally recognized as an expert in Neurosurgery. Dr. van Horne has extensive experience in the diagnosis and treatment of movement disorders. He specialized in Deep Brain Stimulation for Parkinson's disease and other movement disorders. His current research focuses on innovative and novel surgical treatment strategies for Parkinson's disease. Faculty Rank Professor of Neurosurgery Degree University of Colorado School of Medicine, Aurora Residency Brigham and Women's Hospital, Harvard Medical School, Boston Certifications and Special Training American Board of Neurological Surgery


van Horne Lab

Brain Restoration Center (BRC)


Current Research:

APNG - Project IV
Principal Investigator: Craig van Horne, MD, PhD
Coordinator: Morgan Yazell
Status: Open to Enrollment
Title: Continuation of a Pilot Study to Evaluate the Safety and Feasibility of Implanting Autologous Peripheral Nerve Grafts in Subjects with Parkinson's disease Undergoing Deep Brain Stimulation Surgery and Treatment: Multisite-Delivery Sub-Study

DBS Eval
Principal Investigator: Craig van Horne, MD, PhD
Coordinator: Morgan Yazell
Status: Open to Enrollment
Title: Evaluation of Deep Brain Stimulation Therapy in Patients with Parkinson's Disease
Purpose: To follow the progression of Parkinson's disease in people who have received DBS and examine DBS therapy in patients who have had DBS


Team Members:

  • Craig van Horne, MD, PhD
  • Greg Gerhardt, PhD
  • George Quintero, PhD
  • Morgan Yazell
  • Jaimie L. Hixson

Selected Publications

Research Gate Pubmed Publications