Profile picture for user alsi242

Aaron Silverstein, PhD

Connect

alsi242@uky.edu

Positions

  • MD/PhD Student

College Unit(s)

Other Affiliation(s)
  • Neuroscience
  • SCOBIRC - Graduate Student
  • MD/PhD Program

Biography and Education

Education

Aaron Silverstein is an MD/PhD candidate and fourth-year medical student at the University of Kentucky pursuing a career in neurosurgery, with particular interests in spine surgery, neurotrauma, and translational spinal cord injury research. Under the mentorship of Dr. Warren Alilain, his PhD work focused on spinal cord injury, neuroinflammation, intermittent hypoxia therapy, and improving the clinical relevance of rodent neurotrauma models through incorporation of neurosurgical standards of care. Aaron is originally from Paducah, Kentucky, and completed undergraduate degrees in Neuroscience and Psychology at the University of Kentucky, along with a minor in Violin Performance. Outside of medicine and research, he enjoys running, strength training, serving as a violinist at his church, watching MMA, and spending time with his wife, Kelsey, and their two young children.

Summary:

Current Year: M3
Ph.D. Neuroscience, B.S. Neuroscience, B.S. Psychology - Univ. KY
Hometown: Paducah, KY

Selected Publications

  • Silverstein, A.L., Calulot, C. M., McLouth, C., Gensel, J. C., and Alilain, W. J. (2026) CatWalk XT enables sensitive detection of locomotor deficits after C2 hemisection and integrates readily into ongoing experimental workflows in adult female rats. Neurotrauma Reports. Feb;7:1 doi: 10.1177/2689288X261418910.
  • Silverstein AL, Calulot CM, McLouth CJ, Gensel JC, Alilain WJ. (2026) Liposome-encapsulated clodronate and   COX-2  inhibitor treatment impair ventilatory recovery but improve compensatory locomotor function following cervical spinal cord injury in rats. Exp Neurol. Feb;396:115522. doi:10.1016/j.expneurol.2025.115522. 
  • Silverstein, A.L. and Alilain, W. J. (2024) Ethanol abolishes ventilatory long-term facilitation and blunts the ventilatory response to hypoxia in female rats. Respir Physiol Neurobiol. Epub ahead of print. doi: 10.1016/j.resp.2024.104373.
  • Silverstein, A. L., Lawson, K. G., Farhadi, F., & Alilain, W. (2023). Contrasting experimental rodent aftercare with human clinical treatment for cervical spinal cord injury: Bridging the translational "Valley of Death". J Neurotrauma. doi:10.1089/neu.2023.0314
  • Silverstein, A.L. and Alilain, W.J. (2021) Intermittent hypoxia induces greater functional breathing motor recovery as a fixed rather than varied duration treatment after cervical spinal cord injury in rats. Neurotrauma Reports 2:1, 343–353, DOI:10.1089/neur.2021.0004.
  • Maddie Stanback, Alexandra E. Stanback, Saadia Akhtar, Ross Basham, Bharath Chithrala, Bennett Collis, Bernardo Aguzzoli Heberle, Emma Higgins, Allison Lane, Saisindhu Marella, Matthew Ponder, Prachi Raichur, Aaron Silverstein, Catherine Stanley, Kelsi Vela, and Robin L. Cooper. (2019). The Effect of Lipopolysaccharides on Primary Sensory Neurons in Crustacean Models. Impulse (Columbia, S.C.).
PubMed Search Results Publication not indexed on PubMed, available from the Directory of Open Access Journals