MD/PhD Program Current Students Recent Student Publications Publications by Alumni Publications by Alumni Andres Chang, MD, PhD Andres Chang, MD, PhD Determinants of Neutralizing Antibody Response After SARS CoV-2 Vaccination in Patients With Myeloma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology Andres Chang 2022 Mar 8 Antibody response to SARS-CoV-2 mRNA vaccine in lung cancer patients: Reactivity to vaccine antigen and variants of concern. medRxiv : the preprint server for health sciences Andres Chang 2022 Jan 23 Humoral Responses Against SARS-CoV-2 and Variants of Concern After mRNA Vaccines in Patients With Non-Hodgkin Lymphoma and Chronic Lymphocytic Leukemia. Journal of clinical oncology : official journal of the American Society of Clinical Oncology Andres Chang 2022 Apr 18 Influenza Vaccination Rates Among Patients With a History of Cancer: Analysis of the National Health Interview Survey. Open forum infectious diseases Andres Chang 2021 Jul Gene expression profiling-based risk prediction and profiles of immune infiltration in diffuse large B-cell lymphoma. Blood cancer journal Andres Chang 2021 Jan 7 Remaining challenges in predicting patient outcomes for diffuse large B-cell lymphoma. Expert review of hematology Andres Chang 2019 Nov Human metapneumovirus fusion protein triggering: Increasing complexities by analysis of new HMPV fusion proteins. Virology Andres Chang 2019 May Challenges in the treatment and prevention of delayed hemolytic transfusion reactions with hyperhemolysis in sickle cell disease patients. Transfusion Andres Chang 2019 May Influenza Vaccination Documentation Rates During the First Year After Diagnosis of Diffuse Large B Cell Lymphoma. Clinical lymphoma, myeloma & leukemia Andres Chang 2019 Apr Myocarditis With Radiotherapy and Immunotherapy in Multiple Myeloma. Journal of oncology practice Andres Chang 2018 Sep The step-like evolution of Arctic open water. Scientific reports Andres Chang 2018 Nov 15 Investigational PD-1 inhibitors in HL and NHL and biomarkers for predictors of response and outcome. Expert opinion on investigational drugs Andres Chang 2018 Jan Romulo Albuquerque, MD, PhD Romulo Albuquerque, MD, PhD Chronic Dicer1 deficiency promotes atrophic and neovascular outer retinal pathologies in mice. Proceedings of the National Academy of Sciences of the United States of America Romulo Albuquerque, MD, PhD 2020 Feb 4 Latent Sensitization in a Mouse Model of Ocular Neuropathic Pain. Translational vision science & technology Romulo Albuquerque, MD, PhD 2019 Mar Lucas Scott Broster, MD, PhD Lucas Scott Broster, MD, PhD Assessing adolescent tobacco use in a substance use treatment program with self-report and biological measures. Addictive behaviors Lucas Scott Broster 2020 Aug Spared behavioral repetition effects in Alzheimer's disease linked to an altered neural mechanism at posterior cortex. Journal of clinical and experimental neuropsychology Lucas Scott Broster 2018 Oct Predicting risk decisions in a modified Balloon Analogue Risk Task: Conventional and single-trial ERP analyses. Cognitive, affective & behavioral neuroscience Lucas Scott Broster 2018 Feb Electrophysiological repetition effects in persons with mild cognitive impairment depend upon working memory demand. Neuropsychologia Lucas Scott Broster 2018 Aug Neural substrates of context- and person-dependent altruistic punishment. Human brain mapping Lucas Scott Broster 2017 Nov Valence and magnitude ambiguity in feedback processing. Brain and behavior Lucas Scott Broster 2017 May A cognitive electrophysiological signature differentiates amnestic mild cognitive impairment from normal aging. Alzheimer's research & therapy Lucas Scott Broster 2017 Jan 19 Impulsive personality dimensions are associated with altered behavioral performance and neural responses in the monetary incentive delay task. Neuropsychologia Lucas Scott Broster 2017 Aug Functional human <i>GRIN2B</i> promoter polymorphism and variation of mental processing speed in older adults. Aging Lucas Scott Broster 2017 Apr Low Arousal Positive Emotional Stimuli Attenuate Aberrant Working Memory Processing in Persons with Mild Cognitive Impairment. Journal of Alzheimer's disease : JAD Lucas Scott Broster 2017 Evidence that the Human Innate Immune Peptide LL-37 may be a Binding Partner of Amyloid-β and Inhibitor of Fibril Assembly. Journal of Alzheimer's disease : JAD Lucas Scott Broster 2017 Trait Anxiety and Economic Risk Avoidance Are Not Necessarily Associated: Evidence from the Framing Effect. Frontiers in psychology Lucas Scott Broster 2017 Chris Brown, MD, PhD Chris Brown, MD, PhD Intubation practice and outcomes among pediatric emergency departments: A report from National Emergency Airway Registry for Children (NEAR4KIDS). Academic emergency medicine : official journal of the Society for Academic Emergency Medicine Chris Brown 2022 Apr Sustained Improvement in Tracheal Intubation Safety Across a 15-Center Quality-Improvement Collaborative: An Interventional Study From the National Emergency Airway Registry for Children Investigators. Critical care medicine Chris Brown 2021 Feb 1 Thermoneutrality Alters Gastrointestinal Antigen Passage Patterning and Predisposes to Oral Antigen Sensitization in Mice. Frontiers in immunology Chris Brown 2021 Antagonism between substitutions in β-lactamase explains a path not taken in the evolution of bacterial drug resistance. The Journal of biological chemistry Chris Brown 2020 May 22 Antagonism between substitutions in β-lactamase explains a path not taken in the evolution of bacterial drug resistance. The Journal of biological chemistry Chris Brown 2020 May 22 Education does not protect cognitive function from brain pathology in the ADNI 2 cohort. Neurobiology of aging Chris Brown 2020 Jun Comparison of Upper Respiratory Viral Load Distributions in Asymptomatic and Symptomatic Children Diagnosed with SARS-CoV-2 Infection in Pediatric Hospital Testing Programs. Journal of clinical microbiology Chris Brown 2020 Dec 17 Distinct patterns of default mode and executive control network circuitry contribute to present and future executive function in older adults. NeuroImage Chris Brown 2019 Jul 15 Age and Alzheimer's pathology disrupt default mode network functioning via alterations in white matter microstructure but not hyperintensities. Cortex; a journal devoted to the study of the nervous system and behavior Chris Brown 2018 Jul Distinct White Matter Changes Associated with Cerebrospinal Fluid Amyloid-β1-42 and Hypertension. Journal of Alzheimer's disease : JAD Chris Brown 2018 Clinically silent Alzheimer's and vascular pathologies influence brain networks supporting executive function in healthy older adults. Neurobiology of aging Chris Brown 2017 Oct Development, validation and application of a new fornix template for studies of aging and preclinical Alzheimer's disease. NeuroImage. Clinical Chris Brown 2017 James Butler, MD, PhD James Butler, MD, PhD Abdominal functional electrical stimulation to assist ventilator weaning in critical illness: a double-blinded, randomised, sham-controlled pilot study. Critical care (London, England) James Butler, MD, PhD 2019 Jul 24 Gregory E Cooper, MD, PhD Gregory E Cooper, MD, PhD Tobacco Smoking and Dementia in a Kentucky Cohort: A Competing Risk Analysis. Journal of Alzheimer's disease : JAD Gregory E Cooper, MD, PhD 2019 Genomic sequencing identifies secondary findings in a cohort of parent study participants. Genetics in medicine : official journal of the American College of Medical Genetics Gregory E Cooper, MD, PhD 2018 Dec Dena Dubal, MD, PhD Dena Dubal, MD, PhD KL1 Domain of Longevity Factor Klotho Mimics the Metabolome of Cognitive Stimulation and Enhances Cognition in Young and Aging Mice. The Journal of neuroscience : the official journal of the Society for Neuroscience Dena Dubal, MD, PhD 2022 May 11 KIBRA, MTNR1B, and FKBP5 genotypes are associated with decreased odds of incident delirium in elderly post-surgical patients. Scientific reports Dena Dubal, MD, PhD 2022 Jan 11 Sex-Stratified Single-Cell RNA-Seq Analysis Identifies Sex-Specific and Cell Type-Specific Transcriptional Responses in Alzheimer's Disease Across Two Brain Regions. Molecular neurobiology Dena Dubal, MD, PhD 2022 Jan Sex-Specific Association of the X Chromosome With Cognitive Change and Tau Pathology in Aging and Alzheimer Disease. JAMA neurology Dena Dubal, MD, PhD 2021 Oct 1 Circulating klotho is elevated in cerebrospinal fluid, but not serum, among KLOTHO KL-VS allele carriers at risk for Alzheimer's disease. Alzheimer's & dementia : the journal of the Alzheimer's Association Dena Dubal, MD, PhD 2021 Dec The Interaction between Ventricle to Brain Ratio and Serum Klotho on Cognition in Older Adults at Risk for Alzheimer's Disease. Alzheimer's & dementia : the journal of the Alzheimer's Association Dena Dubal, MD, PhD 2021 Dec Sugar sweetened beverage consumption is positively associated with Klotho levels at two years of age in LatinX youth. BMC nutrition Dena Dubal, MD, PhD 2021 Apr 23 Age-Related Tau Burden and Cognitive Deficits Are Attenuated in KLOTHO KL-VS Heterozygotes. Journal of Alzheimer's disease : JAD Dena Dubal, MD, PhD 2021 Effects of Aerobic Exercise Training on Systemic Biomarkers and Cognition in Late Middle-Aged Adults at Risk for Alzheimer's Disease. Frontiers in endocrinology Dena Dubal, MD, PhD 2021 Age-Related Tau Burden and Cognitive Deficits Are Attenuated in KLOTHO KL-VS Heterozygotes. Journal of Alzheimer's disease : JAD Dena Dubal, MD, PhD 2021 Best of JAMA Neurology 2019: Research That Drives Practice. JAMA neurology Dena Dubal, MD, PhD 2020 Mar 1 Longevity Gene KLOTHO and Alzheimer Disease-A Better Fate for Individuals Who Carry APOE ε4. JAMA neurology Dena Dubal, MD, PhD 2020 Jul 1 A second X chromosome contributes to resilience in a mouse model of Alzheimer's disease. Science translational medicine Dena Dubal, MD, PhD 2020 Aug 26 Sexual dimorphism of physical activity on cognitive aging: Role of immune functioning. Brain, behavior, and immunity Dena Dubal, MD, PhD 2020 Aug Sex difference in Alzheimer's disease: An updated, balanced and emerging perspective on differing vulnerabilities. Handbook of clinical neurology Dena Dubal, MD, PhD 2020 Pathways to brain resilience. Nature medicine Dena Dubal, MD, PhD 2019 Jul Female XX sex chromosomes increase survival and extend lifespan in aging mice. Aging cell Dena Dubal, MD, PhD 2019 Feb <i>KLOTHO</i> heterozygosity attenuates <i>APOE4</i>-related amyloid burden in preclinical AD. Neurology Dena Dubal, MD, PhD 2019 Apr 16 Neural-Derived Extracellular Vesicles in Clinical Trials: Message in a Bottle. JAMA neurology Dena Dubal, MD, PhD 2019 Apr 1 Ovarian Cycle Stages Modulate Alzheimer-Related Cognitive and Brain Network Alterations in Female Mice. eNeuro Dena Dubal, MD, PhD 2018 Nov-Dec The Way of Tau: Secretion and Synaptic Dysfunction. Trends in molecular medicine Dena Dubal, MD, PhD 2018 Jul Cord blood klotho levels are inversely associated with leptin in healthy Latino neonates at risk for obesity. Journal of pediatric endocrinology & metabolism : JPEM Dena Dubal, MD, PhD 2018 Apr 25 Apolipoprotein E ε4 and Risk Factors for Alzheimer Disease-Let's Talk About Sex. JAMA neurology Dena Dubal, MD, PhD 2017 Oct 1 <i>BDNF</i> Val66Met predicts cognitive decline in the Wisconsin Registry for Alzheimer's Prevention. Neurology Dena Dubal, MD, PhD 2017 May 30 Peripheral Elevation of a Klotho Fragment Enhances Brain Function and Resilience in Young, Aging, and α-Synuclein Transgenic Mice. Cell reports Dena Dubal, MD, PhD 2017 Aug 8 Systemic klotho is associated with KLOTHO variation and predicts intrinsic cortical connectivity in healthy human aging. Brain imaging and behavior Dena Dubal, MD, PhD 2017 Apr Benjamin J Fowler, MD, PhD Benjamin J Fowler, MD, PhD cGAS drives noncanonical-inflammasome activation in age-related macular degeneration. Nature medicine Benjamin J Fowler 2018 Jan NLRP3 inflammasome activation by mycobacterial ESAT-6 and dsRNA in intraocular tuberculosis. Microbial pathogenesis Benjamin J Fowler 2018 Jan Zachary Fulkerson, MD, PhD Zachary Fulkerson, MD, PhD Implementation of a point-of-care ultrasound skills practicum for hospitalists. Ultrasound (Leeds, England) Zachary Fulkerson 2019 Feb Thrombocytopenia and disseminated histoplasmosis in immunocompetent adults. Clinical case reports Zachary Fulkerson 2017 Dec Gregory N Barnes, MD, PhD Gregory N Barnes, MD, PhD Potential crosstalk between sonic hedgehog-WNT signaling and neurovascular molecules: Implications for blood-brain barrier integrity in autism spectrum disorder. Journal of neurochemistry Gregory N Barnes, MD, PhD 2021 Oct A robust DWT-CNN-based CAD system for early diagnosis of autism using task-based fMRI. Medical physics Gregory N Barnes, MD, PhD 2021 May Dynamic glial response and crosstalk in demyelination-remyelination and neurodegeneration processes. Neural regeneration research Gregory N Barnes, MD, PhD 2021 Jul The Role of Diffusion Tensor MR Imaging (DTI) of the Brain in Diagnosing Autism Spectrum Disorder: Promising Results. Sensors (Basel, Switzerland) Gregory N Barnes, MD, PhD 2021 Dec 7 A Personalized Computer-Aided Diagnosis System for Mild Cognitive Impairment (MCI) Using Structural MRI (sMRI). Sensors (Basel, Switzerland) Gregory N Barnes, MD, PhD 2021 Aug 11 Platelet-Activating Factor Deteriorates Lysophosphatidylcholine-Induced Demyelination Via Its Receptor-Dependent and -Independent Effects. Molecular neurobiology Gregory N Barnes, MD, PhD 2020 Oct Publisher Correction: Cadmium and High-Fat Diet Disrupt Renal, Cardiac and Hepatic Essential Metals. Scientific reports Gregory N Barnes, MD, PhD 2020 Feb 10 Disruption of essential metal homeostasis in the brain by cadmium and high-fat diet. Toxicology reports Gregory N Barnes, MD, PhD 2020 Neuroprotective Effects of Adenosine A1 Receptor Signaling on Cognitive Impairment Induced by Chronic Intermittent Hypoxia in Mice. Frontiers in cellular neuroscience Gregory N Barnes, MD, PhD 2020 Dynamic response of microglia/macrophage polarization following demyelination in mice. Journal of neuroinflammation Gregory N Barnes, MD, PhD 2019 Oct 17 Cadmium and High-Fat Diet Disrupt Renal, Cardiac and Hepatic Essential Metals. Scientific reports Gregory N Barnes, MD, PhD 2019 Oct 11 A randomized controlled trial of levodopa in patients with Angelman syndrome. American journal of medical genetics. Part A Gregory N Barnes, MD, PhD 2018 May Neuroimmunologic and Neurotrophic Interactions in Autism Spectrum Disorders: Relationship to Neuroinflammation. Neuromolecular medicine Gregory N Barnes, MD, PhD 2018 Jun Alzheimer's disease diagnostics by a 3D deeply supervised adaptable convolutional network. Frontiers in bioscience (Landmark edition) Gregory N Barnes, MD, PhD 2018 Jan 1 Medical imaging diagnosis of early Alzheimer's disease. Frontiers in bioscience (Landmark edition) Gregory N Barnes, MD, PhD 2018 Jan 1 A Novel Early Diagnosis System for Mild Cognitive Impairment Based on Local Region Analysis: A Pilot Study. Frontiers in human neuroscience Gregory N Barnes, MD, PhD 2017 A fast stochastic framework for automatic MR brain images segmentation. PloS one Gregory N Barnes, MD, PhD 2017 Christina S Hines, MD, PhD Christina S Hines, MD, PhD Identifying generalized anxiety disorder using resting state habenular circuitry. Brain imaging and behavior Christina S Hines, MD, PhD 2020 Oct Frontoparietal network abnormalities of gray matter volume and functional connectivity in patients with generalized anxiety disorder. Psychiatry research. Neuroimaging Christina S Hines, MD, PhD 2019 Apr 30 Joshua L Hood, MD, PhD Joshua L Hood, MD, PhD A reducible comparison of 2D vs. 3D HepG2 culture-derived sEV characteristics and cancer pathway-related miRNA content. FASEB journal : official publication of the Federation of American Societies for Experimental Biology Joshua L Hood, MD, PhD 2022 May Separation of U87 glioblastoma cell-derived small and medium extracellular vesicles using elasto-inertial flow focusing (a spiral channel). Scientific reports Joshua L Hood, MD, PhD 2022 Apr 12 Ginger nanoparticles mediated induction of Foxa2 prevents high-fat diet-induced insulin resistance. Theranostics Joshua L Hood, MD, PhD 2022 Development and Testing of a Continuous Flow-Electrical-Split-Flow Lateral Transport Thin Separation System (Fl-El-SPLITT). Analytical chemistry Joshua L Hood, MD, PhD 2021 Feb 9 Characterization of Human Glioblastoma versus Normal Plasma-Derived Extracellular Vesicles Preisolated by Differential Centrifugation Using Cyclical Electrical Field-Flow Fractionation. Analytical chemistry Joshua L Hood, MD, PhD 2020 Jul 21 Hemoglobin Genotypes Modulate Inflammatory Response to <i>Plasmodium</i> Infection. Frontiers in immunology Joshua L Hood, MD, PhD 2020 Detection of Inflammation-Related Melanoma Small Extracellular Vesicle (sEV) mRNA Content Using Primary Melanocyte sEVs as a Reference. International journal of molecular sciences Joshua L Hood, MD, PhD 2019 Mar 12 Natural melanoma-derived extracellular vesicles. Seminars in cancer biology Joshua L Hood, MD, PhD 2019 Dec Exosome Isolation: Cyclical Electrical Field Flow Fractionation in Low-Ionic-Strength Fluids. Analytical chemistry Joshua L Hood, MD, PhD 2018 Nov 6 Pre-analytical influences on the population heterogeneity of human extracellular vesicles sourced for nanomedicine uses. Nanomedicine (London, England) Joshua L Hood, MD, PhD 2018 Nov Melanoma exosomes promote mixed M1 and M2 macrophage polarization. Cytokine Joshua L Hood, MD, PhD 2018 May The association of exosomes with lymph nodes. Seminars in cell & developmental biology Joshua L Hood, MD, PhD 2017 Jul Carmen Kiper, MD, PhD Carmen Kiper, MD, PhD Mitral Valve Replacement in Pediatrics Using an Extracellular Matrix Cylinder Valve: A Case Series. Pediatric cardiology Carmen Kiper, MD, PhD 2020 Oct Echocardiographic diagnosis of atrial flutter in a neonate. Echocardiography (Mount Kisco, N.Y.) Carmen Kiper, MD, PhD 2018 Sep Residents leading the way: a unique advocacy programme. Medical education Carmen Kiper, MD, PhD 2018 May Caitlin Latimer, MD. PhD Caitlin Latimer, MD. PhD Decoding perineuronal net glycan sulfation patterns in the Alzheimer's disease brain. Alzheimer's & dementia : the journal of the Alzheimer's Association Caitlin Latimer, MD. PhD 2022 May Progress in Amyotrophic Lateral Sclerosis Gene Discovery: Reflecting on Classic Approaches and Leveraging Emerging Technologies. Neurology. Genetics Caitlin Latimer, MD. PhD 2022 Jun Author Correction: Human neocortical expansion involves glutamatergic neuron diversification. Nature Caitlin Latimer, MD. PhD 2022 Jan Genome-wide association study and functional validation implicates JADE1 in tauopathy. Acta neuropathologica Caitlin Latimer, MD. PhD 2022 Jan Glial TDP-43 and TDP-43 induced glial pathology, focus on neurodegenerative proteinopathy syndromes. Glia Caitlin Latimer, MD. PhD 2022 Feb Spinal cord-predominant neuropathology in an adult-onset case of POLR3A-related spastic ataxia. Neuropathology : official journal of the Japanese Society of Neuropathology Caitlin Latimer, MD. PhD 2022 Feb TDP-43 promotes tau accumulation and selective neurotoxicity in bigenic Caenorhabditis elegans. Disease models & mechanisms Caitlin Latimer, MD. PhD 2022 Apr 1 Human neocortical expansion involves glutamatergic neuron diversification. Nature Caitlin Latimer, MD. PhD 2021 Oct Isoform-specific dysregulation of AMP-activated protein kinase signaling in a non-human primate model of Alzheimer's disease. Neurobiology of disease Caitlin Latimer, MD. PhD 2021 Oct Application of deep learning to understand resilience to Alzheimer's disease pathology. Brain pathology (Zurich, Switzerland) Caitlin Latimer, MD. PhD 2021 Nov Aging-related Alzheimer's disease-like neuropathology and functional decline in captive vervet monkeys (Chlorocebus aethiops sabaeus). American journal of primatology Caitlin Latimer, MD. PhD 2021 Nov An Unusual Case of Proximal Limb Muscle Weakness. Arthritis & rheumatology (Hoboken, N.J.) Caitlin Latimer, MD. PhD 2021 Mar Pathological tau drives ectopic nuclear speckle scaffold protein SRRM2 accumulation in neuron cytoplasm in Alzheimer's disease. Acta neuropathologica communications Caitlin Latimer, MD. PhD 2021 Jun 29 Genetic Insights into Alzheimer's Disease. Annual review of pathology Caitlin Latimer, MD. PhD 2021 Jan 24 Distinct Poly(A) nucleases have differential impact on sut-2 dependent tauopathy phenotypes. Neurobiology of disease Caitlin Latimer, MD. PhD 2021 Jan Single-synapse analyses of Alzheimer's disease implicate pathologic tau, DJ1, CD47, and ApoE. Science advances Caitlin Latimer, MD. PhD 2021 Dec 17 Theoretical impact of the AT(N) framework on dementia using a community autopsy sample. Alzheimer's & dementia : the journal of the Alzheimer's Association Caitlin Latimer, MD. PhD 2021 Dec TDP-43 promotes pathological tau phosphorylation and selective neurotoxicity in C. elegans. Alzheimer's & dementia : the journal of the Alzheimer's Association Caitlin Latimer, MD. PhD 2021 Dec Tau and TDP-43 synergy: a novel therapeutic target for sporadic late-onset Alzheimer's disease. GeroScience Caitlin Latimer, MD. PhD 2021 Aug Leveraging Neuroimaging Tools to Assess Precision and Accuracy in an Alzheimer's Disease Neuropathologic Sampling Protocol. Frontiers in neuroscience Caitlin Latimer, MD. PhD 2021 Subdural Hematoma as a Serious Complication of Huntington's Disease: An Observational Study. Journal of Huntington's disease Caitlin Latimer, MD. PhD 2021 Fine Particulate Matter and Markers of Alzheimer's Disease Neuropathology at Autopsy in a Community-Based Cohort. Journal of Alzheimer's disease : JAD Caitlin Latimer, MD. PhD 2021 Metastatic Renal Cell Carcinoma Masquerading as a Sphenoid Wing Meningioma. Ophthalmic plastic and reconstructive surgery Caitlin Latimer, MD. PhD 2020 Sep/Oct Adult onset pan-neuronal human tau tubulin kinase 1 expression causes severe cerebellar neurodegeneration in mice. Acta neuropathologica communications Caitlin Latimer, MD. PhD 2020 Nov 23 Rapid Validation of Telepathology by an Academic Neuropathology Practice During the COVID-19 Pandemic. Archives of pathology & laboratory medicine Caitlin Latimer, MD. PhD 2020 Nov 1 Hyperphosphorylated Tau, Increased Adenylate Cyclase 5 (ADCY5) Immunoreactivity, but No Neuronal Loss in ADCY5-Dyskinesia. Movement disorders clinical practice Caitlin Latimer, MD. PhD 2020 Jan Heterozygous <i>STUB1</i> missense variants cause ataxia, cognitive decline, and STUB1 mislocalization. Neurology. Genetics Caitlin Latimer, MD. PhD 2020 Apr From Herniation to Rehabilitation: A Young Woman With Rapidly Progressive Neurological Deficits. The Neurohospitalist Caitlin Latimer, MD. PhD 2019 Oct Homozygous Mutations in CSF1R Cause a Pediatric-Onset Leukoencephalopathy and Can Result in Congenital Absence of Microglia. American journal of human genetics Caitlin Latimer, MD. PhD 2019 May 2 Resistance and resilience to Alzheimer's disease pathology are associated with reduced cortical pTau and absence of limbic-predominant age-related TDP-43 encephalopathy in a community-based cohort. Acta neuropathologica communications Caitlin Latimer, MD. PhD 2019 Jun 7 A nonhuman primate model of early Alzheimer's disease pathologic change: Implications for disease pathogenesis. Alzheimer's & dementia : the journal of the Alzheimer's Association Caitlin Latimer, MD. PhD 2019 Jan Intraoperative assessment of skull base tumors using stimulated Raman scattering microscopy. Scientific reports Caitlin Latimer, MD. PhD 2019 Dec 31 Alternative splicing in a presenilin 2 variant associated with Alzheimer disease. Annals of clinical and translational neurology Caitlin Latimer, MD. PhD 2019 Apr Ophthalmology-Based Neuropathology Risk Factors: Diabetic Retinopathy is Associated with Deep Microinfarcts in a Community-Based Autopsy Study. Journal of Alzheimer's disease : JAD Caitlin Latimer, MD. PhD 2019 Cross species application of quantitative neuropathology assays developed for clinical Alzheimer's disease samples. Pathobiology of aging & age related diseases Caitlin Latimer, MD. PhD 2019 Keratin Horn of the Palpebral Conjunctiva. Ophthalmic plastic and reconstructive surgery Caitlin Latimer, MD. PhD 2018 Jul/Aug Neutral lipid storage disease with myopathy: Further phenotypic characterization of a rare PNPLA2 variant. Neuromuscular disorders : NMD Caitlin Latimer, MD. PhD 2018 Jul First confirmed case of chronic traumatic encephalopathy in a professional bull rider. Acta neuropathologica Caitlin Latimer, MD. PhD 2018 Feb Application of the condensed protocol for the NIA-AA guidelines for the neuropathological assessment of Alzheimer's disease in an academic clinical practice. Histopathology Caitlin Latimer, MD. PhD 2018 Feb Flow cytometric evaluation of crude synaptosome preparation as a way to study synaptic alteration in neurodegenerative diseases. Neuromethods Caitlin Latimer, MD. PhD 2018 TDP-43 Neuropathologic Associations in the Nun Study and the Honolulu-Asia Aging Study. Journal of Alzheimer's disease : JAD Caitlin Latimer, MD. PhD 2018 Resistance to Alzheimer Disease Neuropathologic Changes and Apparent Cognitive Resilience in the Nun and Honolulu-Asia Aging Studies. Journal of neuropathology and experimental neurology Caitlin Latimer, MD. PhD 2017 Jun 1 Human Striatal Dopaminergic and Regional Serotonergic Synaptic Degeneration with Lewy Body Disease and Inheritance of APOE ε4. The American journal of pathology Caitlin Latimer, MD. PhD 2017 Apr Neuropathological Comparison of Adult Onset and Juvenile Huntington's Disease with Cerebellar Atrophy: A Report of a Father and Son. Journal of Huntington's disease Caitlin Latimer, MD. PhD 2017 Kristin B Linscott, MD, PhD Kristin B Linscott, MD, PhD Treatment of COVID-19 in a Patient With Maple Syrup Urine Disease. Cureus Kristin B Linscott 2022 Apr Occam's razor dulled: the occurrence of multiple genetic diagnoses. Current opinion in pediatrics Kristin B Linscott 2021 Dec 1 Agronomic and chemical performance of field-grown tobacco engineered for triterpene and methylated triterpene metabolism. Plant biotechnology journal Kristin B Linscott 2018 Jun Michael W Manning, MD, PhD Michael W Manning, MD, PhD Conventional Ultrafiltration During Elective Cardiac Surgery and Postoperative Acute Kidney Injury. Journal of cardiothoracic and vascular anesthesia Michael W Manning, MD, PhD 2021 May Planned Initiation of Venoarterial Extracorporeal Membrane Oxygenation Prior to Liver Transplantation in a Patient With Severe Portopulmonary Hypertension. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society Michael W Manning, MD, PhD 2021 May Assisted Fluid Management Software Guidance for Intraoperative Fluid Administration. Anesthesiology Michael W Manning, MD, PhD 2021 Aug 1 Enhanced Recovery After Cardiac Surgery (ERAS Cardiac) Recommendations: An Important First Step-But There Is Much Work to Be Done. Journal of cardiothoracic and vascular anesthesia Michael W Manning, MD, PhD 2020 Jan Post-Reperfusion Syndrome in Liver Transplantation-An Overview. Journal of cardiothoracic and vascular anesthesia Michael W Manning, MD, PhD 2020 Feb Perioperative Quality Initiative (POQI) consensus statement on fundamental concepts in perioperative fluid management: fluid responsiveness and venous capacitance. Perioperative medicine (London, England) Michael W Manning, MD, PhD 2020 What Does a Red Meat Allergy Have to Do With Anesthesia? Perioperative Management of Alpha-Gal Syndrome. Anesthesia and analgesia Michael W Manning, MD, PhD 2019 Nov Perioperative Anesthetic and Transfusion Management of Veno-Venous Extracorporeal Membrane Oxygenation Patients Undergoing Noncardiac Surgery: A Case Series of 21 Procedures. Journal of cardiothoracic and vascular anesthesia Michael W Manning, MD, PhD 2019 Jul Complex Role for E-Prostanoid 4 Receptors in Hypertension. Journal of the American Heart Association Michael W Manning, MD, PhD 2019 Feb 19 Impact of an enhanced recovery pathway on length of stay and complications in elective radical cystectomy: a before and after cohort study. Perioperative medicine (London, England) Michael W Manning, MD, PhD 2019 Management of Patients With Left Ventricular Assist Devices Requiring Teeth Extraction: Is Halting Anticoagulation Appropriate? Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons Michael W Manning, MD, PhD 2018 Sep Using Medical Student Quality Improvement Projects to Promote Evidence-Based Care in the Emergency Department. The western journal of emergency medicine Michael W Manning, MD, PhD 2018 Jan Defining Value-Based Care in Cardiac and Vascular Anesthesiology: The Past, Present, and Future of Perioperative Cardiovascular Care. Journal of cardiothoracic and vascular anesthesia Michael W Manning, MD, PhD 2018 Feb Enhanced Recovery After Surgery and Multimodal Strategies for Analgesia. The Surgical clinics of North America Michael W Manning, MD, PhD 2018 Dec Effect of A1C and Glucose on Postoperative Mortality in Noncardiac and Cardiac Surgeries. Diabetes care Michael W Manning, MD, PhD 2018 Apr The rising tide of opioid use and abuse: the role of the anesthesiologist. Perioperative medicine (London, England) Michael W Manning, MD, PhD 2018 Perioperative fluid and hemodynamic management within an enhanced recovery pathway. Journal of surgical oncology Michael W Manning, MD, PhD 2017 Oct Platelet Counts and Postoperative Stroke After Coronary Artery Bypass Grafting Surgery. Anesthesia and analgesia Michael W Manning, MD, PhD 2017 Oct Combining Angiotensin Converting Enzyme Inhibitors and Angiotensin Receptor Blocker for Clinical Decision-making Lacks Vision. Anesthesiology Michael W Manning, MD, PhD 2017 Oct Angiotensin Receptor Blockade Improves Cardiac Surgical Outcomes in Patients With Metabolic Syndrome. The Annals of thoracic surgery Michael W Manning, MD, PhD 2017 Jul Mathew A Nicholls, MD, PhD Mathew A Nicholls, MD, PhD The Disease-Modifying Effects of Hyaluronan in the Osteoarthritic Disease State. Clinical medicine insights. Arthritis and musculoskeletal disorders Mathew A Nicholls, MD, PhD 2017 Shane W Rau, MD, PhD Shane W Rau, MD, PhD A 12-week randomized controlled trial of twice-daily intranasal oxytocin for social cognitive deficits in people with schizophrenia. Schizophrenia research Shane W Rau, MD, PhD 2017 Jul Abdelghaffar Salous, MD, PhD Abdelghaffar Salous, MD, PhD A Novel Intraoperative Transient Variant of Immune Thrombocytopenia. Cureus Abdelghaffar Salous 2021 Jun Stakeholder Engagement Significantly Decreased Colorectal Surgical Site Infections. Surgical infections Abdelghaffar Salous 2021 Apr A significant proportion of venous thromboembolism events in general surgical patients occurs after discharge: analysis of the ACS-NSQIP Essentials database. Perioperative medicine (London, England) Abdelghaffar Salous 2019 Endothelial alterations in a canine model of immune thrombocytopenia. Platelets Abdelghaffar Salous 2019 Scott Silva, MD, PhD Scott Silva, MD, PhD Verrucous carcinoma of the vulva: Patterns of care and treatment outcomes. Cancer reports (Hoboken, N.J.) Scott Silva 2022 Jan 24 Trends in Incidence and Mortality Rates of Uterine Cancer in Kentucky. Southern medical journal Scott Silva 2021 Oct Role of adjuvant chemotherapy in patients with FIGO stage IB grade 3 endometrial endometrioid adenocarcinoma treated with surgery and post-operative radiotherapy. International journal of gynecological cancer : official journal of the International Gynecological Cancer Society Scott Silva 2021 May Vaginal cuff brachytherapy: do we need to treat to more than a two-centimeter active length? Journal of contemporary brachytherapy Scott Silva 2021 Jun The impact of brachytherapy boost and radiotherapy treatment duration on survival in patients with vaginal cancer treated with definitive chemoradiation. Brachytherapy Scott Silva 2021 Jan-Feb Patterns of care and outcomes of radiotherapy or hormone therapy in patients with medically inoperable endometrial adenocarcinoma. Gynecologic oncology Scott Silva 2021 Dec Cervical cancer incidence and mortality rates in Kentucky. Gynecologic oncology Scott Silva 2020 Aug National Cancer Database Analysis of the effect of brachytherapy on overall survival in patients with base of tongue cancer. Head & neck Scott Silva 2019 May Integrating a 92-Gene Expression Analysis for the Management of Neuroendocrine Tumors of Unknown Primary Asian Pacific journal of cancer prevention : APJCP Scott Silva 2019 Jan 25 Oligometastatic Disease State Is Associated with Improved Local Control in Patients Undergoing Three or Five Fraction Spine Stereotactic Body Radiotherapy. World neurosurgery Scott Silva 2019 Feb Does adjuvant concurrent or sequential chemotherapy increase the radiation-related toxicity of vaginal brachytherapy for endometrial cancer patients? Brachytherapy Scott Silva 2018 Nov - D Clinical Application of a Hybrid RapidArc Radiotherapy Technique for Locally Advanced Lung Cancer. Technology in cancer research & treatment Scott Silva 2017 Apr Christopher Simmons, MD, PhD Christopher Simmons, MD, PhD KIL1 terminates fertility in maize by controlling silk senescence. The Plant cell Christopher Simmons 2022 May 24 Structural Basis for Blocked Excited State Proton Transfer in a Fluorescent, Photoacidic Non-Canonical Amino Acid-Containing Antibody Fragment. Journal of molecular biology Christopher Simmons 2022 Apr 30 Successes and insights of an industry biotech program to enhance maize agronomic traits. Plant science : an international journal of experimental plant biology Christopher Simmons 2021 Jun Structure-guided identification of a peptide for bio-enabled gold nanoparticle synthesis. Biotechnology and bioengineering Christopher Simmons 2021 Dec Structural Origins of Altered Spectroscopic Properties upon Ligand Binding in Proteins Containing a Fluorescent Noncanonical Amino Acid. Biochemistry Christopher Simmons 2021 Aug 31 Structural Insights into How Protein Environments Tune the Spectroscopic Properties of a Noncanonical Amino Acid Fluorophore. Biochemistry Christopher Simmons 2020 Sep 22 Tetragonal crystal form of the cyanobacterial bicarbonate-transporter regulator SbtB from Synechocystis sp. PCC 6803. Acta crystallographica. Section F, Structural biology communications Christopher Simmons 2020 Sep 1 A Self-Assembled Rhombohedral DNA Crystal Scaffold with Tunable Cavity Sizes and High-Resolution Structural Detail. Angewandte Chemie (International ed. in English) Christopher Simmons 2020 Oct 12 Maize BIG GRAIN1 homolog overexpression increases maize grain yield. Plant biotechnology journal Christopher Simmons 2020 Nov Enhanced Photocatalytic Hydrogen Production by Hybrid Streptavidin-Diiron Catalysts. Chemistry (Weinheim an der Bergstrasse, Germany) Christopher Simmons 2020 May 15 Evidence for Limited Early Spread of COVID-19 Within the United States, January-February 2020. MMWR. Morbidity and mortality weekly report Christopher Simmons 2020 Jun 5 Correction to Tunable Nanoscale Cages from Self-Assembling DNA and Protein Building Blocks. ACS nano Christopher Simmons 2020 Jun 23 Hierarchical Assembly of Nucleic Acid/Coiled-Coil Peptide Nanostructures. Journal of the American Chemical Society Christopher Simmons 2020 Jan 22 Tunable Nanoscale Cages from Self-Assembling DNA and Protein Building Blocks. ACS nano Christopher Simmons 2019 Mar 26 Redox Engineering of Cytochrome c using DNA Nanostructure-Based Charged Encapsulation and Spatial Control. ACS applied materials & interfaces Christopher Simmons 2019 Apr 17 Self-Assembly of a 3D DNA Crystal Structure with Rationally Designed Six-Fold Symmetry. Angewandte Chemie (International ed. in English) Christopher Simmons 2018 Sep 17 Tuning the Cavity Size and Chirality of Self-Assembling 3D DNA Crystals. Journal of the American Chemical Society Christopher Simmons 2017 Aug 16 Gregory J Wehner, MD, PhD Gregory J Wehner, MD, PhD Deep-learning-assisted analysis of echocardiographic videos improves predictions of all-cause mortality. Nature biomedical engineering Gregory J Wehner 2021 Jun Routinely reported ejection fraction and mortality in clinical practice: where does the nadir of risk lie? European heart journal Gregory J Wehner 2020 Mar 21 Predicting Survival From Large Echocardiography and Electronic Health Record Datasets: Optimization With Machine Learning. JACC. Cardiovascular imaging Gregory J Wehner 2019 Apr Comparison of left ventricular strains and torsion derived from feature tracking and DENSE CMR. Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance Gregory J Wehner 2018 Sep 13 Predicting deterioration of ventricular function in patients with repaired tetralogy of Fallot using machine learning. European heart journal. Cardiovascular Imaging Gregory J Wehner 2018 Jul 1 Typical readout durations in spiral cine DENSE yield blurred images and underestimate cardiac strains at both 3.0 T and 1.5 T. Magnetic resonance imaging Gregory J Wehner 2018 Dec Ambulatory systolic blood pressure and obesity are independently associated with left ventricular hypertrophic remodeling in children. Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance Gregory J Wehner 2017 Nov 9 Right Ventricular Strain, Torsion, and Dyssynchrony in Healthy Subjects Using 3D Spiral Cine DENSE Magnetic Resonance Imaging. IEEE transactions on medical imaging Gregory J Wehner 2017 May Using a respiratory navigator significantly reduces variability when quantifying left ventricular torsion with cardiovascular magnetic resonance. Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance Gregory J Wehner 2017 Mar 1 Optimal configuration of respiratory navigator gating for the quantification of left ventricular strain using spiral cine displacement encoding with stimulated echoes (DENSE) MRI. Journal of magnetic resonance imaging : JMRI Gregory J Wehner 2017 Mar Impaired right ventricular contractile function in childhood obesity and its association with right and left ventricular changes: a cine DENSE cardiac magnetic resonance study. Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance Gregory J Wehner 2017 Jun 28 Association between left ventricular mechanics and diffuse myocardial fibrosis in patients with repaired Tetralogy of Fallot: a cross-sectional study. Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance Gregory J Wehner 2017 Dec 11 Regional quantification of myocardial mechanics in rat using 3D cine DENSE cardiovascular magnetic resonance. NMR in biomedicine Gregory J Wehner 2017 Aug Mark A Wurth, MD, PhD Mark A Wurth, MD, PhD Clinical Effectiveness of Elexacaftor/Tezacaftor/Ivacaftor in People with Cystic Fibrosis: A Clinical Trial. American journal of respiratory and critical care medicine Mark A Wurth, MD, PhD 2022 Mar 1 Opportunities to support emotional health in school-age children with food allergy. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology Mark A Wurth, MD, PhD 2021 Jun CFTR modulator drug desensitization: Preserving the hope of long term improvement. Pediatric pulmonology Mark A Wurth, MD, PhD 2021 Aug Incidence of nephrotoxicity with prolonged aminoglycoside exposure in patients with cystic fibrosis. Pediatric pulmonology Mark A Wurth, MD, PhD 2020 Dec Ivacaftor drug desensitization. Pediatric pulmonology Mark A Wurth, MD, PhD 2019 Jun Human IgE mAbs define variability in commercial Aspergillus extract allergen composition. JCI insight Mark A Wurth, MD, PhD 2018 Oct 18 Risk Factors Associated with Asthma Development and Control in Children. Mouse Infestation, Antipyretics, Respiratory Viruses, and Allergic Sensitization. American journal of respiratory and critical care medicine Mark A Wurth, MD, PhD 2017 Dec 15 Kristine S Ziemba, MD, PhD Kristine S Ziemba, MD, PhD Partial Reconstruction of the Nigrostriatal Circuit along a Preformed Molecular Guidance Pathway. Molecular therapy. Methods & clinical development Kristine S Ziemba, MD, PhD 2019 Sep 13
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