Our Research We bring together experts from across the University of Kentucky to understand and fight infectious diseases.

Microbial Pathogenesis and Host Defense

Researchers within the domain of microbial pathogenesis study the intricate process through which microorganisms like bacteria, viruses, parasites and fungi cause diseases. We explore the multifaceted interactions between pathogens and their hosts, unraveling the mechanisms of invasion, colonization, immune evasion and host defense. By understanding how pathogens manipulate host cells and systems, we aim to develop innovative strategies for disease prevention and treatment. 

Vaccines, Therapeutics, and Antimicrobial Resistance

Researchers in this field explore innovative approaches to developing effective immunization strategies against infectious diseases, leveraging cutting-edge technologies and immunological insights. In therapeutics, we investigate novel treatments for wide range of microbial infections, aiming to combat emerging pathogens and address the challenges of antimicrobial resistance. Through our research, we strive to combat the global threat of infectious diseases by developing novel vaccines and safeguarding antimicrobial efficacy.

Emerging Zoonotic Diseases and Animal Health

Our research in animal health aims at enhancing the well-being of animals. We explore preventative measures, diagnostics, and treatments to address infectious diseases, ensuring the health and productivity of livestock, pets, and wildlife. Our efforts extend to promoting sustainable practices in animal husbandry and veterinary medicine, emphasizing welfare considerations and the responsible use of antimicrobials. The other component of our animal health research is to develop novel tools for rapid detection and characterization of zoonotic pathogens emerging at the animal-human interface and turn the discovery to product development that can protect humans and animals. 

Engineering Systems and Diagnostics

The field of engineering systems plays a crucial role in understanding and combating infectious diseases ranging from developing advanced diagnostic tools to designing efficient healthcare infrastructure. Engineers contribute by creating innovative technologies for rapid detection, monitoring, and treatment of infections. Innovative ventilation systems are designed to mitigate airborne transmission in healthcare facilities and public spaces. Supply chains for vaccines and medical supplies are optimized, ensuring timely distribution during outbreaks. Pioneering data analytics and modeling approaches to predict disease spread and assess intervention strategies. Ultimately, engineering systems empower us to address infectious diseases with precision and efficacy.

Public Health and Community Engagement

In the realm of infectious diseases, epidemiologic studies coupled with robust public health initiatives and community engagement are paramount for effective prevention and control. Collaboration between health authorities, communities, and stakeholders fosters a proactive approach, enhancing disease surveillance, early detection, and response capabilities. Engaging communities cultivates trust, empowers individuals with accurate information, and promotes adherence to preventative measures like vaccination and hygiene practices. Moreover, community involvement enables tailored interventions, considering local contexts and addressing disparities in healthcare access.