Congratulations to Cassandra Reiling for passing her Ph.D. defense in Toxicology on Friday, 11/15/2013!
Congratulations to Wei Zhang on receiving First place at the 16th Annual Gill Heart Institute Cardiovascular Research Day!
Congratulations to Hedy Chawsheen and Murli Mishra for passing their qualifying exams!
The "Triple Crown" is a term reserved for the greatest accomplishment in thoroughbred racing -- winning the Kentucky Derby, Preakness Stakes and Belmont Stakes.
Transporters function in cellular influx and efflux to maintain homeostasis for normal cellular and tissue physiology. Therefore, they play an important role in eliminating xenobiotics from the body.
Cancer research at the Department of Toxicology and Cancer Biology involves multiple laboratories with various focus areas. They include chemical carcinogenesis, metal carcinogenesis, tumor suppressor genes, gene regulation during carcinogenesis, redox-mediated mechanisms of tumor suppression, reactive oxygen species and cancer, cell signaling in cancer biology, environmental risk factors in cancer, and cancer prevention.
Wei has been awarded a predoctoral fellowship from American Heart Association 07/01/13 – 6/30/14. Her project title is: The Role of Mrp1 in Protecting against Doxorubicin - induced Cardiotoxicity.
It appears tiny and inconsequential enough, but the "super mouse" — created by researchers at the University of Kentucky Markey Cancer Center some six years ago — has spawned plenty of new research into preventing and/or treating many types of cancer. Back in 2007, cancer researcher Vivek Rangnekar and his team announced that they discovered a gene — known as Par-4 —that specifically kills cancer cells without killing normal cells.

As a native Kentuckian, the University of Kentucky Markey Cancer Center's Dr. Susanne Arnold understands many of the health issues our state faces — and focusing on the problems that hit hardest close to home has kept her motivated in her work.

"I got into research in Appalachia because I'm an eighth-generation Kentuckian, and my father, who was also a doctor and researcher, was a seventh-generation Kentuckian," Arnold said. "I learned a very valuable lesson from him — that we can't make progress in the treatment of diseases without being invested in the research that we do."