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The University of Kentucky College of Medicine invites applications and nominations for the position of chair to lead the highly ranked department of molecular and cellular biochemistry.

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Congratulations to Professor Becky Dutch of the Department of Molecular & Cellular Biochemistry on her election as a Fellow of the American Academy of Microbiology!

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The Department had seven publications listed in PubMed for the month of January 2022.

1: Yin H, Jing B, Xu D, Guo W, Sun B, Zhang J, Liao Y, Song H, Wang T, Liu S, Kuang Y, Hu M, Li K, Zhang S, Zhang H, Xu J, Li X, Du J, Wu Y, Wu Y, Wang Q, Yao F, Chin YE, Zhou BP, Deng J. Identification of Active Bronchioalveolar Stem Cells as the Cell-of-Origin in Lung Adenocarcinoma. Cancer Res. 2022 Jan 19:canres.2445.2021. doi: 10.1158/0008-5472.CAN-21-2445. Epub ahead of print. PMID: 35045987.

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LEXINGTON, Ky. (Feb. 2, 2022) – A team of researchers from the University of Kentucky’s Sanders-Brown Center on Aging (SBCoA) is working to identify new proteins that are destructive to the brain. They know that about 25% of individuals, and 50% of individuals with Alzheimer disease, have the genetic mutation APOE ε4 allele — a known risk factor for the disease.

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LEXINGTON, Ky. (Jan. 27, 2022) — The Kentucky Network for Innovation and Commercialization (KYNETIC) has opened its Spring 2022 Cycle 5 round of early-stage commercialization grants. 

KYNETIC is a National Institutes of Health (NIH) funded Research Evaluation and Commercialization Hub (REACH) and part of the national NIH Proof-of-Concept Network. 

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LEXINGTON, Ky. (Jan. 20, 2022) — As the University of Kentucky begins another semester during the COVID-19 pandemic, experts from across campus are being called upon to answer the many questions being asked by those on campus and in our communities. 

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LEXINGTON, Ky. (Jan. 13, 2022) — The University of Kentucky is participating in a nationwide study that seeks to understand why some people have prolonged symptoms (long COVID) or develop new or returning symptoms after an acute bout of SARS-CoV-2 infection.

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The Department had eight publications listed in PubMed for the month of December 2021. The contributions of our graduate students are highlighted with bold text.

The Department ended the year with a total of 83 publications!

1: Ostrakhovitch EA, Song ES, Macedo JKA, Gentry MS, Quintero JE, van Horne C, Yamasaki TR. Analysis of circulating metabolites to differentiate Parkinson's disease and essential tremor. Neurosci Lett. 2021 Dec 28:136428. doi: 10.1016/j.neulet.2021.136428. Epub ahead of print. PMID: 34971771.

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LEXINGTON, Ky. (Dec. 16, 2021) — Using new methodology, University of Kentucky researchers have mapped the variations in sugar chains attached to brain proteins from deceased healthy individuals or individuals with Alzheimer’s disease.

Thus far, no effective treatments for Alzheimer’s disease (AD) are available. New approaches to preventing the progression of this devastating neurological disease are desperately needed.

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The Department had eight publications listed in PubMed for the month of November 2021. The contributions of our graduate students are highlighted with bold text.

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The Department had seven publications listed in PubMed for the month of October 2021. The contributions of our graduate students are highlighted with bold text.

1: Conroy LR, Stanback AE, Young LEA, Clarke HA, Austin GL, Liu J, Allison DB, Sun RC. <i>In Situ</i> Analysis of N-Linked Glycans as Potential Biomarkers of Clinical Course in Human Prostate Cancer. Mol Cancer Res. 2021 Oct;19(10):1727-1738. doi: 10.1158/1541-7786.MCR-20-0967. Epub 2021 Jun 15. PMID: 34131069; PMCID: PMC8492534.

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The University of Kentucky College of Medicine has received the 2021 Health Professions Higher Education Excellence in Diversity (HEED) Award from INSIGHT Into Diversity magazine, the oldest and largest diversity-focused publication in higher education.

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The Department had eight publications listed in PubMed for the month of September 2021. The contributions of our graduate students are highlighted with bold text.

1: Wilson P, Abdelmoti L, Norcross R, Jang ER, Palayam M, Galperin E. The role of USP7 in the Shoc2 - ERK1/2 signaling axis and Noonan-like syndrome with loose anagen hair (NSLAH). J Cell Sci. 2021 Sep 23:jcs.258922. doi: 10.1242/jcs.258922. Epub ahead of print. PMID: 34553755.

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LEXINGTON, Ky. (Sept. 9, 2021) — On Aug. 24, 2021, University of Kentucky senior Zakeya Baker sat down with health experts Becky Dutch, Ph.D, and Alice Thornton, M.D., to ask questions about COVID-19, vaccines and UK’s response to the virus. Dutch and Thornton addressed concerns common to students as well as many individuals across the globe.

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The Department had seven publications listed in PubMed for the month of August 2021.

1: Hammill JT, Sviripa VM, Kril LM, Ortiz D, Fargo CM, Kim HS, Chen Y, Rector J, Rice AL, Domagalska MA, Begley KL, Liu C, Rangnekar VM, Dujardin JC, Watt DS, Landfear SM, Guy RK. Amino-Substituted 3-Aryl- and 3-Heteroarylquinolines as Potential Antileishmanial Agents. J Med Chem. 2021 Aug 26;64(16):12152-12162. doi: 10.1021/acs.jmedchem.1c00813. Epub 2021 Aug 6. PMID: 34355566; PMCID: PMC8404201.

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LEXINGTON, Ky. (Aug. 31, 2021) — University of Kentucky Office of Nationally Competitive Awards has announced biology and Lewis Honors College student Kayli Bolton is one of 2021’s 60 recipients to be awarded a scholarship of up to $15,000 from the Astronaut Scholarship Foundation (ASF).

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The University of Kentucky College of Medicine is pleased to announce its selection of Tianyan Gao, PhD, as acting chair of the department of molecular and cellular biochemistry.

Dr. Gao has dedicated more than a decade to the UK College of Medicine as an educator and researcher, mentoring several students, post-docs, and residents over the years while obtaining substantial funding from the National Institutes of Health and other major organizations.

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The Department had ten publications listed in PubMed for the month of July 2021.

1: Smith CN, Blackburn JS. PRL-3 promotes a positive feedback loop between STAT1/2-induced gene expression and glycolysis in multiple myeloma. FEBS J. 2021 Jul 29. doi: 10.1111/febs.16120. Epub ahead of print. PMID: 34327809.

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LEXINGTON, Ky. (July 19, 2021) — As the SARS-CoV-2 delta variant continues to spread across the United States and hospitals’ COVID-positive intake numbers climb again, many questions remain around both vaccine effectiveness and vaccination rates, and what these numbers could mean moving into the fall.

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The Department had twelve publications listed in PubMed for the month of June 2021.

1: Jin H, Moseley HNB. Hierarchical Harmonization of Atom-Resolved Metabolic Reactions across Metabolic Databases. Metabolites. 2021 Jun 30;11(7):431. doi: 10.3390/metabo11070431. PMID: 34209357.