The Department had ten publications listed in PubMed for the months of March and April 2022.

1: Gentry MS, Markussen KH, Donohue KJ. Two Diseases-One Preclinical Treatment Targeting Glycogen Synthesis. Neurotherapeutics. 2022 Apr 22. doi: 10.1007/s13311-022-01240-9. Epub ahead of print. PMID: 35460010.

2: Shon H, Matveeva EA, Jull EC, Hu Y, Coupet TA, Lee YS. Evidence Supporting Substrate Channeling between Domains of Human PAICS: A Time-Course Analysis of 13C-Bicarbonate Incorporation. Biochemistry. 2022 Apr 5;61(7):575-582. doi: 10.1021/acs.biochem.1c00803. Epub 2022 Mar 14. PMID: 35285625; PMCID: PMC8988938.

3: Xiong X, Hasani S, Young LEA, Rivas DR, Skaggs AT, Martinez R, Wang C, Weiss HL, Gentry MS, Sun RC, Gao T. Activation of Drp1 promotes fatty acids-induced metabolic reprograming to potentiate Wnt signaling in colon cancer. Cell Death Differ. 2022 Mar 24. doi: 10.1038/s41418-022-00974-5. Epub ahead of print. PMID: 35332310.

4: Creeden JF, Kipp ZA, Xu M, Flight RM, Moseley HNB, Martinez GJ, Lee WH, Alganem K, Imami AS, McMullen MR, Roychowdhury S, Nawabi AM, Hipp JA, Softic S, Weinman SA, McCullumsmith R, Nagy LE, Hinds TD Jr. Hepatic Kinome Atlas: An In-Depth Identification of Kinase Pathways in Liver Fibrosis of Humans and Rodents. Hepatology. 2022 Mar 21. doi: 10.1002/hep.32467. Epub ahead of print. PMID: 35313030.

5: Séguin O, Mai LT, Acevedo Ospina H, Guay-Vincent MM, Whiteheart SW, Stäger S, Descoteaux A. VAMP3 and VAMP8 Regulate the Development and Functionality of Parasitophorous Vacuoles Housing Leishmania amazonensis. Infect Immun. 2022 Mar 17;90(3):e0018321. doi: 10.1128/IAI.00183-21. Epub 2022 Feb 7. PMID: 35130453; PMCID: PMC8929380.

6: Lee JH, Mosher EP, Lee YS, Bumpus NN, Berger JM. Control of topoisomerase II activity and chemotherapeutic inhibition by TCA cycle metabolites. Cell Chem Biol. 2022 Mar 17;29(3):476-489.e6. doi: 10.1016/j.chembiol.2021.08.014. Epub 2021 Sep 15. PMID: 34529934; PMCID: PMC8913808.

7: Yin H, Jing B, Xu D, Guo W, Sun B, Zhang J, Liao Y, Song H, Wang T, Liu S, Kuang Y, Hu M, Li K, Zhang S, Zhang H, Xu J, Li X, Du J, Wu Y, Wu Y, Wang Q, Yao F, Chin YE, Zhou BP, Deng J. Identification of Active Bronchioalveolar Stem Cells as the Cell of Origin in Lung Adenocarcinoma. Cancer Res. 2022 Mar 15;82(6):1025-1037. doi: 10.1158/0008-5472.CAN-21-2445. PMID: 35045987.

8: Kontaridis MI, Roberts AE, Schill L, Schoyer L, Stronach B, Andelfinger G, Aoki Y, Axelrad ME, Bakker A, Bennett AM, Broniscer A, Castel P, Chang CA, Cyganek L, Das TK, den Hertog J, Galperin E, Garg S, Gelb BD, Gordon K, Green T, Gripp KW, Itkin M, Kiuru M, Korf BR, Livingstone JR, López-Juárez A, Magoulas PL, Mansour S, Milner T, Parker E, Pierpont EI, Plouffe K, Rauen KA, Shankar SP, Smith SB, Stevenson DA, Tartaglia M, Van R, Wagner ME, Ware SM, Zenker M. The seventh international RASopathies symposium: Pathways to a cure-expanding knowledge, enhancing research, and therapeutic discovery. Am J Med Genet A. 2022 Mar 9. doi: 10.1002/ajmg.a.62716. Epub ahead of print. PMID: 35266292.

9: Jia J, Jiang J. Regulation of Smoothened Trafficking and Abundance in Hedgehog Signaling. Front Cell Dev Biol. 2022 Mar 7;10:847844. doi: 10.3389/fcell.2022.847844. PMID: 35321245; PMCID: PMC8936432.

10: Gal J, Katsumata Y, Zhu H, Srinivasan S, Chen J, Johnson LA, Wang WX, Golden LR, Wilcock DM, Jicha GA, Cykowski MD, Nelson PT. Apolipoprotein E Proteinopathy Is a Major Dementia-Associated Pathologic Biomarker in Individuals with or without the APOE Epsilon 4 Allele. Am J Pathol. 2022 Mar;192(3):564-578. doi: 10.1016/j.ajpath.2021.11.013. Epub 2021 Dec 24. PMID: 34954207; PMCID: PMC8895423.

IMG_2611.jpeg