Our full departmental research profile can be found on Scholars@UK.
A cautionary tale about properly vetting datasets used in supervised learning predicting metabolic pathway involvement
Huckvale, E. D. & Moseley, H. N. B., May 2024, In: PLoS ONE. 19, 5 MAY, e0299583.Research output: Contribution to journal › Article › peer-review
A dynamic model of inorganic arsenic-induced carcinogenesis reveals an epigenetic mechanism for epithelial–mesenchymal plasticity.
Rea, M., Kimmerer, G., Mittendorf, S., Xiong, X., Green, M., Chandler, D., Saintilnord, W., Blackburn, J., Gao, T. & Fondufe-Mittendorf, Y. N., Apr 15 2024, In: Environmental Pollution. 347, 123586.Research output: Contribution to journal › Article › peer-review
Aldh2 deficiency plays a dual role in lung tumorigenesis and tumor progression
Zhang, H., Sun, X., Li, Z., Liu, T., Zhang, F., Meng, X., Li, K., Xu, J., He, W., Jing, B., Wang, T., Ni, N., Sun, B., Yao, F., Wu, Y., Wang, Q., Du, J., Chin, E. Y., Zhou, B. P., Jiang, P., & 2 others , May 2024, In: Genes and Diseases. 11, 3, 100999.Research output: Contribution to journal › Article › peer-review
A Novel Protozoa Parasite-Derived Protein Adjuvant Is Effective in Immunization with Cancer Cells to Activate the Cancer-Specific Protective Immunity and Inhibit the Cancer Growth in a Murine Model of Colorectal Cancer
Mani, R., Martin, C. G., Balu, K. E., Wang, Q., Rychahou, P., Izumi, T., Evers, B. M. & Suzuki, Y., Jan 2024, In: Cells. 13, 2, 111.Research output: Contribution to journal › Article › peer-review
Creating an Integrated Coaching Culture in Higher Education
Bradley, J. A., Tuck, M. E., Reynolds, M. A. & Bradley, L. H., 2024, In: Journal of appreciative education. 11, p. 15-24 10 p.Research output: Contribution to journal › Article › peer-review
Disorder regulates homeostasis of extracytoplasmic proteins in streptococci
Rahman, M. M., Zamakhaeva, S., Rush, J. S., Chaton, C. T., Kenner, C. W., Hla, Y. M., Tsui, H-C. T., Winkler, M. E., Korotkov, K. V. & Korotkova, N., May 8 2024, In: bioRxiv.Research output: Contribution to journal › Article
EcoHIV-Infected Mice Show No Signs of Platelet Activation
Alfar, H. R., Nthenge-Ngumbau, D. N., Saatman, K. E. & Whiteheart, S. W., Jan 2024, In: Viruses. 16, 1, 55.Research output: Contribution to journal › Article › peer-review
Everolimus alleviates CD4+ T cell inflammation by regulating autophagy and cellular redox homeostasis
Rockhold, J. D., Marszalkowski, H., Sannella, M., Gibney, K., Murphy, L., Zukowski, E., Kalantar, G. H., SantaCruz-Calvo, S., Hart, S. N., Kuhn, M. K., Yu, J., Stefanik, O., Chase, G., Proctor, E. A., Hasturk, H., Nikolajczyk, B. S. & Bharath, L. P., 2024, (Accepted/In press) In: GeroScience.Research output: Contribution to journal › Article › peer-review
Examining Phosphatases Through Immunofluorescent Microscopy
Smith, C. N. & Blackburn, J. S., 2024, Methods in Molecular Biology. p. 111-122 12 p. (Methods in Molecular Biology; vol. 2743).Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
Fasting and Glucose Metabolism Differentially Impact Peripheral Inflammation in Human Type 2 Diabetes
Kalantar, G. H., Saraswat, S., SantaCruz-Calvo, S., Gholamrezaeinejad, F., Javidan, A., Agrawal, M., Liu, R., Kern, P., Zhang, X. & Nikolajczyk, B. S., May 7 2024, In: Nutrients. 16, 10Research output: Contribution to journal › Article › peer-review
Gestational diabetes augments group B Streptococcus infection by disrupting maternal immunity and the vaginal microbiota
Mercado-Evans, V., Mejia, M. E., Zulk, J. J., Ottinger, S., Hameed, Z. A., Serchejian, C., Marunde, M. G., Robertson, C. M., Ballard, M. B., Ruano, S. H., Korotkova, N., Flores, A. R., Pennington, K. A. & Patras, K. A., Dec 2024, In: Nature Communications. 15, 1Research output: Contribution to journal › Article › peer-review
InChI isotopologue and isotopomer specifications
Moseley, H. N. B., Rocca-Serra, P., Salek, R. M., Arita, M. & Schymanski, E. L., Dec 2024, In: Journal of Cheminformatics. 16, 1, 54.Research output: Contribution to journal › Article › peer-review
Influence of FTDP-17 mutants on circular tau RNAs
Margvelani, G., Welden, J. R., Maquera, A. A., Van Eyk, J. E., Murray, C., Miranda Sardon, S. C. & Stamm, S., Apr 2024, In: Biochimica et Biophysica Acta - Molecular Basis of Disease. 1870, 4, 167036.Research output: Contribution to journal › Article › peer-review
Inhibition of ribonucleotide reductase subunit M2 enhances the radiosensitivity of metastatic pancreatic neuroendocrine tumor
Chow, Z., Johnson, J., Chauhan, A., Jeong, J. C., Castle, J. T., Izumi, T., Weiss, H., Townsend, C. M., Schrader, J., Anthony, L., Yang, E. S., Evers, B. M. & Rychahou, P., Aug 1 2024, In: Cancer Letters. 596, 216993.Research output: Contribution to journal › Article › peer-review
Neurotensin accelerates atherosclerosis and increases circulating levels of short-chain and saturated triglycerides
Li, J., Yang, L., Song, J., Yan, B., Morris, A. J., Moseley, H., Flight, R., Wang, C., Liu, J., Weiss, H. L., Morris, E. F., Abdelhamid, I., Gerl, M. J., Melander, O., Smyth, S. & Evers, B. M., May 2024, In: Atherosclerosis. 392, 117479.Research output: Contribution to journal › Article › peer-review
Overexpression of Fatty Acid Synthase Upregulates Glutamine–Fructose-6-Phosphate Transaminase 1 and O-Linked N-Acetylglucosamine Transferase to Increase O-GlcNAc Protein Glycosylation and Promote Colorectal Cancer Growth
Drury, J., Geisen, M. E., Tessmann, J. W., Rychahou, P. G., Kelson, C. O., He, D., Wang, C., Evers, B. M. & Zaytseva, Y. Y., May 2024, In: International Journal of Molecular Sciences. 25, 9, 4883.Research output: Contribution to journal › Article › peer-review
Perfluorooctanesulfonic acid exposure leads to downregulation of 3-hydroxy-3-methylglutaryl-CoA synthase 2 expression and upregulation of markers associated with intestinal carcinogenesis in mouse intestinal tissues
Tessmann, J. W., Deng, P., Durham, J., Li, C., Banerjee, M., Wang, Q., Goettl, R. A., He, D., Wang, C., Lee, E. Y., Evers, B. M., Hennig, B. & Zaytseva, Y. Y., Jul 2024, In: Chemosphere. 359, 142332.Research output: Contribution to journal › Article › peer-review
Predicting the Pathway Involvement of Metabolites Based on Combined Metabolite and Pathway Features
Huckvale, E. D. & Moseley, H. N. B., May 2024, In: Metabolites. 14, 5, 266.Research output: Contribution to journal › Article › peer-review
Sex and Sleep Disruption as Contributing Factors in Alzheimer's Disease
Johnson, C. E., Duncan, M. J. & Murphy, M. P., 2024, In: Advances in Alzheimer's Disease. 10, p. 321-364 44 p.Research output: Contribution to journal › Review article › peer-review
Sex and Sleep Disruption as Contributing Factors in Alzheimer's Disease
Johnson, C. E., Duncan, M. J. & Paul Murphy, M., Jan 2 2024, In: Journal of Alzheimer's Disease. 97, 1, p. 31-74 44 p.Research output: Contribution to journal › Review article › peer-review
Structure, dynamics, and redox reactivity of an all-purpose flavodoxin
Khan, S., Ansari, A., Brachi, M., Das, D., El Housseini, W., Minteer, S. & Miller, A. F., Apr 2024, In: Journal of Biological Chemistry. 300, 4, 107122.Research output: Contribution to journal › Article › peer-review
Structure and mechanism of biosynthesis of Streptococcus mutans cell wall polysaccharide.
Rush, J. S., Zamakhaeva, S., Murner, N. R., Deng, P., Morris, A. J., Kenner, C. W., Black, I., Heiss, C., Azadi, P., Korotkov, K. V., Widmalm, G. & Korotkova, N., May 9 2024, In: bioRxiv.Research output: Contribution to journal › Article
T cells in obesity-associated inflammation: The devil is in the details
Valentine, Y. & Nikolajczyk, B. S., 2024, (Accepted/In press) In: Immunological Reviews.Research output: Contribution to journal › Review article › peer-review
The amyloid-β peptide: Guilty as charged?
Murphy, M. P., Buzinova, V. A. & Johnson, C. E., Feb 2024, In: Biochimica et Biophysica Acta - Molecular Basis of Disease. 1870, 2, 166945.Research output: Contribution to journal › Article › peer-review
The association of GNB5 with Alzheimer disease revealed by genomic analysis restricted to variants impacting gene function
Zhang, J., Pandey, M., Awe, A., Lue, N., Kittock, C., Fikse, E., Degner, K., Staples, J., Mokhasi, N., Chen, W., Yang, Y., Adikaram, P., Jacob, N., Greenfest-Allen, E., Thomas, R., Bomeny, L., Zhang, Y., Petros, T. J., Wang, X., Li, Y., & 1 others , Mar 7 2024, In: American Journal of Human Genetics. 111, 3, p. 473-486 14 p.Research output: Contribution to journal › Article › peer-review
Zebrafish drug screening identifies Erlotinib as an inhibitor of Wnt/β-catenin signaling and self-renewal in T-cell acute lymphoblastic leukemia
Al-Hamaly, M. A., Cox, A. H., Haney, M. G., Zhang, W., Arvin, E. C., Sampathi, S., Wimsett, M., Liu, C. & Blackburn, J. S., Jan 2024, In: Biomedicine and Pharmacotherapy. 170, 116013.Research output: Contribution to journal › Article › peer-review
ABL1/2 and DDR1 Drive MEKi Resistance in NRAS-Mutant Melanomas by Stabilizing RAF/MYC/ETS1 and Promoting RAF Homodimerization
Lyon, A., Tripathi, R., Meeks, C., He, D., Wu, Y., Liu, J., Wang, C., Chen, J., Zhu, H., Mukherjee, S., Ganguly, S. & Plattner, R., Feb 2023, In: Cancers. 15, 3, 954.Research output: Contribution to journal › Article › peer-review
A blunted TH17 cytokine signature in women with mild cognitive impairment: insights from inflammatory profiling of a community-based cohort of older adults
Bachstetter, A. D., Lutshumba, J., Winford, E., Abner, E. L., Martin, B. J., Harp, J. P., Van Eldik, L. J., Schmitt, F. A., Wilcock, D. M., Stowe, A. M., Jicha, G. A. & Nikolajczyk, B. S., 2023, In: Brain Communications. 5, 5, fcad259.Research output: Contribution to journal › Article › peer-review
A Case for Accelerating Standards to Achieve the FAIR Principles of Environmental Health Research Experimental Data
Nault, R., Cave, M. C., Ludewig, G., Moseley, H. N. B., Pennell, K. G. & Zacharewski, T., Jun 2023, In: Environmental Health Perspectives. 131, 6, 065001.Research output: Contribution to journal › Article › peer-review
Activated protein C, protein S, and tissue factor pathway inhibitor cooperate to inhibit thrombin activation
Li, X., Song, X., Mahmood, D. F. D., Sim, M. M. S., Bidarian, S. J. & Wood, J. P., Oct 2023, In: Thrombosis Research. 230, p. 84-93 10 p.Research output: Contribution to journal › Article › peer-review
Alzheimer’s disease pathogenetic progression is associated with changes in regulated retained introns and editing of circular RNAs
Arizaca Maquera, K. A., Welden, J. R., Margvelani, G., Miranda Sardón, S. C., Hart, S., Robil, N., Hernandez, A. G., de la Grange, P., Nelson, P. T. & Stamm, S., 2023, In: Frontiers in Molecular Neuroscience. 16, 1141079.Research output: Contribution to journal › Article › peer-review
A monoadduct generating Ru(ii) complex induces ribosome biogenesis stress and is a molecular mimic of phenanthriplatin
Mitchell, R. J., Kriger, S. M., Fenton, A. D., Havrylyuk, D., Pandeya, A., Sun, Y., Smith, T., DeRouchey, J. E., Unrine, J. M., Oza, V., Blackburn, J. S., Wei, Y., Heidary, D. K. & Glazer, E. C., May 10 2023, In: RSC Chemical Biology. 4, 5, p. 344-353 10 p.Research output: Contribution to journal › Article › peer-review
A monoadduct generating Ru(ii) complex induces ribosome biogenesis stress and is a molecular mimic of phenanthriplatin
Mitchell, R. J., Kriger, S. M., Fenton, A. D., Havrylyuk, D., Pandeya, A., Sun, Y., Smith, T., DeRouchey, J. E., Unrine, J. M., Oza, V., Blackburn, J. S., Wei, Y., Heidary, D. K. & Glazer, E. C., Feb 27 2023, In: RSC Chemical Biology. 4, 5, p. 344-353 10 p.Research output: Contribution to journal › Article › peer-review
Anticipating the unexpected
Chappell, J., Jul 2023, In: New Phytologist. 239, 2, p. 456-458 3 p.Research output: Contribution to journal › Comment/debate
A proposed FAIR approach for disseminating geospatial information system maps
Thompson, P. T., Ojha, S., Powell, C. D., Pennell, K. G. & Moseley, H. N. B., Dec 2023, In: Scientific data. 10, 1, 389.Research output: Contribution to journal › Article › peer-review
Art2 mediates selective endocytosis of methionine transporters during adaptation to sphingolipid depletion
Hepowit, N. L., Moon, B., Ebert, A. C., Dickson, R. C. & MacGurn, J. A., Jul 2023, In: Journal of Cell Science. 136, 14, jcs260675.Research output: Contribution to journal › Article › peer-review
Benchmark Dataset for Training Machine Learning Models to Predict the Pathway Involvement of Metabolites
Huckvale, E. D., Powell, C. D., Jin, H. & Moseley, H. N. B., Nov 2023, In: Metabolites. 13, 11, 1120.Research output: Contribution to journal › Article › peer-review
Bilirubin Nanoparticle Treatment in Obese Mice Inhibits Hepatic Ceramide Production and Remodels Liver Fat Content
Kipp, Z. A., Martinez, G. J., Bates, E. A., Maharramov, A. B., Flight, R. M., Moseley, H. N. B., Morris, A. J., Stec, D. E. & Hinds, T. D., Feb 2023, In: Metabolites. 13, 2, 215.Research output: Contribution to journal › Article › peer-review
Bridging the Biomarker Chasm With Interprofessional Molecular Tumor Boards
Kolesar, J. M., Arnold, S. M., Ueland, F. R. & Evers, B. M., Aug 1 2023, In: JCO Oncology Practice. 19, 8, p. 677-678 2 p.Research output: Contribution to journal › Letter › peer-review
Cannabidiol’s Multifactorial Mechanisms Has Therapeutic Potential for Aneurysmal Subarachnoid Hemorrhage: a Review
Henry, N., Fraser, J. F., Chappell, J., Langley, T. & Roberts, J. M., Jun 2023, In: Translational Stroke Research. 14, 3, p. 283-296 14 p.Research output: Contribution to journal › Review article › peer-review
Cervical spinal cord injury leads to injury and altered metabolism in the lungs
Huffman, E. E., Dong, B. E., Clarke, H. A., Young, L. E. A., Gentry, M. S., Allison, D. B., Sun, R. C., Waters, C. M. & Alilain, W. J., 2023, In: Brain Communications. 5, 2, fcad091.Research output: Contribution to journal › Article › peer-review
Chalcone Derivative CX258 Suppresses Colorectal Cancer via Inhibiting the TOP2A/Wnt/β-Catenin Signaling
Chen, X., Lv, X., Gao, L., Liu, J., Wang, W., Guo, L., Frasinyuk, M. S., Zhang, W., Watt, D. S., Liu, C. & Liu, X., Apr 2023, In: Cells. 12, 7, 1066.Research output: Contribution to journal › Article › peer-review
Computational Investigation of a Series of Small Molecules as Potential Compounds for Lysyl Hydroxylase-2 (LH2) Inhibition
Maghsoud, Y., Vázquez-Montelongo, E. A., Yang, X., Liu, C., Jing, Z., Lee, J., Harger, M., Smith, A. K., Espinoza, M., Guo, H. F., Kurie, J. M., Dalby, K. N., Ren, P. & Cisneros, G. A., Feb 13 2023, In: Journal of Chemical Information and Modeling. 63, 3, p. 986-1001 16 p.Research output: Contribution to journal › Article › peer-review
Deep learning, 3D ultrastructural analysis reveals quantitative differences in platelet and organelle packing in COVID-19/SARSCoV2 patient-derived platelets
Matharu, S. S., Nordmann, C. S., Ottman, K. R., Akkem, R., Palumbo, D., Cruz, D. R. D., Campbell, K., Sievert, G., Sturgill, J., Porterfield, J. Z., Joshi, S., Alfar, H. R., Peng, C., Pokrovskaya, I. D., Kamykowski, J. A., Wood, J. P., Garvy, B., Aronova, M. A., Whiteheart, S. W., Leapman, R. D., & 1 others , 2023, In: Platelets. 34, 1, 2264978.Research output: Contribution to journal › Article › peer-review
Development and characterization of nanobodies that specifically target the oncogenic Phosphatase of Regenerating Liver-3 (PRL-3) and impact its interaction with a known binding partner, CNNM3
Smith, C. N., Kihn, K., Williamson, Z. A., Chow, K. M., Hersh, L. B., Korotkov, K. V., Deredge, D. & Blackburn, J. S., May 2023, In: PLoS ONE. 18, 5 May, e0285964.Research output: Contribution to journal › Article › peer-review
Development of a Definition of Postacute Sequelae of SARS-CoV-2 Infection
Jun 13 2023, In: JAMA. 329, 22, p. 1934-1946 13 p.Research output: Contribution to journal › Article › peer-review
FBXO24 Suppresses Breast Cancer Tumorigenesis by Targeting LSD1 for Ubiquitination
Dong, B., Song, X., Wang, X., Dai, T., Wang, J., Yu, Z., Deng, J., Evers, B. M. & Wu, Y., Jan 1 2023, In: Molecular Cancer Research. 21, 12, p. 1303-1316 14 p.Research output: Contribution to journal › Article › peer-review
Ferric Chloride-Induced Arterial Thrombosis and Sample Collection for 3D Electron Microscopy Analysis
Joshi, S., Smith, A. N., Prakhya, K. S., Alfar, H. R., Lykins, J., Zhang, M., Pokrovskaya, I., Aronova, M., Leapman, R. D., Storrie, B. & Whiteheart, S. W., Mar 2023, In: Journal of Visualized Experiments. 2023, 193, e64985.Research output: Contribution to journal › Article › peer-review
Genomic screening methodology not requiring barcoding: Single nucleotide polymorphism-based, mixed-cell screening (SMICS)
Zhang, Z., Chen, X., Zhang, W., Liu, J., Xie, Y., Zhang, S., Stromberg, A. J., Watt, D. S., Liu, X., Wang, C. & Liu, C., Sep 2023, In: Genomics. 115, 5, 110666.Research output: Contribution to journal › Article › peer-review
Glycolytic Regulation of Intestinal Stem Cell Self-Renewal and Differentiation
Li, C., Zhou, Y., Wei, R., Napier, D. L., Sengoku, T., Alstott, M. C., Liu, J., Wang, C., Zaytseva, Y. Y., Weiss, H. L., Wang, Q. & Evers, B. M., Jan 2023, In: CMGH. 15, 4, p. 931-947 17 p.Research output: Contribution to journal › Article › peer-review