Yasir Alsiraj received an American Heart Association (AHA) Great Rivers Affiliate (GRA) Predoctoral Fellowship award for his research project titled “Sex differences in angiotensin-induced AAAs." Mr. Alsiraj is a Pharmacology doctoral candidate in Dr. Lisa Cassis lab in the Department of Pharmacology and Nutritional Sciences. Congratulations, Yasir Alsiraj!
Yu Wang received an American Heart Association (AHA) Great Rivers Affiliate (GRA) Predoctoral Fellowship award for his research project titled “The role of ACE2 in mediating sex differences in the development of obesity-hypertension in mice.” Mr. Wang is a Nutritional Sciences doctoral candidate in Dr. Lisa Cassis lab in the Department of Pharmacology and Nutritional Sciences. Congratulations, Yu Wang!
UK HealthCare and Norton Healthcare are building upon their history of collaboration to expand research and educational collaborations between the two institutions, with the goal of improving health and health care for all Kentuckians.
Beginning July 1, educational and research initiatives between UK and Norton will be lead by Dr. Stephen Wyatt, who most recently served two successful terms as the founding dean of the University of Kentucky College of Public Health.
The Barnstable Brown Kentucky Diabetes and Obesity Center hosted its fourth annual Diabetes Day on Tuesday, May 20. With a focus on current findings in obesity and diabetes research, the day's program featured presentations by nationally prominent physician-scientists as well as regional researchers chosen from abstract submissions.
Bisphenol A Increases Atherosclerosis in Pregnane X Receptor-Humanized ApoE Deficient Mice. Sui Y, Park SH, Helsley RN, Sunkara M, Gonzalez FJ, Morris AJ, Zhou C. J Am Heart Assoc. 2014 Apr 22;3(2):e000492. doi: 10.1161/JAHA.113.000492. PMID: 24755147
The mission of Nutritional Sciences is to train highly skilled nutritional scientists equipped to tackle critical nutrition-related disease and health issues and pursue promising careers in the rapidly expanding nutritional sciences field. One of the Division’s primary areas of research and training targets nutrition and chronic diseases, with a focus on obesity and associated disorders of cardiovascular disease, diabetes and cancer. Other specialty areas include nutrition and oxidative stress, nutrition and aging, clinical nutrition, animal nutrition and food science.
Can novel drug targets be identified to slow the progression of abdominal aortic aneurysms? Is a stimulated renin-angiotensin system the link between obesity and the myriad of obesity-induced cardiovascular diseases, or the development of type 2 diabetes? Do specific bioactive lipids released from platelets and/or the myocardium following myocardial infarction influence platelet function? These are some of the clinically significant pharmacologic questions addressed by researchers within the Department of Pharmacology and Nutritional Sciences.
The cancer faculty in the Department of Pharmacology and Nutritional Sciences are interested in studying the molecular basis of cancer initiation and metastatic progression. This involves using molecular biology, biochemistry, cell biology, and in vivo animal models to unravel novel signaling pathways in an effort to uncover new drug targets for treating cancer. The faculty also are attempting to understand why cancer cells develop drug resistance, a common problem in cancer treatment, and are working on identifying drugs that combat resistance.
The neuroscience faculty of the Department of Pharmacology and Nutritional Sciences focuses on brain aging and Alzheimer’s disease with an emphasis on how comorbid conditions/diseases (diabetes, stress, lack of sleep, obesity, stroke, age-related hormone loss) affect the aging progress. Other key areas of interest are in drug/alcohol abuse and the factors influencing addiction-related disease states, as well as in Down syndrome research and factors influencing brain inflammation status.
