The Department had ten publications listed in PubMed for the month of August 2020.

1: Smeltzer S, Quadri Z, Miller A, Zamudio F, Hunter J, Stewart NJF, Saji S, Lee DC, Chaput D, Selenica MB. Hypusination of Eif5a regulates cytoplasmic TDP-43 aggregation and accumulation in a stress-induced cellular model. Biochim Biophys Acta Mol Basis Dis. 2020 Aug 31:165939. doi: 10.1016/j.bbadis.2020.165939. Epub ahead of print. PMID: 32882370.

2: Frazier HN, Anderson KL, Ghoweri AO, Lin RL, Hawkinson TR, Popa GJ, Sompol P, Mendenhall MD, Norris CM, Thibault O. Molecular elevation of insulin receptor signaling improves memory recall in aged Fischer 344 rats. Aging Cell. 2020 Aug 27:e13220. doi: 10.1111/acel.13220. Epub ahead of print. PMID: 32852134.

3: Ryan RT, Havrylyuk D, Stevens KC, Moore LH, Kim DY, Blackburn JS, Heidary DK, Selegue JP, Glazer EC. Avobenzone incorporation in a diverse range of Ru(II) scaffolds produces potent potential antineoplastic agents. Dalton Trans. 2020 Aug 26. doi: 10.1039/d0dt02016h. Epub ahead of print. PMID: 32845256.

4: Leachman JR, Rea M, Cohn DM, Xu X, Fondufe-Mittendorf Y, Loria AS. Exacerbated obesogenic response in female mice exposed to early life stress is linked to fat depot-specific upregulation of leptin protein expression. Am J Physiol Endocrinol Metab. 2020 Aug 24. doi: 10.1152/ajpendo.00243.2020. Epub ahead of print. PMID: 32830551.

5: Pokrovskaya I, Tobin M, Desai R, Aronova MA, Kamykowski JA, Zhang G, Joshi S, Whiteheart SW, Leapman RD, Storrie B. Structural analysis of resting mouse platelets by 3D-EM Reveals an unexpected variation in α-granule shape. Platelets. 2020 Aug 20:1-10. doi: 10.1080/09537104.2020.1799970. Epub ahead of print. PMID: 32815431.

6: Devlin JR, Alonso JA, Ayres CM, Keller GLJ, Bobisse S, Vander Kooi CW, Coukos G, Gfeller D, Harari A, Baker BM. Structural dissimilarity from self drives neoepitope escape from immune tolerance. Nat Chem Biol. 2020 Aug 17. doi:10.1038/s41589-020-0610-1. Epub ahead of print. PMID: 32807968.

7: Yao S, Moseley HNB. A chemical interpretation of protein electron density maps in the worldwide protein data bank. PLoS One. 2020 Aug 12;15(8):e0236894. doi: 10.1371/journal.pone.0236894. PMID: 32785279; PMCID: PMC7423092.

8: Kinder JT, Moncman CL, Barrett C, Jin H, Kallewaard N, Dutch RE. Respiratory syncytial virus (RSV) and human metapneumovirus (HMPV) infections in 3-D human airway tissues expose an interesting dichotomy in viral replication, spread, and inhibition by neutralizing antibodies. J Virol. 2020 Aug 5:JVI.01068-20. doi:10.1128/JVI.01068-20. Epub ahead of print. PMID: 32759319.

9: Turcios L, Marti F, Watt DS, Kril LM, Khurana A, Chapelin F, Liu C, Zwischenberger JB, Evers BM, Gedaly R. Mitochondrial uncoupling and the disruption of the metabolic network in hepatocellular carcinoma. Oncotarget. 2020 Aug 4;11(31):3013-3024. doi: 10.18632/oncotarget.27680. PMID: 32821346; PMCID: PMC7415405.

10: Williamson ZA, Chaton CT, Ciocca WA, Korotkova N, Korotkov KV. PE5-PPE4-EspG<sub>3</sub> heterotrimer structure from mycobacterial ESX-3 secretion system gives insight into cognate substrate recognition by ESX systems. J Biol Chem. 2020 Sep 4;295(36):12706-12715. doi:10.1074/jbc.RA120.012698. Epub 2020 Jul 16. PMID: 32675282.