Image Outreach and Mentorship Center for Environmental and Systems Biochemistry Training and Education Outreach & Mentorship Visiting Researchers Developing research scientists of all levels are welcome to work side-by-side with the Center's core faculty and staff learning Metabolomics techniques and applying them to their particular research interests. Students and junior faculty from laboratories across campus, around the state, throughout the nation and from around the world contribute to the interdisciplinary cross-pollination of ideas that is a very important objective for the Center. Please contact Drs. Fan, Lane and Higashi for opportunities to visit.Recent contributions have been made by the following: Dan Crooks-NCI Bethesda. Metabolomics of SDH mutant kidney cancers Nicola Consolini-U. Bologna. SIRM studies of COPD Marilia Dias- Sao Paulo. shRNA of enzymes for SIRM studies in cancer cells. Katarina Fritz-Graz, Austria. SIRM studies of ATGL Sandra Gomes - Sao Paulo. Sample preparation for SIRM studies of glutaminase C in cancer cells. Scott Jones - Medicine at University of Louisville. Natural products involved in pre-Parkinson's disease symptoms. Anne Le - Johns Hopkins University. SIRM analysis of MYC expression in cancer cells. Santiago Moralli - University of Barcelona. High-throughput metabolite analysis, specifically the study of the lipidome and its changes during cell cycle progression and tumor transformation. Jason Podrabsky - Oregon State. GC-MS analysis of killifish embryos. Miriam Porquet - University of Barcelona. Study of metabolic and lipid profiles of mouse embryogenic fibroblast cell lines using LTQ FT MS and GCMS techniques and software to describe the metabolic importance of the lack of two key enzymes (CDK4 and CDK6) in the cell cycle. Chris Ricketts and Youfeng Yang - NCI SIRM studies of metabolic reprogramming in fumarate hydratase null cells Pankaj Seth - Beth Israel Deaconess, Boston. SIRM analysis of LDH-A knockdowns in cancer cells. Mariia Yuneva - University of California, San Francisco. Molecular regulatory mechanisms of the MYC oncogene in mammalian cells Jack Hardwick-Oxford University. Structure of 5formylC modified DNA Undergraduate Mentorship, Education, and Training Undergraduate students participate in all aspects of research including conducting their own projects, developing analytical methods, and preparing platform and poster presentations. Undergraduate Seminars Center faculty give metabolomics presentations tailored specifically for undergraduate students to promote a broader dissemination of the field and what it has to offer for future scientific careers. October 2007- North Eastern Illinois University: Andrew Lane " Biological Chemistry: Structure, Thermodynamics and Function " Fall 2010 - Berea College: Dr. Teresa Fan presenting "Metabolism: Old or Gold?". Fall 2010 - Huntingdon College: Dr. Hunter Moseley presenting "Metabolic Modeling of Converging Metabolic Pathways. Analysis of Non-Steady State Stable Isotope-Resolved Metabolomics of UDP-GlcNAc and UDP-GalNAc." August 2011 - Summer Student Program, JG Brown Cancer Center: "Clinical Applications of Stable Isotope-Resolved Metabolomics (SIRM) in Non Small Cell Lung Cancer". Andrew Lane July 2012 - Summer Student Program, JG Brown Cancer Center: "Understanding Cancer Through Metabolism". Andrew Lane Image College Students Mentored by Center Faculty Student Dates Hometown Mentor Alex Belshoff June 2007-May 2008 Louisville KY Teresa Fan Sabine Dhakal June-Oct. 2007 Nepal Teresa Fan Kathleen Marshall June 2007-May 2008 Leitchfield KY Teresa Fan Mark Capece 2008 Davis CA Teresa Fan Ben King 2008 Teresa Fan Mabruk Habib Summer 2008 Andrew Lane Martin McKinney Summer 2008 Andrew Lane Sabrina Shatzman 2009-2012 Teresa Fan Gregory Bousamra Summer 2010 Louisville KY Andrew Lane Zelalem Mekonnen Summer 2011 Teresa Fan Austin McCuiston Summer 2011 Andrew Lane Laura Cornwell 2011-2013 Louisville, KY Andrew Lane Connor Kinslow 2013 New York, NY Andrew Lane High School High School students participate in many aspects of our metabolomics research efforts to promote early interest in science. Many use this opportunity for senior science projects and present their efforts at regional science fairs. High School Students Mentored by Center Faculty Student Grade Date Mentor Doug Lattimore High School March 12 2005 Teresa Fan Patrick Oechsli Junior High March 12 2005 Teresa Fan Li Zhang High School March 11 2006 Teresa Fan Nambi Arumugam High School March 11 2006 Teresa Fan Nambi Arumugam High School February 1 2007 Teresa Fan Monali Haldankar High School Fall 2008 Andrew Lane Anna Duan High School Fall 2008 Andrew Lane Anna Duan High School Fall 2010 Andrew Lane Justin Bunch Groton Fellow 2014 Teresa Fan Broader Community Center faculty and staff have also participated in many local conferences with audiences ranging from secondary school teachers to environmentalists. These presentations serve to educate the community about the discipline of Metabolomics and offer the instructional services of the Center to the community it serves. The following is a partial list: September 15, 2007 - Kentucky Association for Environmental Education: Metabolomics in bioavailability, mechanism, and biomarker discovery November 2, 2007 - Kentucky Science Teachers Association: Metabolomics and Isotopomer analysis
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