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Yadi Wu, PhD




  • Associate Professor
  • Markey Cancer Center

College Unit(s)

Other Affiliation(s)
  • Markey Cancer Center - Affiliated Faculty
  • Pharmacology and Nutritional Sciences Center Affiliated Faculty

Biography and Education


Ph.D in immunology; Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, Shanghai, China

Selected Publications

1. Wu Y*, Wang Y, Yang X, Kang T, Zhao Y, Wang C, Evers BM, and Zhou BP*. Deubiquitinase USP28 Confers Breast Cancer with Stem Cell-like Traits by Stabilizing LSD1. Cell Reports, 2013, In press (* Correspondence Author) 2. Dong C, Yuan T*, Wu Y*, Wang Y*, Fan TW, Yao J, Lin Y, St Clair D, Evers BM, and Zhou BP. Loss of FBP1 by Snail-mediated Repression Provides Metabolic Advantages in Basal-like Breast Cancer. Cancer Cell, 23(3):316-31, 2013 (* Contribute equally). 3. Dong C, Wu Y, Wang Y, Wang C, Chi Y, Evers BM, and Zhou BP. Interaction with Suv39H1 is critical for Snail-mediated E-cadherin Repression in Breast Cancer. Oncogene, 32(11):1351-62, 2013. 4. Dong C, Wu Y, Wang Y, Yao J, Yu Y, Rychahou PG, Evers BM, and Zhou BP. G9a Interacts with Snail and is Critical for Snail-mediated E-cadherin Repression in Breast Cancer. J Clin Invest, 122(4):1469-86, 2012. 5. Lin Y*, Wu Y*, Li J, Dong C, Ye X, Chi Y.-I, Evers BM, and Zhou BP. The SNAG Domain of Snail1 Functions as a Molecular Hook for Recruiting Lysine-specific Demethylase 1, EMBO J, Jun 2;29(11):1803-16, 2010. (*Co-first author) Paper was selected by Faculty 1000 Commentary Coverage: Christofori G, Snail1 links transcriptional control with epigenetic regulation, EMBO J, 29, 1787-1789, 2010 6. Wu Y and Zhou BP. Snail: More than Epithelial-Mesenchymal Transition. Cell Adhesion & Migration, 4(2), 199-203, 2010. 7. Wu Y and Zhou BP. TNFα/NF-κB/Snail pathway in cancer cell migration and invasion, British Journal of Cancer, 102(4):639-44, 2010. 8. Jin J, Yu Y, Zhang T, Zhou X, Zhou J, Jia L, Wu Y, Zhou BP, and Feng Y. Snail is Critical for the Metastasis of Ovarian Carcinoma, International Journal of Cancer, 126(9):2102-11, 2010. 9. Wu Y and Zhou BP. Inflammation: a driving force speeds cancer metastasis, Cell Cycle, 8(20), 2009. 10. Wu Y, Deng J, Rychahou PG, Qiu S, Evers BM, and Zhou BP. Stabilization of Snail Is Required for Inflammation-Induced Cell Migration and Invasion, Cancer Cell, 15(5):416-28, 2009. Featured Article of May 2009 issue of Cancer Cell with commentary from: Preview: Yang CC, Wolf DA. Inflamed snail speeds metastasis. Cancer Cell, 15(5):355-7, 2009. Leading Edge: Smith OM, Metastasis proceeds at more than a Snail’s pace, Cell, 137, 591, 2009. Nature Cell Migration Gateway: Baumann K, Inflammation-induced metastasis: Moving at a Snail's pace, June 2009. 11. Wu Y, Evers BM, and Zhou BP. Small C-terminal Domain Phosphatase Enhances Snail Activity through Dephosphorylation, J Biol Chem, 284(1):640-8, 2009.

Pubmed Publications