Olivier Thibault, PhD
- Professor of Neuroscience
- Co-Director Sanders-Brown Intravital Imaging Facility
- Graduate Faculty of Nutritional Sciences
- Affiliate Member of the Sanders-Brown Center on Aging
- Barnstable Brown Diabetes Center Member
- MD/PhD Program Mentor
- Pharmacology Graduate Advisory Committee
- Pharmacology and Nutritional Sciences Primary Faculty
- Nutritional Sciences Graduate Faculty
Biography and Education
1989-1993 Ph.D. in Neuroscience (Mentor: Dr. Philip Landfield), Bowman Gray School of Medicine, Department of Anatomy.
1993-1995 Postdoctoral fellow, Dr. Philip Landfield, University of Kentucky, Department of Pharmacology.
1995-1997 Research Associate, University of Kentucky, Department of Pharmacology.
1998-2003 Research Assistant Professor, University of Kentucky, Department of Molecular and Biomedical Pharmacology
2004-2009 Assistant Professor, University of Kentucky, Department of Molecular and Biomedical Pharmacology
2009-2016 Associate Professor, University of Kentucky, Department of Pharmacology and Nutritional Sciences
2016-Present Professor, University of Kentucky, Department of Pharmacology and Nutritional Sciences
WE ARE A NEUROSCIENCE LAB WITH STRONG INTERESTS IN THE IMPACT OF INSULIN ON THE BRAIN.
Intersection of two fields: dysregulation of calcium-dependent cellular mechanisms of learning and memory with brain aging and links between peripheral metabolic dysregulation and cognitive decline. We have shifted our focus from understanding cognitive decline with aging using single cell electrophysiology and imaging of calcium, to understanding calcium dysregulation in networks of neurons and astrocytes in vivo, using somatosensory cortex 2-photon imaging. We hope this approach, combined with intranasal insulin, can infer on gait and ambulatory dysregulation with age and also identify novel therapies for reducing falls in the elderly. We have modified the beta subunit of the insulin receptor and have published four brain aging and insulin study to offset cognitive decline
People in the lab:
- Sami L. Case (Graduate Student)
- Sophyia Sims (Graduate Student)
- Ruei-Lung Lin, MS, (Scientist)
- Jackie Rhinehart (Research Analyst)
- Nicholas Wright (Research Analyst)