Two independent groups of researchers led by Sidney "Wally" Whiteheart, PhD, at the University of Kentucky, and Dr. Charles Lowenstein, at the University of Rochester, have published important studies exploring the role that a gene called STXBP5 plays in the development of cardiovascular disease. According to Whiteheart, previous genome-wide association studies (GWAS) identified a gene called STXBP5 as a factor that regulates a protein called Von Willebrand factor (VWF). VWF is an important contributor to normal blood clotting.

As a reminder, an Internal Approval Form (IAF) is no longer routinely required for non-competing progress reports. This change primarily effects multiple year awards from the National Institutes of Health (NIH). An IAF will still be required for significant changes (for instance, if there is a 25% or greater change in budget from the proposal that was originally routed, if a co-Investigator is added or if the Enrichment distribution changes). 

You are probably aware that the federal Office of Management and Budget (OMB) has made a major change to the underlying guidance by which university recipients of federal awards have operated for decades. OMB combined eight separate circulars, applicable to different types of grantee organizations, into a single document, “Uniform Administrative Requirements, Cost Principles, and Audit Requirements for Federal Awards,” commonly referred to as the Uniform Guidance (UG).

Starting in October 2014 (just a few weeks away!) eRA Commons Usernames for graduate and undergraduate student project roles will be required for both the PHS 2590 Non-Competing Continuation Progress Report and Research Performance Progress Report (RPPR).

Public Law 110-81: Honest Leadership and Open Government Act of 2007  imposes stringent requirements on universities and other organizations engaged in lobbying. The University of Kentucky, as a registered lobbying entity, must exercise comprehensive oversight over all lobbying activities undertaken on behalf of the University and must file quarterly disclosure reports with the Secretary of the Senate and the Clerk of the House of Representatives.

LEXINGTON, Ky. (Sept. 9, 2014) – The University of Kentucky has been awarded research grants totaling $1.26 million by The American Heart Association. 

The nine grants will fund research underway at the Gill Heart Institute's Saha Cardiovascular Research Center and the University of Kentucky College of Medicine. 

Tori Stromp was awarded the Council on Cardiovascular Radiology and Intervention travel award to the upcoming American Heart Association Scientific Sessions in Chicago, IL. This award recognizes meritorious work by young investigators in training, encourages participation in the AHA Scientific Sessions, and provides a stipend to help defer travel expenses to present their work at the AHA Scientific Sessions. The award ($1,500) is distributed to a select number of young investigators based on the score of the submitted abstract.

The UK College of Medicine has launched a new systems-based curriculum that integrates basic science and clinical concepts early in medical school through interactive instructional methods. Want to know what our medical students are saying about these new curricular enhancements? Watch this brief video.

A new study by University of Kentucky researchers has identified a novel molecule named Arylquin 1 as a potent inducer of Par-4 secretion from normal cells. Par-4 is a protein that acts as a tumor suppressor, killing cancer cells while leaving normal cells unharmed. Normal cells secrete small amounts of Par-4 on their own, but this amount is not enough to kill cancer cells.
Did you know that you can help others by participating in research? Health-focused research affects every aspect of our lives, from the medications we take to the health of our environment. Researchers are working hard to identify new treatments and strategies to improve the health of our communities, but research needs healthy volunteers and volunteers with medical conditions in order to succeed.