NIH recently updated policies regarding application submissions.  That update allowed resubmission of an A1 application as an A0.  One of the restrictions outlined in the policy update states that the second A0 submission can not reference any previous reviews.  NIH is rejecting any application making reference to previous reviews.  To read more of the policy, click here.  For questions, contact your GPS.

[From NIH eSubmission Items of Interest - September 18, 2014]

Systematic Application Compliance Checking – What It Is and What It’s Not 

Automated enforcement of business rules by NIH eRA systems plays an important role in the application submission process – it helps you and it helps NIH. Understanding what that role covers can be the difference between your application moving forward to review and not. 

System-enforced application validations are what they are – nothing more, nothing less. 

In response to the third cycle of NCI Alliance activity, we are organizing a team to work on a proposal for  “NCI Center for Cancer Nanotechnology Excellence”. The UK proposal is entitled  “RNA Nanotechnology Center for Cancer Therapy".   We strongly encourage UK faculties to participate in this proposal.  Please contact Peixuan Guo (peixuan.guo@uky.edu) for a recommendation to a project leader.  The deadline is the beginning of November.

Mechanisms of aortic aneurysm formation: translating preclinical studies into clinical therapies.
Heart. 2014 Oct 1;100(19):1498-1505. doi: 10.1136/heartjnl-2014-305648. Epub 2014 Jul 24.
Davis FM, Rateri DL, Daugherty A.
PMID:25060754

Abstract:

Two independent groups of researchers led by Sidney "Wally" Whiteheart, PhD, at the University of Kentucky, and Dr. Charles Lowenstein, at the University of Rochester, have published important studies exploring the role that a gene called STXBP5 plays in the development of cardiovascular disease. According to Whiteheart, previous genome-wide association studies (GWAS) identified a gene called STXBP5 as a factor that regulates a protein called Von Willebrand factor (VWF). VWF is an important contributor to normal blood clotting.
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As a reminder, an Internal Approval Form (IAF) is no longer routinely required for non-competing progress reports. This change primarily effects multiple year awards from the National Institutes of Health (NIH). An IAF will still be required for significant changes (for instance, if there is a 25% or greater change in budget from the proposal that was originally routed, if a co-Investigator is added or if the Enrichment distribution changes). 

You are probably aware that the federal Office of Management and Budget (OMB) has made a major change to the underlying guidance by which university recipients of federal awards have operated for decades. OMB combined eight separate circulars, applicable to different types of grantee organizations, into a single document, “Uniform Administrative Requirements, Cost Principles, and Audit Requirements for Federal Awards,” commonly referred to as the Uniform Guidance (UG).

Starting in October 2014 (just a few weeks away!) eRA Commons Usernames for graduate and undergraduate student project roles will be required for both the PHS 2590 Non-Competing Continuation Progress Report and Research Performance Progress Report (RPPR).

Public Law 110-81: Honest Leadership and Open Government Act of 2007  imposes stringent requirements on universities and other organizations engaged in lobbying. The University of Kentucky, as a registered lobbying entity, must exercise comprehensive oversight over all lobbying activities undertaken on behalf of the University and must file quarterly disclosure reports with the Secretary of the Senate and the Clerk of the House of Representatives.

LEXINGTON, Ky. (Sept. 9, 2014) – The University of Kentucky has been awarded research grants totaling $1.26 million by The American Heart Association. 

The nine grants will fund research underway at the Gill Heart Institute's Saha Cardiovascular Research Center and the University of Kentucky College of Medicine.