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A new study led by University of Kentucky Markey Cancer Center researcher Peter Zhou shows that targeting Twist, a nuclear protein that is an accelerant of the epithelial-mesenchymal transition (EMT) program in human cells, may provide an effective approach for treating triple-negative breast cancer. Triple-negative breast cancer has an activated EMT program, which is a process that provides cells with the increased plasticity (or flexibility) to adapt to stressed environments during embryonic development, wound healing, tissue fibrosis and metastasis.
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A career in emergency medicine requires a commitment to helping patients in the most critical situations. For demonstrating her passion for this field, University of Kentucky medical student Jennifer Cotton has received a $500 scholarship from the American Academy of Emergency Medicine/Resident and Student Association (AAEM/RSA). As part of the honor, Cotton was invited to be recognized during the 20th Annual AAEM Scentific Assembly in New York, on Feb. 12. Nominations for the AAEM/RSA Student Scholarship were accepted in the fall of 2013.
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UK HealthCare has announced plans to lease and renovate the former Dillard's location at Turfland Mall on Harrodsburg Road for consolidation and relocation of some of its primary care and specialty outpatient clinics. UK HealthCare will be the anchor tenant for the first floor of the building utilizing approximately 85,000 square feet, officials said.
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Ardis Dee Hoven, President of the American Medical Association (AMA), will provide a special guest lecture as part of the UK College of Pharmacy’s Advocacy Day at noon on February 5, 2014 in room 124 of the BioPharm Complex. Dr. Hoven, who became the 168th president of the AMA in June 2013, will deliver her talk “The AMA, Pharmacists and the Future of Healthcare,” addressing the importance of physician-pharmacist collaboration and pharmacists as a crucial member of the physician-led healthcare team. Dr.
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Renowned chemist, novelist and playwright Carl Djerassi, known for his work in organic chemistry and as a father of insect and human birth control, will take part in several events being held Feb. 13-15, at the University of Kentucky. During his visit to the Bluegrass, Djerassi will participate in three events. He will first serve as the featured speaker at a luncheon for business and academic leaders.
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Letcher County community leaders and health care providers gathered in Whitesburg on Jan. 23, to celebrate a new partnership among Mountain Comprehensive Healthcare Corporation (MCHC), Appalachian Regional Healthcare (ARH), and UK HealthCare’s Gill Heart Institute. Dena Sparkman, CCEO of Whitesburg ARH, welcomed more than 100 invited guests to the event held at the Pine Mountain Grill in Whitesburg. Remarks were provided by Joe Grossman, president and CEO of Appalachian Regional Healthcare; University of Kentucky Vice President for Health Affairs Dr.
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One doesn't expect that the chief of neurology would have a lot of downtime.  But, as Dr. Michael Dobbs explains, working as a neurologist at UK HealthCare can sometimes mean just that.

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A new study by University of Kentucky researchers shows that women who never or rarely screen for breast cancer are also unlikely to receive screening for cervical cancer. The study also identified four key barriers independently associated with the lack of these cancer screenings in Appalachian women. Published in Women & Health, the study focused on six rural counties in Appalachian Kentucky. Researchers conducted in-person interviews with 222 women to assess their adherence (or lack thereof) to cancer screening guidelines.
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For most of us, vacation days are used for relaxing, traveling, sight-seeing, or even just doing nothing. For some University of Kentucky employees, however, those vacation days are put to use serving those who are less fortunate and in need of good medical care. Recently, pediatric critical care physician Dr. Scottie Day led one such effort to help bring basic medical care to children in Haiti.

A new lecture series presented by mUsiKcare will highlight wellness and health care benefits of music programs like the UK piano courses for individuals 50 years of age and older. A transcript of this video can be found here. Video by Jenny Wells/UK Public Relations and Marketing.

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Donna Wilcock, assistant professor in the University of Kentucky College of Medicine Department of Physiology and the UK Sanders-Brown Center on Aging, has been invited to join the editorial board of The Journal of Neuroscience in 2014 as an associate editor in the Neurobiology of Disease section. She was been selected by the senior and reviewing editors of the journal based on her expertise and history of reviews. As an associate editor, Wilcock will provide frequent reviews as well as suggesting appropriate reviewers for manuscripts.
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Ana Bastos-Carvalho, a visiting scholar in the Ambati research group in the Department of Ophthalmology and Visual Sciences at the University of Kentucky College of Medicine, received the Global Ophthalmology Research Award from Bayer HealthCare for her research, "Mechanisms of geographic atrophy expansion in age-related macular degeneration." http://www.bayer-ophthalmology-awards.com/html/b-about-c.html “We are studying age-related macular degeneration (AMD), the disease responsible for most cases of legal blindness in the American elderly population”, Bastos-Carvalho said.
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There's a proverb in the business world that says, "If you don’t know, hire someone who does." In the world of translational research, the saying might go like something this: "If you don't have the expertise or resources, collaborate with someone who does." The nature of translational science -- the process of turning a basic science discovery into applications for human patients -- is inherently multidimensional.
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A new study led by University of Kentucky researchers suggests that activating the tumor suppressor p53 in normal cells causes them to secrete Par-4, another potent tumor suppressor protein that induces cell death in cancer cells. This finding may help researchers decipher how to inhibit the growth of tumors that have become resistant to other treatments. Loss of the tumor suppressor p53 often contributes to therapy resistance in tumors.
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The University of Kentucky Area Health Education Center (AHEC) is now accepting applications for the 2014 Summer Enrichment Program (SEP) and Health Researchers Youth Academy (HRYA), two health career summer camps hosted annually each summer.
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Gretchen Norling Holmes, assistant director of research at the University of Kentucky Center of Excellence in Rural Health (CERH) in Hazard, has been selected by the National Rural Health Association (NRHA) as a 2014 Rural Health Fellow. Following the completion of a competitive review process, Holmes was one of 15 fellows selected from across the nation to participate in a yearlong, intensive program aimed at developing leaders who can articulate a clear and compelling vision for rural America. “We are very pleased to announce this new class of fellows as this program enters its eighth ye
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Dr. Jayakrishna Ambati, professor and vice chair in the Department of Ophthalmology and Visual Sciences and professor in the Department of Physiology at the University of Kentucky College of Medicine,is one of 11 recipients of the 2014 Harrington Scholar-Innovator Awards given by the Harrington Discovery Institute at University Hospitals (UH) Case Medical Center.
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In a time when competition for federal research funding  is tougher than ever before, the University of Kentucky has been awarded one of the largest health grants ever made to the institution: an $11.3 million National Institutes of Health (NIH) grant  supporting research focusing on issues that plague the Commonwealth - the twin scourges of obesity and cardiovascular disease.

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Dr. Mark Evers, director of the University of Kentucky Markey Cancer Center, professor and vice-chair for research in the Department of Surgery and Markey Cancer Foundation Endowed Chair, has been elected the new president of the Southern Surgical Association. One of the nation’s leading medical groups, the association is dedicated to furthering the study and practice of surgery, especially in the Southern states.
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The Health Careers Enrichment Camp offered each summer by the University of Kentucky Center of Excellence in Rural Health (CERH) and the Southeast Kentucky Area Health Education Center (AHEC) has received a 2013 Innovation Award from the Appalachian Innovation Collaborative (AIC), a group whose focus is on educational excellence and economic development in Eastern Kentucky. The award was presented by former Gov.