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A multi-site clinical trial led by researchers at the University of Kentucky Center on Drug and Alcohol Research (CDAR) has demonstrated the effectiveness of CAM2038, a potentially transformative buprenorphine therapy for moderate-to-severe opioid use disorders.

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Radiation therapy saves countless lives, but in rare cases, it can cause a debilitating, long-term complication when used on the brain. Around three to five percent of patients who receive radiation for brain tumors, or arteriovenous malformations (AVM), develop radiation necrosis, where the brain tissue around the targeted lesion becomes injured and dies. The condition can be disabling, causing severe headaches, nausea and vomiting, cognitive problems and neural dysfunction.
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In February, institutions around Lexington will celebrate Heart Month with activities that promote healthy habits such as exercise, smoking cessation, stress reduction and improved diet. 

UK HealthCare's Gill Heart Institute will focus on ways to make your diet more heart-healthy with a celebration and information about simple ingredient substitutes that can make your transition to a healthy diet easier.

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The rate of Americans suffering from food allergies, including a life-threatening peanut allergy, has dramatically increased in the past few decades. 

Peanut allergies are the leading cause of death caused by food-induced asphyxia, although death from a peanut allergy is rare. Peanut allergies typically begin during early childhood and persist into adulthood.  

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Ann Coker, professor in the University of Kentucky College of Medicine and Verizon Wireless Endowed Chair in the UK Center for Research on Violence Against Women (CRVAW), will host a presentation this Tuesday on the link between violence against women and cancer. The presentation, titled “Violence against women and cancer incidence, care and recovery,” will be held at 8 a.m. Tuesday, Jan. 17, in room 263 of the Medical College Building (MC263). Violence against women is defined as sexual assaults or sexual abuse during childhood, and intimate partner physical, sexual or psychological abuse.
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The American College of Cardiology has named Gill Heart Institute's Dr. David J. Moliterno, the new editor-in-chief of JACC: Cardiovascular Interventions. Moliterno is the Jack M. Gill Chair and professor of the Department of Internal Medicine at the University of Kentucky. He is also a member of the interventional cardiology faculty at the UK Gill Heart Institute.
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At the beginning of the year, many women (and men) set resolutions around health and fitness, often focusing on weight loss. But one of the most important habits women can form revolves around regular health checks, particularly for preventable cancers. January is cervical cancer awareness month. Unfortunately, Kentucky ranks in the top 10 in the country for cervical cancer incidence and death rates – a dire statistic considering cervical cancer is largely preventable through vaccination and screening. The human papillomavirus (HPV) causes virtually all cases of cervical carcinomas.
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A new study by University of Kentucky Markey Cancer Center researchers shows that chloroquine – a drug currently used to treat malaria – may be useful in treating patients with metastatic cancers. Published in Cell Reports, the study showed that chloroquine induced the secretion of the tumor suppressor protein Par-4 in both mouse models and in cancer patients in a clinical trial.
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Michele Staton-Tindall grew up in rural Appalachia during a time when people felt so safe they didn’t even lock their doors at night. The ensuing drug epidemic that now ravages her former home has dramatically impacted the lives of the Appalachian people and broken that sense of security.

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Equestrian sports contributes to the highest percentage of traumatic brain injuries (TBI) in sports, based on findings in the National Trauma Databank.
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 Laura Dawahare | UKnow | Jan. 6, 2017 

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Alan Daugherty, senior associate dean for research at the University of Kentucky College of Medicine, was recently approved to renew his contract as editor-in-chief of Arteriosclerosis, Thrombosis, and Vascular Biology: Journal of the American Heart Association (ATVB) for a second five-year term. ATVB is one of the five core journals of the American Heart Association. As editor of ATVB, Daugherty’s primary focus is on publishing the most important new research studies related to a spectrum of vascular diseases.
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An array of scientific evidence demonstrates a correlation between diets high in fat and cholesterol content and blockages in the arteries, which lead to cardiovascular disease (CVD).

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It wasn't until he could no longer open his mouth to take a bite of a cheeseburger that Winchester resident Barry Warner knew something was seriously wrong.

In fall 2009, Warner had just returned from a golf trip where he'd begun experiencing some mildly annoying symptoms: a little discomfort while eating; a reduced appetite. But he pushed on, assuming the issue would clear up on its own.

"I have a high threshold for pain," Warner said. "I don't always go to the doctor for everything. I usually let it run its course."

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Yasir Al-Siraj, a Ph.D. candidate in the University of Kentucky College of Medicine Department of Pharmacology and Nutritional Sciences, is the lead author of a paper published in Circulation, a leading journal on cardiovascular medicine. 

The article, “Female Mice with an XY Sex Chromosome Complement Develop Severe Angiotensin II-Induced Abdominal Aortic Aneurysms,” was co-authored by UK colleagues Sean E. Thatcher, Richard Charnigo, Kuey Chen, Eric Blalock, Alan Daugherty and Lisa Cassis.

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LEXINGTON, Ky. (Dec. 14, 2016) —

"also.... just because

I am working out the flavor for the 

1812 Overture

I will most likely put it into a lolli 

this is an incredible challenge

as it is making me cry while I listen…"

Taria Camerino's poetic email sums up her passion for helping people explore how flavor perception is influenced by more than the tongue.  Her emotion is genuine: as a gastral synesthete, she experiences ALL senses as taste.

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Linda Van Eldik, director of the University of Kentucky Sanders-Brown Center on Aging, was awarded a "Part the Cloud" translational research grant from the Alzheimer's Association.
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Carol Elam, associate dean of Admissions and Institutional Advancement at the University of Kentucky College of Medicine, has been named the recipient of the 2016 Southern Group on Educational Affairs (SGEA) Career Educator Award. The award acknowledges Elam’s leadership and contributions to medical education. As a professor of behavioral science, associate dean for admissions and institutional advancement, and director of medical education research at the college, Elam has been an avid supporter of student-centered initiatives focused on education and student well-being.
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The University of Kentucky Sanders-Brown Center on Aging (SBCoA) has been selected to participate in a multicenter, landmark $3.6 million grant from the National Institutes of Health to identify biomarkers for vascular cognitive impairment and dementia (VCID). UK was one of just seven sites selected for the five-year NIH's National Institute of Neurological Disorders and Stroke (NINDS) grant. The other sites are Boston University, Rush University, Johns Hopkins, University of Southern California, UCSF/UC-Davis and the University of New Mexico.
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Two faculty members from the University of Kentucky have received three of four funded awards from the National Institutes of Health (NIH) to develop responses to the opioid injection epidemic that can be implemented by public health systems in rural communities. Carrie Oser, an associate professor of sociology in the UK College of Arts & Sciences, was awarded a one-year, $150,000 grant for her project "Improving Outcomes after Prison for Appalachian PWIO (People who Inject Opioids): The Role of XR-NTX & Networks." This research aims to understand the factors and barriers related to a