CHET Faculty Member Publishes Paper in The Lancet Healthy Longevity Journal

Congratulations to Dr. Meredith Duncan, CHET' Biostatistics Core Coordinator, who recently published an article in The Lancet Healthy Longevity entitled, "Association between HIV and incident pulmonary hypertension in US Veterans: a retrospective cohort study." 

According to Duncan and colleagues, "Small studies have suggested that people living with HIV have increased incidence of pulmonary arterial hypertension compared with those without HIV. Previous studies with echocardiography data examining the association between HIV and pulmonary hypertension in large cohorts have been cross-sectional and have therefore been unable to establish temporality between HIV infection and development of pulmonary hypertension. Thus, longitudinal studies are needed to establish whether HIV is associated with incident pulmonary hypertension and whether higher levels of detectable HIV viraemia increase the risk of pulmonary hypertension. To answer these questions, we used data from the Veterans Aging Cohort Study (VACS), a large contemporary cohort of veterans with HIV and of demographically similar veterans without HIV infection with serial measurements of pulmonary artery systolic pressure (PASP) and robust data on comorbidities. This study builds on our previous work assessing prevalent pulmonary hypertension in VACS by using serial measurements of PASP measured by echocardiography extracted from medical records using natural language processing tools."

You can read the full article here: https://www.thelancet.com/journals/lanhl/article/PIIS2666-7568(21)00116-1/fulltext