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Jagannadha Avasarala, MD, PhD

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Positions

  • Professor
  • Director of the UK Comprehensive Care Center for MS and Neuroimmunology

College Unit(s)

Research

CURRENT RESEARCH PROJECTS

  1. Study of CD20 cell populations in patients with Ocrevus.
  2. Use of a smartphone App to study optic nerve disease.
  3. Fundus photography as a tool to decipher disease using big data
  4. Data analytics to track disease patterns in MS
  5. Optical coherence tomography in NMOSD and MS.

CLINICAL TRIALS

  1. CLICK-MS study
  2. Redcap data collection for African-Americans with MS and NMOSD (on clinicaltrials.gov)
  3. Syneos Health collaboration to enlist UKMC as a phase 3 clinical trials center for NMOSD
  4. Syneos Health collaboration to enlist UKMC as a phase 3 clinical trials center for NMOSD.

Selected Publications

Forkhead box C1 gene variant causing glaucoma and small vessel angiopathy can mimic multiple sclerosis.

Avasarala JR, Jones JR, Rogers CR.

Mult Scler Relat Disord. 2018 

 

Anti-CD20 Cell Therapies in Multiple Sclerosis-A Fixed Dosing Schedule for Ocrelizumab is Overkill.

Avasarala J.

Drug Target Insights. 2017 Oct 25;11:1177392817737515.

 

Approach to Fingolimod-Induced Lymphopenia in Multiple Sclerosis Patients: Do We Have a Roadmap?

Avasarala J, Jain S, Urrea-Mendoza E.

J Clin Pharmacol. 2017 Nov;57(11):1415-1418. 

 

Is a Neurologist Needed to Diagnose Acute Stroke in the Emergency Department?: Too Many Cooks Might Spoil the Broth.

Avasarala J.

JAMA Neurol. 2016 Nov 1;73(11):1273-1274.

 

Vitamin D deficiency in multiple sclerosis: Should testing and treatment be based on racial background?

Avasarala J, Zachariah P.

J Neurol Sci. 2015 Nov 15;358(1-2):417-8. 

 

Clinically isolated syndrome--Rethinking the diagnosis.

Avasarala JR.

J Neurol Sci. 2015;353(1-2):79-80.

 

The TOUCH program and natalizumab: Fundamental flaw in patient protection.

Avasarala J.

Version 3. F1000Res. 2015 Dec 15 [revised 2016 Jan 1];4:1450. 

 

Inadequacy of clinical trial designs and data to control for the confounding impact of race/ethnicity in response to treatment in multiple sclerosis.

Avasarala J.

JAMA Neurol. 2014 Aug;71(8):943-4. 

 

Microarray analysis in B cells among siblings with/without MS - role for transcription factor TCF2.

Avasarala JR, Chittur SV, George AD, Tine JA.

BMC Med Genomics. 2008 Jan 31;1:2.

 

Can a diagnosis of multiple sclerosis be made without ruling out neuromyelitis optica spectrum disorder?

Jagannadha Avasarala, Creed Pettigrew, Paige Sutton, Zain Guduru, Julie Gurwell, Brent S Sokola, Selina Mullins, Can a diagnosis of multiple sclerosis be made without ruling out neuromyelitis optica spectrum disorder ?, Multiple Sclerosis and Related Disorders. Volume 40,2020, 101949, ISSN 2211-0348,