Profile picture for user hsa243

Hisashi Sawada, PhD


741 South Limestone Street, Biomedical/Biological Sciences Research Building, Rm: B251


  • Assistant Professor

College Unit(s)

Other Affiliation(s)
  • CVRC - Core Faculty

Biography and Education


04/2002 - 03/2008: MD, Hyogo College of Medicine, Hyogo, Japan

04/2010 - 09/2015: PhD, Hyogo College of Medicine, Graduate School of Medicine, Hyogo, Japan

10/2015 - 10/2020: Postdoctoral Fellow, University of Kentucky, Lexington, KY


I received M.D. degree in 2008 and worked as a cardiologist for 7 years. In this period, I experienced many cases of aortic diseases including aneurysms and dissections. I became interested in the pathophysiology of aortic diseases, and started basic researches. I am particularly interested in the embryonic origins of smooth muscle cells in the ascending aorta. Smooth muscle cells in the ascending aorta are derived from two different embryonic origins, cardiac neural crest and second heart field. These origins show a distinct distribution and contribute to the pathophysiology of aortic diseases. I am investigating functional differences of these origins using proteomic and transcriptomic analyses in mice.