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William Stoops




  • Professor, Department of Behavioral Science with Joint Appointments in the Departments of Psychiatry and Psychology
  • Faculty, Center on Drug and Alcohol Research
  • Director, Clinical Research Support Office
  • Associate Director for Clinical Research, Substance Use Priority Research Area
  • Director, Regulatory Knowledge and Support Core, Center for Clinical and Translational Science

College Unit(s)



Biography and Education


Dr. William Stoops, a Professor in the Departments of Behavioral Science, Psychiatry and Psychology at the University of Kentucky, earned his Bachelor’s degree in Psychology from Davidson College in Davidson, NC and his Master’s degree and PhD in Psychology from the University of Kentucky. His research, continuously funded by NIH since 2008, evaluates the behavioral and pharmacological factors that contribute to drug use disorders, focusing primarily on stimulant drugs. He is leading a large clinical trial evaluating non-abstinence outcomes in cocaine use disorder and is also principal investigator on human laboratory studies determining the role of orexin and serotonin 5-HT1b systems in the abuse related effects of cocaine. He recently received funding to study glutamate systems in individuals who co-use opioids and cocaine. Based on his research contributions, Dr. Stoops was named the 2013 Joseph Cochin Young Investigator by the College on Problems of Drug Dependence and the 2016 Psychologist of the Year from the Kentucky Psychological Association. He also received a Presidential Citation from the American Psychological Association in 2021. Dr. Stoops directs the Clinical Research Support Office at the University of Kentucky and is Associate Director for Clinical Research of the University of Kentucky Substance Use Priority Research Area. He is immediate past president of the College on Problems of Drug Dependence and is editor of Experimental and Clinical Psychopharmacology.


Ph.D.  Psychology, University of Kentucky
M.A. Psychology, University of Kentucky
A.B. Psychology, Davidson College




Current NIH funding as Principal Investigator/Multiple Principal Investigator:

Annual Meeting of the College on Problems of Drug Dependence (R13DA019790). National Institute on Drug Abuse.

Cardiovascular, Immune and Psychosocial Benefits of Reduced Cocaine Use (R01DA043938). National Institute on Drug Abuse.

Influence of Orexin Antagonism on Motivation for Cocaine (R01DA048617). National Institute on Drug Abuse.

Glutamatergic Mechanisms in Opioid and Cocaine Co-Use (R33DA049130). National Institute on Drug Abuse.

Influence of 5-HT1b Activation on the Abuse Related Effects of Cocaine (R01DA052203).

Selected Publications

Wheeler, P.B., Dogan, J.N., Stevens-Watkins, D. and Stoops W.W. (2021). Sleep Time Differs Among People who Co-Use Cocaine and Cannabis Compared to People who Only Use Cocaine. Pharmacology, Biochemistry and Behavior, 201, 173109.

Regnier, S.D., Lile, J.A., Rush, C.R. and Stoops, W.W. (2022). Clinical Neuropharmacology of Cocaine Reinforcement: A Narrative Review of Human Laboratory Self-Administration Studies. Journal of the Experimental Analysis of Behavior, 117, 420-441.

Stoops, W.W. (2022). A Brief Introduction to Human Behavioral Pharmacology: Methods, Design Considerations and Ethics, 45, 361-381.

Stoops, W.W., Strickland, J.C., Hatton, K.W., Hays, L.R., Rayapati, A.O., Lile, J.A. and Rush, C.R. (2022). Suvorexant Maintenance Enhances the Reinforcing but not Subjective and Physiological Effects of Intravenous Cocaine in Humans. Pharmacology, Biochemistry and Behavior, 220, 173466.

A full list of Dr. Stoops' publications can be found here:…