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Paula V. Monje, PhD

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pmonje@uky.edu
800 Rose Street, Whitney Hendrickson Building, Room 037

Positions

  • Associate Professor

College Unit(s)

Selected Publications

Monje P.V.*, Sant D, Wang G. (2018) Phenotypic and functional characteristics of human Schwann cells as revealed by cell-based assays and RNA-seq. Molecular Neurobiology 55 (8):6637-6660. PMID: 29327207

Monje P.V.* (2020) The properties of human Schwann cells: lessons from in vitro culture and transplantation studies. Glia 68 (4): 797-810. PMID: 32027424

Monje P.V.* (2020) Schwann cell cultures: biology, technology and therapeutics. Cells. 9, 1848 (1-24 p). Special Issue on ‘Schwann cells: from formation to clinical significance’. PMID: 32781699

Peng K., Sant D., Andersen N., Silvera S., Camarena V., Graham R., Khan A., Xu, X.M., Wang G., Monje P.V.* (2020) Magnetic separation of cultured peripheral nerve resident cells underscores key molecular features of human Schwann cells and fibroblasts: an immunochemical and transcriptomics approach. Scientific Reports 10(1):18433. PMID: 33116158

Monje P.V.*, Deng L, Xu, X.M. (2021) Human Schwann cell transplantation in spinal cord injury: prospects and challenges for translational medicine. Frontiers in Cellular Neuroscience https://doi.org/10.3389/fncel.2021.690894

Monje P.V.*, Bacallao K., Aparicio G., Lalwani A (2021) Heregulin activity assays for residual testing of cell therapy products. Biological Procedures Online 23, 22, https://doi.org/10.1186/s12575-021-00157-5

Chau M.J., Quintero J.E., Monje P.V., Voss R., Gerhardt G., van Horne C. (2022) Using an injury paradigm to enhance the regenerative mechanisms of an investigational human cell therapy. Cell Transplantation. doi:10.1177/09636897221123515. PMID: 36169034; PMCID: PMC9523845.

Aparicio G.I., Monje P.V.* (2023) Human Schwann Cells in vitro I. Nerve Tissue Processing, Pre-degeneration, Isolation and Culturing of Primary Cells. Bio-protocol 13(15): e4748. DOI: 10.21769/BioProtoc.4748.

Monje, P.V.* (2023) Human Schwann cells in vitro II. Passaging, purification, banking and labeling of established cultures. Bio-protocol 13(22): e4882. DOI: 10.21769/BioProtoc.4882.

Monje, P.V.* (2023). Human Schwann Cells in vitro III. Analytical Methods and a Practical Approach for Quality Control. Bio-protocol 13(19): e4840. DOI: 10.21769/BioProtoc.4840.

Aparicio GI, Quintero JE, Plum L, Deng L, Wanczyk K, Henry M, Lynch E, Murphy M, Gerhardt GA, van Horne CG, Monje P.V.*. Identification of cellular and noncellular components of mature intact human peripheral nerve. J Peripher Nerv Syst. 2024 Jul 7. doi: 10.1111/jns.12643. Epub ahead of print. PMID: 38973168.

Scholars@UK PubMed