Why did you choose the University of Kentucky?
My whole family is here, either works or study at UK. Also, I did an observership and research in the department of pathology at UK for several months which made me fall in love with this environment, with amazing and diverse faculty, residents and staff. The attendings here are all friendly, non-judgmental and very supportive, most importantly they value our individual professional growth mentally and physically. The PAs and other staff are highly skilled and very helpful, and the workloads and educational goals are well designed.
What are your hobbies?
Painting, gardening, swimming, binge watching TV shows.
Di J, Qasem SA. Primitive non-neural granular cell tumor: Literature review. Hum Pathol Rep. 2022 (submitted by invitation). Di J, Siddique I, Williams CK, et al. Exophers are components of mammalian cell neurobiology in health and disease. bioRxiv 2021.12.06.471479; doi: https://doi.org/10.1101/2021.12.06.471479. Status: Bio Archives Preprint available, and under review at CELL Press). Di J, Siddique I, Li Z, etc. The molecular tweezer CLR01 improves behavioral deficits and reduces tau pathology in P301S-tau transgenic mice. Alzheimer Res Ther. 2021, Jan; 13(6): 1-20. PMID: 33397489. (Impact Factor: 6.7) Di J, Li J, O’Hara B, etc. The role of GABAergic neural circuits in the pathogenesis of autism spectrum disorder. Int J Dev Neurosci. 2020, Feb; 80(2): 73-85. PMID: 31910289. (Impact Factor: 2.5) Shin W.S, Di J, Murray K.A, etc. Different amyloid-beta self-assemblies have distinct effects on intracellular tau aggregation. Front. Mol. Neurosci. 2019, Nov; 12(268): 268. PMID: 31787880. (Impact Factor: 5.6) Shin W.S, Di J, Cao Q, etc. Amyloid beta-protein oligomers promote the uptake of tau fibril seeds potentiating intracellular tau aggregation. Alzheimer Res Ther. 2019, Oct; 11(1): 86-99. PMID: 31627745. (Impact Factor: 6.7) Di J, Despres C, F.X, etc. Major differences between the self-assembly and seeding behavior of heparin-induced and in vitro phosphorylated tau and their modulation by potential inhibitors. ACS Chem. Biol. 2019, Jun; 14(6): 1363-1379. PMID: 31046227. (Impact Factor: 5.1) Bitan G, Despres C, Di J, etc. Major differences between the self-assembly, seeding behavior, and interaction with modulators of heparin-induced versus in-vitro phosphorylated tau. Alzheimers. Dement. 2019, Jul; 15(7S): 524-525. (Impact Factor: 6.7) Di J, Li Z, Siddique I, etc. The molecular tweezer CLR01 ameliorates pathology in the P301S-Tau mouse model. Alzheimers. Dement. 2019, Jul; 15(7S): 236-7. (Impact Factor: 6.7) Wen G, Di J, Li Q, etc. Efficient method for transfer of microinjected eggs to mouse ampulla for generation transgenic mice. SpringPlus. 2016, Dec; 5(1): 2076. PMID: 28018784. Di J, Cohen L.S, Corbo C.P, etc. Abnormal tau induces cognitive impairment through two different mechanisms: synaptic dysfunction and neuronal loss. Sci Rep. 2016, Feb; 6(0): 20833. PMID: 26888634. (Impact Factor: 5.7) Di J, Alonso A.C, Elidrissi A. Low level of nuclear phosphorylated tau is associated with cognitive impairment at early stage of the disease whereas an increase in the amount of this protein associates with neuronal death. Alzheimers. Dement. 2015, Nov; 11(7S): 355. (Impact Factor: 6.7) Wang H, Di J, Sun Y, etc. Biocompatible PEG-Chitosan @ carbon dots hybrid nanogels for two-photon fluorescence imaging, near-infrared light/pH dual-responsive drug carrier, and synergistic therapy. Adv. Funct. Mater. 2015, Jul; 25(34): 5537-5547. (Impact Factor: 18.8) Wang H, Sun Y, Yi J, Fu J, Di J, etc. Fluorescent porous carbon nanocapsules for two-photon imaging, NIR/pH dual-responsive drug carrier, and photothermal therapy. Biomaterials. 2015, Jun; 53(0): 117-126. PMID: 25890712. (Impact Factor: 12.5) Zhang L, Di J. The transcriptional activator Ino2p dissociates from the yeast INM1 promoter in induction. DNA Cell Biol. 2014, Dec; 33(12): 863-8. PMID: 25211324. (Impact Factor: 3.3) Butt I, Hong A, Di J, etc. The effects of serotonin1A receptor on female mice body weight and food intake are associated with the differential expression of hypothalamic neuropeptides and the GABAA receptor. Neuropeptides. 2014, Oct; 48(5): 313-8. PMID: 25130282. (Impact Factor: 3.2) Beharry C, Cohen L.S, Di J, etc. Tau-induced neurodegeneration: mechanisms and targets. Neurosci bull. 2014, Apr; 30(2): 346-58. PMID: 24733656. (Impact Factor: 5.2) Zhao H, Di J, Liu W, etc. Involvement of GSK3 and PP2A in ginsenoside Rb1's attenuation of aluminum-induced tau hyperphosphorylation. Behav brain res. 2013, Mar; 241(0): 228-34. PMID: 23219964. (Impact Factor: 3.3) Yang X, Di J, Zhang Y, etc. The Rho-kinase inhibitor inhibits proliferation and metastasis of small cell lung cancer. Biomed Pharmacother. 2011, Dec; 66(3): 221-7. PMID: 22425182. (Impact Factor: 6.5) Fan J, Li X, Zhong L, Tong H, Di J, etc. MCP-1, ICAM-1 and VCAM-1 are present in early aneurysmal dilatation in experimental rats. Folia Histochem Cytobiol. 2010, Sep; 48(3): 61-4. PMID: 1071353. Book chapter: R Malik, J Di, G Nair, etc. Using molecular tweezers to remodel abnormal protein self-assembly and inhibit the toxicity of amyloidogenic proteins (2018) 1777: 369-386. Methods Mol. Biol.