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Hong S. Lu, MD, PhD


741 South Limestone Street, Biomedical/Biological Sciences Research Building, Rm: B249


  • Associate Professor

College Unit(s)

Other Affiliation(s)
  • CVRC - Core Faculty
  • Nutritional Sciences Graduate Faculty

Biography and Education



MD, Zhejiang University College of Medicine, Hangzhou, China

PhD, Kanazawa University Graduate School of Medical Sciences, Kanazawa, Japan

Postdoctoral Fellow, University of Kentucky, Lexington, KY


Cardiovascular diseases are the leading cause of death in the nation and industrialized nations, accounting for nearly 50% of all deaths. My research focuses on atherosclerosis, aortic aneurysms and dissections, and renin-angiotensin regulations of cardiovascular functions. For both atherosclerosis and aortic aneurysms, my research aims to explore pharmacological inhibition of the renin angiotensin system and mechanisms related to the renin-angiotensin system (Collaboration with Dr. Alan Daugherty at the University of Kentucky). For atherosclerosis, I also study mechanisms and potential therapies related to cGAS-STING-mediated dyslipidemia and inflammation (Collaboration with Dr. Ying Shen at Baylor College of Medicine). At the same time, I study the vascular biology of LRP1 (LDL receptor-related protein 1; Collaboration with Dr. Dudley Strickland at the University of Maryland) and PAI-1 (plasminogen activator inhibitor 1; Collaboration with Dr. Daniel Lawrence at the University of Michigan), and the renin-angiotensin regulation in kidney by megalin (LRP2: LDL receptor-related protein 2).

Selected Publications

Google Scholar Research Gate Pubmed Publications