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LEXINGTON, Ky. (July 2, 2021) — A new University of Kentucky College of Medicine study suggests that time-restricted eating may be able to help people with Type 2 diabetes reduce nocturnal hypertension, which is characterized by elevated blood pressure at night.

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In his 40 years at the University of Kentucky College of Medicine, Michael T. Piascik, PhD, has mentored hundreds of medical students and graduate students while bringing key funding to the college as a researcher to help produce groundbreaking discoveries in pharmacology.

After a long and distinguished career, Dr. Piascik has announced he will retire, effective July 1.

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LEXINGTON, Ky. (April 27, 2021) — Annually, Best of Cell Press celebrates the highest-impact research published in their journals during the previous year. A paper by Barbara Nikolajczyk, Ph.D., professor of Pharmacology and Nutritional Sciences and associate director for Translational Research in Diabetes at the University of Kentucky, has been included in “Best of Cell Metabolism 2020.” The paper focuses on age-associated inflammation.

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PILOT PROJECT FUNDING OPPORTUNITY
THE CENTER FOR BIOMEDICAL RESEARCH EXCELLENCE ON OBESITY AND CARDIOVASCULAR DISEASES (COCVD)

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The University of Kentucky College of Medicine would like to recognize and congratulate its departments that made it in the Blue Ridge Institute for Medical Research (BRIMR) 2020 rankings.

BRIMR rankings, released each year, are reflective of top National Institutes of Health (NIH) funding to U.S. medical schools and rank institutions based on specialty. Rankings are derived from data compiled and released by the NIH shortly after the federal fiscal year closes.

Highlights of the rankings:

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The seventh annual Healthy Hearts for Women virtual symposium will take place Friday, Feb. 5, 2021. A virtual round table hosted by Women in Medicine and Science (WIMS) will follow the symposium.

8:30 a.m.-Noon
Healthy Hearts for Women Symposium

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LEXINGTON, Ky. (Jan. 20, 2021) — More than 5.7 million Americans live with Alzheimer’s disease and that number is projected to triple by 2050. Despite that growing number, there is not yet a cure.

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As part of its commitment toward creating a more inclusive work and learning environment, the University of Kentucky College of Medicine has established additional leadership roles in the Office of Diversity, Equity, and Inclusion. The college is pleased to announce the appointment of Kevin Pearson, PhD, to oversee progress in research as the inaugural director of inclusive research initiatives.  

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Special Seminar followed by Diversity Roundtable

Location: https://uky.zoom.us/j/81146001530
Friday, December 4, 2020

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LEXINGTON, KY. (Oct. 27, 2020) — A $2.9 million grant from the National Institutes of Health (NIH) is supporting a multidisciplinary team of University of Kentucky researchers in continuing their work to find therapeutic strategies to resolve neurovascular inflammation and repair blood-brain barrier dysfunction in epilepsy.

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A new study led by researchers at the University of Kentucky Markey Cancer Center and UK Department of Pharmacology and Nutritional Sciences demonstrates the potential benefit of using an anti-leukemic drug nilotinib – most commonly used to treat chronic myelogenous leukemia – to overcome therapy resistance in metastatic melanoma.

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LEXINGTON, Ky. (Sept. 2, 2020) — A new University of Kentucky College of Medicine study provides insight into how a protein called angiotensinogen (AGT) contributes to blood pressure regulation and atherosclerosis.

AGT is a member of the renin-angiotensin system, a hormone system in the human body that regulates blood pressure and fluid balance. AGT produces angiotensin II, which regulates blood pressure and contributes to atherosclerosis, or the buildup of plaque in the arteries.

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The COVID-19 pandemic has created an ever-changing environment requiring quick adjustment, especially in the field of research. In response to the pandemic, scientists at UK ceased non-essential research activity in the spring, and education was moved to online platforms. While these measures were necessary to ensure safety for faculty and learners, graduate students in the University of Kentucky College of Medicine Integrated Biomedical Sciences (IBS) PhD program saw their progress interrupted.
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Nika Larian, a postdoctoral researcher in the University of Kentucky College of Medicine’s Department of Pharmacology and Nutritional Sciences, has been awarded a Science & Technology Policy Fellowship with the American Association for the Advancement of Science (AAAS). The AAAS Science & Technology Policy Fellowships (STPF) aim to support evidence-based policymaking by leveraging the knowledge and analytical mindset of science and engineering experts, and foster leaders for a strong U.S. science and technology enterprise.
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LEXINGTON, Ky. (July 14, 2020) — A new study by researchers at the University of Kentucky identifies a novel function of the enzyme spermine synthase (SMS) to facilitate colorectal cancer growth.

SMS is an enzyme that produces spermine from spermidine, which has been shown to be important for cell growth. However, excessive accumulation of spermidine can have harmful effects on cell viability. How cancer cells maintain a relatively high level of spermidine but below the toxic threshold to facilitate tumor growth is not well understood.

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The NIH Center of Biomedical Research Excellence (COBRE) on Obesity and Cardiovascular Diseases, in collaboration with the Center for Clinical and Translational Sciences (CCTS) announce the availability of limited funds to support pilot projects focused on research examining obesity-associated diseases.

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The first NIH-wide strategic plan for nutrition research emphasizes cross-cutting, innovative opportunities to advance nutrition research across a wide range of areas, from basic science to experimental design to research training. These opportunities complement and enhance ongoing research efforts across NIH to improve health and to prevent or combat diseases and conditions affected by nutrition.

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Hollie Swanson, a professor and researcher in the Department of Pharmacology and Nutritional Sciences in the College of Medicine, has been elected to serve as a faculty trustee on the University of Kentucky Board of Trustees. Under University Senate rules, Swanson was the top vote getter among three candidates in the election completed last week. "It is an honor and a privilege to be able to represent the UK faculty as their representative on the Board of Trustees,” Swanson said.
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It’s widely known that when it comes to diet, fast food isn’t the healthiest choice. Expanding on this knowledge, a recent study by a researcher at the University of Kentucky College of Medicine found that the inclusion of fructose-sweetened drinks with high-fat foods might add to the negative effects on one’s body.