The Protein Production Facility promotes recombinant protein production and characterization of macromolecules, making available well-maintained equipment and instrumentation not normally found within individual laboratories. In addition, this facility provides a single chain antibody (nanobody) production service. The mission of the Protein Production Facility is to provide training and access to its facilities for members of the Center as well as the research community in general. Projects are undertaken on a service basis. A full time staff member maintains the equipment, provides training to new users, works with researchers to make the best use of the instrumentation, and oversees scheduling.

The facility has the capabilities to assist researchers in moving their project from protein expression to biophysical characterization to protein crystallization. We also assist in cell culture, protein production and purification, and macromolecular characterization through a number of techniques. Nanobodies are produced in alpacas through the facility. Researchers can make use of instrumentation on a regular basis unassisted by personnel after initial training. Protein Production Facility personnel offer training on all instruments and equipment, as well as a higher-level of assistance when projects warrant. Additionally, service projects are undertaken, including protein production, using heterologous expression in bacteria, insect, or mammalian cells, and protein purification.

Current charges for the services provided by the facility are listed below. 

To apply to use the Protein Production Facility, or for further information, click here: