Center for Molecular Medicine Program Initiative The thematic focus of the Center for Molecular Medicine, a National Institute of General Medical Sciences (NIGMS) funded Center of Biomedical Research Excellence (COBRE), is to understand the molecular basis of human disease. Through an NIH/NIGMS P30 grant, the center established four cores. The long-term goals of the center include enhancing multidisciplinary research on the study of human disease, and enhancing research competitiveness, and building, strengthening and creating new core facilities to enhance the capabilities of researchers across the University of Kentucky and elsewhere. Image Genetic Technologies Services previously provided by the Genetic Technologies Core will now be offered through the Protein Core. Image Organic Synthesis The Organic Synthesis core focuses on providing investigators with small, organic molecules that cannot be obtained commercially for their research. Image Protein The Protein Core provides services that include: protein production in bacteria, yeast or insect cells, protein purification, and biophysical characterization of proteins. Image Nanobody Production Through resources provided by the NIGMS, the University of Kentucky’s COBRE Protein Core is now producing single domain antibodies in alpacas for investigators. More UK Cores Division of Laboratory Animal Resources (DLAR) DLAR supports the biomedical research community at the University of Kentucky by providing the highest quality veterinary services and humane care and treatment to the animals in our care. Magnetic Resonance Imaging and Spectroscopy Center (MRISC) The Magnetic Resonance Imaging and Spectroscopy Center (MRISC) is a service and consultation center supporting basic and clinical research at the University of Kentucky. Light Microscopy Core The facility provides access to and expertise in a wide range of advanced imaging instrumentation that includes confocal, multiphoton, and super-resolution microscopes. Proteomics Core Facility The Proteomics Core Facility offers proteomic analysis services to the scientific community on a fee-for-service basis. Our focus is the identification of proteins and peptides and characterization of protein modifications. Rodent Behavior Core (RBC) Our goals are to conduct reliable and validated mouse behavior tests for investigators at the University of Kentucky, ensure that qualified and trained investigators have access to state-of-the-art instrumentation and expertise necessary to perform behavior tests and to provide assistance in the design, implementation, and analysis of behavioral experiments in mice.
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